EPH Receptor B4 antibody (Extracellular)

Catalog No. ABIN966076

Product Details anti-EPH Receptor B4 Antibody

Target: EPH Receptor B4 (EPHB4)

Binding Specificity: Extracellular

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EPH Receptor B4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Ascitic fluid

Immunogen: Purified recombinant extracellular fragment of human EPHB4 fused with hIgGFc tag expressed in HEK293 cell line.

Clone: 5B5

Isotype: IgG1

Application Details

Application Notes: Western Bloting: 1/500 - 1/2000.
Immunofluorescence: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Handling

Format: Liquid

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

References for anti-EPH Receptor B4 antibody (ABIN966076)

Kubota: "[What is drug-epidemiology?]." in: Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, Vol. 96, Issue 6, pp. 1083-90, (2007) (PubMed).

Tachibana, Tonomoto, Hyakudomi, Hyakudomi, Hattori, Ueda, Kinugasa, Yoshimura: "Expression and prognostic significance of EFNB2 and EphB4 genes in patients with oesophageal squamous cell carcinoma." in: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, Vol. 39, Issue 8, pp. 725-32, (2007) (PubMed).

Target Details for EPH Receptor B4

Target: EPH Receptor B4 (EPHB4)

Alternative Name: EPHB4 (EPHB4 Products)

Synonyms: HTK antibody, MYK1 antibody, TYRO11 antibody, htk antibody, myk1 antibody, ephB4a antibody, tyro11 antibody, ephb4b antibody, MGC130997 antibody, AI042935 antibody, Htk antibody, MDK2 antibody, Myk1 antibody, Tyro11 antibody, cb646 antibody, ephB4 antibody, rtk5 antibody, EphB-rtk8 antibody, cb417 antibody, rtk8 antibody, EPH receptor B4 antibody, EPH receptor B4 L homeolog antibody, EPH receptor B4 S homeolog antibody, Eph receptor B4 antibody, eph receptor B4a antibody, eph receptor B4b antibody, EPHB4 antibody, ephb4.L antibody, ephb4.S antibody, ephb4 antibody, Ephb4 antibody, ephb4a antibody, ephb4b antibody

Background: EphB4: EPH receptor B4, also known as Htk, Myk1, Tyro11. Entrez Protein: NP_004435. It is a member of the Eph receptor family, which bind the ephrin ligand family. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The EphB4 protein binds to ephrin-B2 and plays an essential role in vascular development.
Synonyms: HTK, MYK1, TYRO11

Molecular Weight: 108kDa

Gene ID: 2050

Pathways: RTK Signaling