ULBP1 antibody

Catalog No. ABIN966609

Product Details anti-ULBP1 Antibody

Target: ULBP1 (UL16 Binding Protein 1 (ULBP1))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ULBP1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Immunogen: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to middle amino acid residues of mouse MULT1 (UL16-binding protein-like transcript 1)

Application Details

Restrictions: For Research Use only

Handling

Storage: 4 °C

References for anti-ULBP1 antibody (ABIN966609)

Smalley, Natarajan, Mondal, Best, Goldman, Shanthappa, Pellowe, Dash, Saha, Khiste, Ramadurai, Eton, Smalley, Brown, Thayakumar, Rahman, Arai, Kohandel, Sengupta, Goldman: "Nanoengineered Disruption of Heat Shock Protein 90 Targets Drug-Induced Resistance and Relieves Natural Killer Cell Suppression in Breast Cancer." in: Cancer research, Vol. 80, Issue 23, pp. 5355-5366, (2021) (PubMed).

Spielmann, Mattheis, Jung, Rauße, Glaß, Bähr, Quandt, Oswald, Kielstein: "Effects of obesity on NK cells in a mouse model of postmenopausal breast cancer." in: Scientific reports, Vol. 10, Issue 1, pp. 20606, (2020) (PubMed).

Lenac, Budt, Arapovic, Hasan, Zimmermann, Simic, Krmpotic, Messerle, Ruzsics, Koszinowski, Hengel, Jonjic: "The herpesviral Fc receptor fcr-1 down-regulates the NKG2D ligands MULT-1 and H60." in: The Journal of experimental medicine, Vol. 203, Issue 8, pp. 1843-50, (2006) (PubMed).

Diefenbach, Hsia, Hsiung, Raulet: "A novel ligand for the NKG2D receptor activates NK cells and macrophages and induces tumor immunity." in: European journal of immunology, Vol. 33, Issue 2, pp. 381-91, (2003) (PubMed).

Carayannopoulos, Naidenko, Fremont, Yokoyama: "Cutting edge: murine UL16-binding protein-like transcript 1: a newly described transcript encoding a high-affinity ligand for murine NKG2D." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 169, Issue 8, pp. 4079-83, (2002) (PubMed).

Target Details for ULBP1

Target: ULBP1 (UL16 Binding Protein 1 (ULBP1))

Alternative Name: MULT1 (ULBP1 Products)

Synonyms: RAET1I antibody, A430108B07Rik antibody, MULT1 antibody, ULBP1 antibody, UL16 binding protein 1 antibody, UL16 binding protein 21 antibody, NKG2D ligand 1 antibody, ULBP1 antibody, ULBP21 antibody, Ulbp1 antibody, LOC100683099 antibody

Background: MULT1 (UL16-binding protein-like transcript 1) is expressed in adult parenchyma, possesses MHC class I-like alpha 1 and alpha 2 domains and a large cytoplasmic domain, and binds NKG2D with high affinity. Mouse cytomegalovirus (MCMV) molecule fcr-1 promotes a rapid downregulation of NKG2D ligands murine UL16-binding protein like transcript (MULT)-1 and H60 from the cell surface.
Synonyms: Ulbp1(UL16 binding protein 1)

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process