APH1C Protein (AA 1-258) (His tag)
custom-made
APH1C
Origin: Mouse
Host: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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- Target
- APH1C (Anterior Pharynx Defective 1c Homolog (APH1C))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-258
- Origin
- Mouse
- Source
- HEK-293 Cells
- Purification tag / Conjugate
- This APH1C protein is labelled with His tag.
- Purpose
- Predefined custom protein recombinant Aph1c Protein expressed in mammalian cells.
- Sequence
- MTLPVFFGCA FIAFGPAFAL YLFTIATDPL RVIFLIAGAF FWLVSLLLSS MFWFLVRVIT NNRDESVQNY LLIFGALLSV CIQELFRLAY YKLLKKASEG LKSINPEEDI APSMRLLAYV SGLGFGIMSG VFSFVNTLSN SLGPGTVGIH GDSPQFFLNS AFMTLVVIML HVFWGVVFFD GCEKNKWYTL LTVLLTHLVV STQTFLSPYY EVNLVTAYII MVLMGIWAFY VAGGSCRSLK FCLLCQDKDF LLYNQRSR Sequence without tag. The proposed Strep-Tag is based on experience with the expression system. Our team may suggest an additional tag depending on the complexity of the protein. If you have a special request, please contact us.
- Specificity
- If you are looking for a specific domain and are interested in a partial protein or a different isoform, please contact us regarding an individual offer.
- Characteristics
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Key Benefits:
- Predefined custom protein - from design to production - by highly experienced protein experts.
- Protein expressed in mammalian cells and purified in one-step affinity chromatography
- The optimized expression system ensures reliability for intracellular, secreted and transmembrane proteins.
- State-of-the-art algorithm used for plasmid design (Gene synthesis).
If you are not interested in a full length protein, please contact us for individual protein fragments.
The big advantage of ordering our predefined custom proteins in comparison to ordering custom-made proteins from other companies is that there is no financial obligation in case the protein cannot be expressed or purified. - Purity
- > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
- Grade
- custom-made
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- Application Notes
- We expect the protein to work for functional studies. As the protein has not been tested for functional studies yet we cannot offer a guarantee though.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- The buffer composition is at the discretion of the manufacturer.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C.
- Expiry Date
- 12 months
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- Target
- APH1C (Anterior Pharynx Defective 1c Homolog (APH1C))
- Alternative Name
- Aph1c
- Background
- Putative gamma-secretase subunit APH-1C,FUNCTION: Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (amyloid-beta precursor protein). {ECO:0000250}.
- Molecular Weight
- 29.0 kDa
- UniProt
- Q9DCZ9
- AlphaFold
- Q9DCZ9
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