We are preparing the requested document. Please wait, this may take a while...!
|Antigen||Lamin B1 (LMNB1) Antibodies|
|Epitope||C-Term, AA 466-496 Alternatives|
|Conjugate||This Lamin B1 antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Western Blotting (WB)
|2 references available|
|Supplier||Log in to see|
Product Details anti-Lamin B1 AntibodyTarget Details Lamin B1 Application Details Handling References for anti-Lamin B1 antibody (ABIN497968) Images
|Specificity||Recognizes Lamin B1 (C-term).|
|Cross-Reactivity (Details)||Species reactivity (tested):Human.|
|Purification||Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Immunogen||This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 466-496 amino acids from the C-terminal region of Human Lamin B1. Genename: LMNB1|
Target Details Lamin B1Product Details anti-Lamin B1 Antibody Application Details Handling References for anti-Lamin B1 antibody (ABIN497968) Images back to top
|Alternative Name||Lamin-B1 (LMNB1) (LMNB1 Antibody Abstract)|
|Background||The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Lamin B1 is one of the two B type proteins, B1.Synonyms: LMN2, LMNB, LMNB-1, LMNB1, Lamin-B1, Nuclear Envelope Marker|
|Pathways||Apoptosis, Caspase Cascade in Apoptosis|
Application DetailsProduct Details anti-Lamin B1 Antibody Target Details Lamin B1 Handling References for anti-Lamin B1 antibody (ABIN497968) Images back to top
ELISA: 1/1,000Western blotting: 1/50approx. 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-Lamin B1 Antibody Target Details Lamin B1 Application Details References for anti-Lamin B1 antibody (ABIN497968) Images back to top
|Buffer||PBS with 0.09 % (W/V) Sodium Azide as preservative.|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.|
References for anti-Lamin B1 antibody (ABIN497968)Product Details anti-Lamin B1 Antibody Target Details Lamin B1 Application Details Handling Images back to top
Brussino, Vaula, Cagnoli, Mauro, Pradotto, Daniele, Di Gregorio, Barberis, Arduino, Squadrone, Abete, Migone, Calabrese, Brusco: "A novel family with Lamin B1 duplication associated with adult-onset leucoencephalopathy." in: Journal of neurology, neurosurgery, and psychiatry, Vol. 80, Issue 2, pp. 237-40, 2009
Nicholls: "The effects of starvation and light on intra-mitochondrial granules in Physarum polycephalum." in: Journal of cell science, Vol. 10, Issue 1, pp. 1-14, 1972
ImagesProduct Details anti-Lamin B1 Antibody Target Details Lamin B1 Application Details Handling References for anti-Lamin B1 antibody (ABIN497968) back to top