anti-Rat (Rattus) Lamin B1 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended Lamin B1 Antibody (supplied by: Log in to see )

Antigen
Lamin B1 (LMNB1) Antibodies
  • MGC52550
  • Lamin-L(I)
  • lamin-b
  • lmn
  • lmn2
  • lmnb
  • LMNB1
  • ADLD
  • LMN
  • LMN2
  • LMNB
  • fc06g01
  • wu:fc06g01
  • lamin B1 L homeolog
  • lamin B1
  • lmnb1.L
  • lmnb1
  • LMNB1
  • Lmnb1
Epitope
AA 266-583
17
11
10
8
6
4
4
4
4
4
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
169
80
67
13
11
11
6
5
4
4
3
3
2
2
2
1
1
Host
Rabbit
100
46
31
Clonality
Polyclonal
Conjugate
This Lamin B1 antibody is un-conjugated
3
3
3
2
2
2
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
168
79
61
34
33
27
17
14
11
7
5
2
1
1
1
Options
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Catalog No. ABIN3042505
$ 280.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
31.25679 ABIN3187719 ELISA IHC (p) WB Rabbit IgG Internal Region Log in to see Polyclonal 0
26.5 ABIN3043687 ICC IHC (fro) IHC (p) WB Rabbit IgG AA 570-586, C-Term Log in to see Polyclonal 18
11.497463 ABIN1108013 IHC (fro) IF IHC (p) IP WB Rabbit IgG C-Term Log in to see Polyclonal 0
11.497463 ABIN498558 IHC (p) WB Rabbit Log in to see Polyclonal 0
11.472993 ABIN5946846 ICC IF IHC IHC (p) IP WB Rabbit IgG C-Term Log in to see SI17-06 0
10 ABIN3031586 ICC IHC (fro) IHC (p) WB Rabbit IgG AA 570-586 Log in to see Polyclonal 0
7 ABIN735203 IF (p) IHC (p) WB Rabbit IgG AA 382-431 Log in to see Polyclonal 0
4 ABIN5957131 IF IHC (p) IP WB Mouse IgG Log in to see 4K2 0
4 ABIN5957132 ELISA IF IHC (p) WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2892926 IHC IHC (p) WB Rabbit Leu75 Log in to see Polyclonal 0
1 ABIN2613096 IHC IHC (p) WB Rabbit N-Term Log in to see Polyclonal 0
1 ABIN5957134 ELISA IHC (p) WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN4951627 ICC IHC (fro) IHC (p) WB Rabbit IgG AA 266-583 Log in to see Polyclonal 0

General

Antigen Lamin B1 (LMNB1) Antibodies
Epitope AA 266-583
(17), (11), (10), (8), (6), (4), (4), (4), (4), (4), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(169), (80), (67), (13), (11), (11), (6), (5), (4), (4), (3), (3), (2), (2), (2), (1), (1)
Host Rabbit
(100), (46), (31)
Clonality
Polyclonal
Conjugate This Lamin B1 antibody is un-conjugated
(3), (3), (3), (2), (2), (2)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(168), (79), (61), (34), (33), (27), (17), (14), (11), (7), (5), (2), (1), (1), (1)
Pubmed 15 references available
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Product Details anti-Lamin B1 Antibody

Target Details Lamin B1 Application Details Handling References for anti-Lamin B1 antibody (ABIN3042505) Images
Purpose Rabbit IgG polyclonal antibody for Lamin-B1(LMNB1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Cross-Reactivity (Details) No cross reactivity with other proteins.
Characteristics Rabbit IgG polyclonal antibody for Lamin-B1(LMNB1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: lamin B1
Protein Name: Lamin-B1
Purification Immunogen affinity purified.
Immunogen E.coli-derived human Lamin B1 recombinant protein (Position: Q266-C583). Human Lamin B1 shares 95.9% and 95% amino acid (aa) sequence identity with mouse and rat Lamin B1, respectively.
Isotype IgG
Plasmids, Primers & others

Target Details Lamin B1

Product Details anti-Lamin B1 Antibody Application Details Handling References for anti-Lamin B1 antibody (ABIN3042505) Images back to top
Antigen
Alternative Name LMNB1 (LMNB1 Antibody Abstract)
Background Lamin-B1 is a protein that in humans is encoded by the LMNB1 gene. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1.

Synonyms: ADLD antibody|lamin B1 antibody|Lamin-B1 antibody|LMN antibody|LMN2 antibody|LMNB antibody| Lmnb1 antibody|LMNB1_HUMAN antibody| MGC111419 antibody|OTTHUMP00000159218 antibody
Gene ID 4001
UniProt P20700
Pathways Apoptosis, Caspase Cascade in Apoptosis

Application Details

Product Details anti-Lamin B1 Antibody Target Details Lamin B1 Handling References for anti-Lamin B1 antibody (ABIN3042505) Images back to top
Application Notes WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
Comment

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions For Research Use only

Handling

Product Details anti-Lamin B1 Antibody Target Details Lamin B1 Application Details References for anti-Lamin B1 antibody (ABIN3042505) Images back to top
Format Lyophilized
Reconstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Concentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

References for anti-Lamin B1 antibody (ABIN3042505)

Product Details anti-Lamin B1 Antibody Target Details Lamin B1 Application Details Handling Images back to top
Product cited in:

Chen, Luo, Lin, Kuang, Song: "Simulated microgravity inhibits osteogenic differentiation of mesenchymal stem cells via depolymerizing F-actin to impede TAZ nuclear translocation." in: Scientific reports, Vol. 6, pp. 30322, 2018

Timoshevskiy, Herdy, Keinath, Smith: "Cellular and Molecular Features of Developmentally Programmed Genome Rearrangement in a Vertebrate (Sea Lamprey: Petromyzon marinus)." in: PLoS genetics, Vol. 12, Issue 6, pp. e1006103, 2017

Shen, Sun, Xia, Meng, Lei, Zhao, Tang, Xue, Chen: "Overexpression of DJ-1 reduces oxidative stress and attenuates hypoxia/reoxygenation injury in NRK-52E cells exposed to high glucose." in: International journal of molecular medicine, Vol. 38, Issue 3, pp. 729-36, 2017

Chen, Jiang, Gu, Lai, Liu, Zhang: "Protection of Nrf2 against arsenite-induced oxidative damage is regulated by the cyclic guanosine monophosphate-protein kinase G signaling pathway." in: Environmental toxicology, Vol. 32, Issue 8, pp. 2004-2020, 2017

Zhang, Zhang, Zhang, Jiao, Zhang, Wang, Gong: "Glutamine ameliorates lipopolysaccharide-induced cardiac dysfunction by regulating the toll-like receptor 4/mitogen-activated protein kinase/nuclear factor-kB signaling pathway." in: Experimental and therapeutic medicine, Vol. 14, Issue 6, pp. 5825-5832, 2017

Tang, Wang, Chen, Xu, Ye: "Clinicopathologic and prognostic significance of p21 (Cip1/Waf1) expression in bladder cancer." in: International journal of clinical and experimental pathology, Vol. 8, Issue 5, pp. 4999-5007, 2016

Chen, Lai, Yang, Ruan, Chaugai, Ning, Chen, Wang: "Trimetazidine prevents macrophage-mediated septic myocardial dysfunction via activation of the histone deacetylase sirtuin 1." in: British journal of pharmacology, Vol. 173, Issue 3, pp. 545-61, 2016

Bai, Zhang, Shen, Sun, Xia, Zhang, Liu, Wang, Yuan: "Hyperglycemia and hyperlipidemia blunts the Insulin-Inpp5f negative feedback loop in the diabetic heart." in: Scientific reports, Vol. 6, pp. 22068, 2016

Wu, Liu, Duan, Gao, Li, Wang, Song, Shao, Yang, Yang: "The Involvement of Protease Nexin-1 (PN1) in the Pathogenesis of Intervertebral Disc (IVD) Degeneration." in: Scientific reports, Vol. 6, pp. 30563, 2016

Shen, Wang, Wang, Wang, Yang, Shen, Wang, Guo, Liu, Xia, Jia, Wang: "Activation of volume-sensitive outwardly rectifying chloride channel by ROS contributes to ER stress and cardiac contractile dysfunction: involvement of CHOP through Wnt." in: Cell death & disease, Vol. 5, pp. e1528, 2015

Zhu, Liu, Li, Liu, Wang, Sun, Xiong, Jiang, Zheng, Hu: "Protein tyrosine phosphatase receptor U (PTPRU) is required for glioma growth and motility." in: Carcinogenesis, Vol. 35, Issue 8, pp. 1901-10, 2014

Liu, Ma, Wu, Li, Zhang, Han, Wang, Reindl, Wu, Ma: "Arginine deiminase augments the chemosensitivity of argininosuccinate synthetase-deficient pancreatic cancer cells to gemcitabine via inhibition of NF-?B signaling." in: BMC cancer, Vol. 14, pp. 686, 2014

Gao, Wu, Liu, Li, Song, Teng, Sheng, Liu, Yao, Chen, Jiang, Chen, Huang: "Interaction of NS2 with AIMP2 facilitates the switch from ubiquitination to SUMOylation of M1 in influenza A virus-infected cells." in: Journal of virology, Vol. 89, Issue 1, pp. 300-11, 2014

Yu, Chen, Wang, Kuang, Liu, Zhang, Du: "Neuroprotective effect of kaempferol glycosides against brain injury and neuroinflammation by inhibiting the activation of NF-?B and STAT3 in transient focal stroke." in: PLoS ONE, Vol. 8, Issue 2, pp. e55839, 2013

Zhang, Zhou, Wu, Zhang, Chen, Zha, Niu, Lu, Hao, Sun, Sun, Peng, Wang: "Cellular pharmacokinetic mechanisms of adriamycin resistance and its modulation by 20(S)-ginsenoside Rh2 in MCF-7/Adr cells." in: British journal of pharmacology, Vol. 165, Issue 1, pp. 120-34, 2012

Images

Product Details anti-Lamin B1 Antibody Target Details Lamin B1 Application Details Handling References for anti-Lamin B1 antibody (ABIN3042505) back to top
Supplier Images
Western Blotting (WB) image for anti-Lamin B1 (LMNB1) (AA 266-583) antibody (ABIN3042505) anti-Lamin B1 (LMNB1) (AA 266-583) antibody
Immunohistochemistry (IHC) image for anti-Lamin B1 (LMNB1) (AA 266-583) antibody (ABIN3042505) Anti- Lamin B1 Picoband antibody, IHC(P) IHC(P): Rat Intestine Tissue
Immunohistochemistry (IHC) image for anti-Lamin B1 (LMNB1) (AA 266-583) antibody (ABIN3042505) Anti- Lamin B1 Picoband antibody, IHC(P) IHC(P): Mouse Intestine Tissue
Immunohistochemistry (IHC) image for anti-Lamin B1 (LMNB1) (AA 266-583) antibody (ABIN3042505) Anti- Lamin B1 Picoband antibody, IHC(P) IHC(P): Human Mammary Cancer Tissue
Immunohistochemistry (IHC) image for anti-Lamin B1 (LMNB1) (AA 266-583) antibody (ABIN3042505) IHC analysis of Lamin B1 using anti-Lamin B1 antibody . Lamin B1 was detected in imm...
Immunohistochemistry (IHC) image for anti-Lamin B1 (LMNB1) (AA 266-583) antibody (ABIN3042505) IHC analysis of Lamin B1 using anti-Lamin B1 antibody . Lamin B1 was detected in imm...
Immunohistochemistry (IHC) image for anti-Lamin B1 (LMNB1) (AA 266-583) antibody (ABIN3042505) IHC analysis of Lamin B1 using anti-Lamin B1 antibody . Lamin B1 was detected in imm...
Immunohistochemistry (IHC) image for anti-Lamin B1 (LMNB1) (AA 266-583) antibody (ABIN3042505) IHC analysis of Lamin B1 using anti-Lamin B1 antibody . Lamin B1 was detected in fro...
Immunohistochemistry (IHC) image for anti-Lamin B1 (LMNB1) (AA 266-583) antibody (ABIN3042505) IHC analysis of Lamin B1 using anti-Lamin B1 antibody . Lamin B1 was detected in imm...
Immunohistochemistry (IHC) image for anti-Lamin B1 (LMNB1) (AA 266-583) antibody (ABIN3042505) IHC analysis of Lamin B1 using anti-Lamin B1 antibody . Lamin B1 was detected in fro...
Immunohistochemistry (IHC) image for anti-Lamin B1 (LMNB1) (AA 266-583) antibody (ABIN3042505) IHC analysis of Lamin B1 using anti-Lamin B1 antibody . Lamin B1 was detected in fro...