anti-Mouse (Murine) XIAP antibody for ELISA

Recommended XIAP Antibody (supplied by: Log in to see )

Antigen
X-Linked Inhibitor of Apoptosis (XIAP) Antibodies
  • API3
  • BIRC4
  • IAP-3
  • ILP1
  • MIHA
  • XLP2
  • hIAP-3
  • hIAP3
  • api3
  • birc4
  • ilp1
  • miha
  • xlp2
  • xxiap
  • 1110015C02Rik
  • Aipa
  • Api3
  • Birc4
  • IAP3
  • ILP-1
  • mXIAP
  • riap3
  • fb73d01
  • wu:fb73d01
  • zgc:91873
  • BIRC8
  • X-linked inhibitor of apoptosis
  • X-linked inhibitor of apoptosis L homeolog
  • XIAP
  • xiap
  • xiap.L
  • Xiap
Epitope
C-Term
21
17
15
9
9
8
8
6
5
5
5
4
4
4
3
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
184
93
62
7
5
5
2
Host
Rabbit
158
26
1
Clonality
Polyclonal
Conjugate
This XIAP antibody is un-conjugated
6
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
163
72
53
46
28
23
13
13
9
9
3
3
2
1
1
Supplier
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Catalog No. ABIN1003492
$ 511.06
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2888718 IHC (p) ELISA WB Rabbit IgG AA 53-102 Log in to see Polyclonal 0
1 ABIN3187502 ELISA IHC WB Rabbit IgG Ser144 Log in to see Polyclonal 0
1 ABIN3182566 ELISA IHC WB Rabbit IgG pSer87 Log in to see Polyclonal 0
1 ABIN1585518 ELISA IHC WB Rabbit C-Term Log in to see Polyclonal 0
1 ABIN1030806 IHC ELISA WB Rabbit C-Term Log in to see Polyclonal 0
1 ABIN1948934 IHC ELISA WB Alkaline Phosphatase (AP) Rabbit IgG N-Term Log in to see Polyclonal 0
1 ABIN1948936 IHC ELISA WB FITC Rabbit IgG N-Term Log in to see Polyclonal 0
1 ABIN1948938 IHC ELISA WB PE Rabbit IgG N-Term Log in to see Polyclonal 0
1 ABIN1948935 IHC ELISA WB APC Rabbit IgG N-Term Log in to see Polyclonal 0
1 ABIN1948937 IHC ELISA WB Biotin Rabbit IgG N-Term Log in to see Polyclonal 0
1 ABIN2568909 ELISA IHC WB Rabbit IgG N-Term Log in to see Polyclonal 0
1 ABIN1948933 IHC ELISA WB HRP Rabbit IgG N-Term Log in to see Polyclonal 0
1 ABIN3029644 IHC ELISA WB Rabbit Ig Fraction AA 1-30 Log in to see Polyclonal 0
1 ABIN1094743 IF IHC ELISA WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN1094742 IF IHC ELISA WB Rabbit IgG Log in to see Polyclonal 0
1 ABIN2960000 IF IHC ELISA WB Rabbit IgG C-Term Log in to see Polyclonal 0
1 ABIN4955797 ELISA IHC WB Rabbit Ig Fraction AA 1-30 Log in to see Polyclonal 0
1 ABIN1887439 IHC ELISA WB Rabbit C-Term Log in to see Polyclonal 0
1 ABIN865848 ELISA WB Mouse IgG2b Log in to see 0
1 ABIN865847 ELISA WB Mouse IgG1 Log in to see 0

General

Antigen X-Linked Inhibitor of Apoptosis (XIAP) Antibodies
Epitope C-Term
(21), (17), (15), (9), (9), (8), (8), (6), (5), (5), (5), (4), (4), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(184), (93), (62), (7), (5), (5), (2)
Host Rabbit
(158), (26), (1)
Clonality
Polyclonal
Conjugate This XIAP antibody is un-conjugated
(6), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(163), (72), (53), (46), (28), (23), (13), (13), (9), (9), (3), (3), (2), (1), (1)
Pubmed 4 references available
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Product Details anti-XIAP Antibody

Target Details XIAP Application Details Handling References for anti-XIAP antibody (ABIN1003492) Images
Blocking Peptide Blocking peptide for this product available: ABIN1003918
Purification Affinity chromatography purified via peptide column.
Immunogen Rabbit polyclol XIAP antibody was raised against a synthetic peptide corresponding to 13 amino acids at the C-terminus of human XIAP (Genbank accession No. NP_001158).
Isotype IgG

Target Details XIAP

Product Details anti-XIAP Antibody Application Details Handling References for anti-XIAP antibody (ABIN1003492) Images back to top
Antigen
Alternative Name X-linked Inhibitor of Apoptosis Protein (XIAP Antibody Abstract)
Background Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and can be prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases. The X-chromosome linked inhibitor of apoptosis (XIAP) contains 3 baculoviral IAP repeat (BIR) motifs that are essential and sufficient for the binding and inhibition of caspases–3, –7, and –9. Upregulation of XIAP expression can protect cells from apoptosis induced by low level radiation, conversely, decreased XIAP expression by antisense targeting resulted in increased cell death following low level radiation. Two negative regulators, termed XAF-1 and Smac, can bind and inhibit XIAP activity.
Pathways Apoptosis, Caspase Cascade in Apoptosis, Transition Metal Ion Homeostasis

Application Details

Product Details anti-XIAP Antibody Target Details XIAP Handling References for anti-XIAP antibody (ABIN1003492) Images back to top
Application Notes XIAP antibody can be used for the detection of XIAP by Western blot at 0.5 to 2 µg/ml. (Optimal dilution should be determined by user.) Human kidney cell lysate can be used as positive control. Antibody can also be used for immunohistochemistry and ELISA and might be suited for other applications not tested so far. Anti-XIAP is human and mouse reactive.
Restrictions For Research Use only

Handling

Product Details anti-XIAP Antibody Target Details XIAP Application Details References for anti-XIAP antibody (ABIN1003492) Images back to top
Format Liquid
Buffer Antibody is supplied in PBS containing 0.02% sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Antibody can be stored at 4 °C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 myl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap.
Storage 4 °C
Expiry Date 12 months

References for anti-XIAP antibody (ABIN1003492)

Product Details anti-XIAP Antibody Target Details XIAP Application Details Handling Images back to top
Product cited in:

Schimmer: "Inhibitor of apoptosis proteins: translating basic knowledge into clinical practice." in: Cancer research, Vol. 64, Issue 20, pp. 7183-90, 2004

Holcik, Yeh, Korneluk, Chow: "Translational upregulation of X-linked inhibitor of apoptosis (XIAP) increases resistance to radiation induced cell death." in: Oncogene, Vol. 19, Issue 36, pp. 4174-7, 2000

Deveraux, Leo, Stennicke, Welsh, Salvesen, Reed: "Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases." in: The EMBO journal, Vol. 18, Issue 19, pp. 5242-51, 1999

Background publications

Deveraux, Takahashi, Salvesen, Reed: "X-linked IAP is a direct inhibitor of cell-death proteases." in: Nature, Vol. 388, Issue 6639, pp. 300-4, 1997