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beta Arrestin 1 Products

(Arrestin, beta 1 (ARRB1))

Categories

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011].

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Featured beta Arrestin 1 Categories

beta Arrestin 1 Antibodies

High quality antibodies with extensive validation data.

beta Arrestin 1 ELISA Kits

Reliable ELISA kits for a wide range of species.

beta Arrestin 1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended beta Arrestin 1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IF, IHC, IP, WB
Validations
  • (7)
Cat. No. ABIN3021265
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application FACS, ICC, IF, IHC, IP, WB
Validations
  • (8)
Cat. No. ABIN4903044
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application EIA, FACS, IF, IHC (p), WB
Validations
  • (4)
Cat. No. ABIN950521
Quantity 0.4 mL
Datasheet Datasheet

Recommended beta Arrestin 1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965022
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6953925
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5690830
Quantity 96 tests
Datasheet Datasheet

Recommended beta Arrestin 1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3089508
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3136291
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN2714947
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our beta Arrestin 1 products

Law, Zhang, Dragan, Postovit, Bhattacharya: "Nodal signals via β-arrestins and RalGTPases to regulate trophoblast invasion." in: Cellular signalling, Vol. 26, Issue 9, pp. 1935-42, (2014) (PubMed).

Zecchini, Madhu, Russell, Pértega-Gomes, Warren, Gaude, Borlido, Stark, Ireland-Zecchini, Rao, Scott, Boren, Massie, Asim, Brindle, Griffiths, Frezza, Neal, Mills: "Nuclear ARRB1 induces pseudohypoxia and cellular metabolism reprogramming in prostate cancer." in: The EMBO journal, Vol. 33, Issue 12, pp. 1365-82, (2014) (PubMed).

Bubnell, Pfister, Sapar, Rogers, Feinstein: "β2 adrenergic receptor fluorescent protein fusions traffic to the plasma membrane and retain functionality." in: PLoS ONE, Vol. 8, Issue 9, pp. e74941, (2013) (PubMed).

Li, Alemayehu, Aziziyeh, Pape, Pampillo, Postovit, Mills, Babwah, Bhattacharya: "Beta-arrestin/Ral signaling regulates lysophosphatidic acid-mediated migration and invasion of human breast tumor cells." in: Molecular cancer research : MCR, Vol. 7, Issue 7, pp. 1064-77, (2009) (PubMed).

Hüttenrauch, Pollok-Kopp, Oppermann: "G protein-coupled receptor kinases promote phosphorylation and beta-arrestin-mediated internalization of CCR5 homo- and hetero-oligomers." in: The Journal of biological chemistry, Vol. 280, Issue 45, pp. 37503-15, (2005) (PubMed).

Dalle, Imamura, Rose, Worrall, Ugi, Hupfeld, Olefsky: "Insulin induces heterologous desensitization of G-protein-coupled receptor and insulin-like growth factor I signaling by downregulating beta-arrestin-1." in: Molecular and cellular biology, Vol. 22, Issue 17, pp. 6272-85, (2002) (PubMed).

Imamura, Huang, Dalle, Ugi, Usui, Luttrell, Miller, Lefkowitz, Olefsky: "beta -Arrestin-mediated recruitment of the Src family kinase Yes mediates endothelin-1-stimulated glucose transport." in: The Journal of biological chemistry, Vol. 276, Issue 47, pp. 43663-7, (2001) (PubMed).

DeFea, Zalevsky, Thoma, Déry, Mullins, Bunnett: "beta-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2." in: The Journal of cell biology, Vol. 148, Issue 6, pp. 1267-81, (2000) (PubMed).

Gurevich, Dion, Onorato, Ptasienski, Kim, Sterne-Marr, Hosey, Benovic: "Arrestin interactions with G protein-coupled receptors. Direct binding studies of wild type and mutant arrestins with rhodopsin, beta 2-adrenergic, and m2 muscarinic cholinergic receptors." in: The Journal of biological chemistry, Vol. 270, Issue 2, pp. 720-31, (1995) (PubMed).

Attramadal, Arriza, Aoki, Dawson, Codina, Kwatra, Snyder, Caron, Lefkowitz: "Beta-arrestin2, a novel member of the arrestin/beta-arrestin gene family." in: The Journal of biological chemistry, Vol. 267, Issue 25, pp. 17882-90, (1992) (PubMed).

Synonyms and alternative names related to beta Arrestin 1

arrestin beta 1 (ARRB1), arrestin, beta 1 (arrb1), arrestin beta 1 L homeolog (arrb1.L), beta-arrestin 1 (CpipJ_CPIJ016988), beta-arrestin 1 (CpipJ_CPIJ017114), putative beta-arrestin 1 (Smp_122900), putative beta-arrestin 1 (Smp_126080), putative beta-arrestin 1 (Smp_176980), putative beta-arrestin 1 (Smp_152290), arrestin, beta 1 (Arrb1), arrestin beta 1 (Arrb1), 1200006I17Rik, arb1, ARB1, arr1, ARR1, arrb1, AW208571, barr1, BARRES, betaarr1, G430100A01Rik, MGC83787

Protein level used designations for beta Arrestin 1

  • arrestin, beta 1
  • arrestin 1
  • beta-arrestin 1
  • arrestin beta 1
  • beta-arrestin-1-like
  • arrestin beta-1
  • beta-arrestin-1
  • beta-arrestin1
  • arrestin 2
  • arrestin-2
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