Calpain S1 Products
(Calpain, Small Subunit 1 (CAPNS1))
Categories
Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. This gene encodes a small subunit common to both calpain I and II and is associated with myotonic dystrophy. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008].
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Featured Calpain S1 Categories
Calpain S1 Antibodies
High quality antibodies with extensive validation data.
Calpain S1 ELISA Kits
Reliable ELISA kits for a wide range of species.
Calpain S1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Calpain S1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF, IHC (p), RNAi
Validations
- (3)
- (8)
Cat. No.
ABIN560162
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7441262
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (1)
- (4)
Cat. No.
ABIN6137928
Quantity
100 μL
Datasheet
Datasheet
Recommended Calpain S1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6954303
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6954304
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6954305
Quantity
96 tests
Datasheet
Datasheet
Recommended Calpain S1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122104
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348004
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348002
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our Calpain S1 products
: "Calpain and AR-V7: Two potential therapeutic targets to overcome acquired docetaxel resistance in castration-resistant prostate cancer cells." in: Oncology reports, Vol. 37, Issue 6, pp. 3651-3659, (2018) (PubMed).: "Piperine inhibits ABCA1 degradation and promotes cholesterol efflux from THP-1-derived macrophages." in: Molecular nutrition & food research, (2016) (PubMed).
: "Differential proteomic analysis of caveolin-1 KO cells reveals Sh2b3 and Clec12b as novel interaction partners of caveolin-1 and Capns1 as a potential mediator of caveolin-1-induced apoptosis." in: The Analyst, Vol. 138, Issue 22, pp. 6986-96, (2013) (PubMed).
: "Overexpression of a minimal domain of calpastatin suppresses IL-6 production and Th17 development via reduced NF-?B and increased STAT5 signals." in: PLoS ONE, Vol. 6, Issue 10, pp. e27020, (2011) (PubMed).
: "The calpain inhibitor calpeptin prevents bleomycin-induced pulmonary fibrosis in mice." in: Clinical and experimental immunology, Vol. 162, Issue 3, pp. 560-7, (2010) (PubMed).
: "Vitamin E and C supplementation does not ameliorate muscle dysfunction after anterior cruciate ligament surgery." in: Free radical biology & medicine, Vol. 47, Issue 11, pp. 1611-8, (2009) (PubMed).
: "Deregulated repression of c-Jun provides a potential link to its role in tumorigenesis." in: Cell cycle (Georgetown, Tex.), Vol. 3, Issue 2, pp. 111-3, (2004) (PubMed).
: "AP-1 in cell proliferation and survival." in: Oncogene, Vol. 20, Issue 19, pp. 2390-400, (2001) (PubMed).
: "Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation." in: Nature genetics, Vol. 21, Issue 3, pp. 326-9, (1999) (PubMed).
: "c-Jun regulates cell cycle progression and apoptosis by distinct mechanisms." in: The EMBO journal, Vol. 18, Issue 1, pp. 188-97, (1999) (PubMed).
Synonyms and alternative names related to Calpain S1
calpain small subunit 1 (CAPNS1), calpain, small subunit 1 (Capns1), calpain, small subunit 1 L homeolog (capns1.L), calpain small subunit 1 (Capns1), calpain, small subunit 1 a (capns1a), 30K, CALPAIN4, CANP, CANPS, Capa-4, Capa4, CAPN4, Capn4, CAPNS1, capns1, cb616, CDPS, CSS1, D7Ertd146e, MGC84330, wu:fb81g08, wu:fl09e04, zgc:110603Protein level used designations for Calpain S1
- CANP small subunit
- calcium-activated neutral proteinase small subunit
- calcium-dependent protease small subunit 1
- calcium-dependent protease, small subunit
- calpain 4, small subunit (30K)
- calpain regulatory subunit
- calpain small subunit 1
- calpain, small polypeptide
- CDPS
- CSS1
- calpain 4
- calpain, small subunit 1
- calpain I light subunit
- calpain II small subunit
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