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CDKL5 Products

(Cyclin-Dependent Kinase-Like 5 (CDKL5))

Categories

This gene is a member of Ser/Thr protein kinase family and encodes a phosphorylated protein with protein kinase activity. Mutations in this gene have been associated with X-linked infantile spasm syndrome (ISSX), also known as X-linked West syndrome, and Rett syndrome (RTT). Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008].

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Featured CDKL5 Categories

CDKL5 Antibodies

High quality antibodies with extensive validation data.

CDKL5 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CDKL5 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN6260727
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN391362
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN563054
Quantity 100 μg
Datasheet Datasheet

Recommended CDKL5 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1349001
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Baculovirus infected Insect Cells, Insect cells (Sf9)
Validations
Cat. No. ABIN6699778
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our CDKL5 products

Ricciardi, Ungaro, Hambrock, Rademacher, Stefanelli, Brambilla, Sessa, Magagnotti, Bachi, Giarda, Verpelli, Kilstrup-Nielsen, Sala, Kalscheuer, Broccoli: "CDKL5 ensures excitatory synapse stability by reinforcing NGL-1-PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons." in: Nature cell biology, Vol. 14, Issue 9, pp. 911-23, (2012) (PubMed).

Kalscheuer, Tao, Donnelly, Hollway, Schwinger, Kübart, Menzel, Hoeltzenbein, Tommerup, Eyre, Harbord, Haan, Sutherland, Ropers, Gécz: "Disruption of the serine/threonine kinase 9 gene causes severe X-linked infantile spasms and mental retardation." in: American journal of human genetics, Vol. 72, Issue 6, pp. 1401-11, (2003) (PubMed).

Barbara, Wrana, Letarte: "Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily." in: The Journal of biological chemistry, Vol. 274, Issue 2, pp. 584-94, (1999) (PubMed).

Li, Sorensen, Brooke, Urness, Davis, Taylor, Boak, Wendel: "Defective angiogenesis in mice lacking endoglin." in: Science (New York, N.Y.), Vol. 284, Issue 5419, pp. 1534-7, (1999) (PubMed).

Bellón, Corbí, Lastres, Calés, Cebrián, Vera, Cheifetz, Massague, Letarte, Bernabéu: "Identification and expression of two forms of the human transforming growth factor-beta-binding protein endoglin with distinct cytoplasmic regions." in: European journal of immunology, Vol. 23, Issue 9, pp. 2340-5, (1993) (PubMed).

Gougos, Letarte: "Primary structure of endoglin, an RGD-containing glycoprotein of human endothelial cells." in: The Journal of biological chemistry, Vol. 265, Issue 15, pp. 8361-4, (1990) (PubMed).

Synonyms and alternative names related to CDKL5

cyclin dependent kinase like 5 (CDKL5), cyclin dependent kinase like 5 (cdkl5), cyclin-dependent kinase-like 5 (Cdkl5), BC038161, EIEE2, issx, ISSX, stk9, STK9, Stk9

Protein level used designations for CDKL5

  • cyclin-dependent kinase-like 5
  • cyclin-dependent kinase-like 5-like
  • cyclin dependent kinase 5 transcript
  • serine/threonine kinase 9
  • serine/threonine-protein kinase 9
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