anti-Human MYBL2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended MYBL2 Antibody

Antigen
V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2) Antibodies
  • MYBL2
  • bmyb
  • b-myb
  • B-Myb
  • Bmyb
  • B-MYB
  • BMYB
  • myb1
  • MYB proto-oncogene like 2
  • v-myb avian myeloblastosis viral oncogene homolog-like 2b
  • myeloblastosis oncogene-like 2
  • MYB proto-oncogene like 2 S homeolog
  • MYBL2
  • mybl2
  • mybl2b
  • Mybl2
  • mybl2.S
Epitope
AA 1-17, N-Term
25
16
15
9
9
6
5
4
4
3
3
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Rat (Rattus)
116
87
77
10
8
7
6
6
5
5
3
2
1
1
Host
Rabbit
101
17
11
Clonality
Polyclonal
Conjugate
This MYBL2 antibody is un-conjugated
6
4
4
4
4
4
4
4
4
2
2
2
2
2
1
1
1
Application
Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
81
53
29
26
12
11
6
5
5
2
1
Options

Available images

Catalog No. ABIN3044010
$ 280.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
19 ABIN3029533 ICC IHC (p) WB Rabbit IgG N-Term Polyclonal 0
10 ABIN6749786 IHC IHC (p) WB Rabbit IgG N-Term Polyclonal 0
9.734666 ABIN4282566 IHC IHC (p) WB Rabbit IgG Polyclonal 0
1 ABIN2625857 ICC IHC IHC (p) WB Rabbit IgG AA 1-17 Polyclonal 0
1 ABIN1711463 IHC (p) WB HRP Rabbit IgG pSer577 Polyclonal 0
1 ABIN1711464 IHC (p) WB HRP Rabbit IgG pThr487 Polyclonal 0
1 ABIN1700447 IHC (p) WB Biotin Rabbit IgG pThr487 Polyclonal 0
1 ABIN1700446 IHC (p) WB Biotin Rabbit IgG pSer577 Polyclonal 0
1 ABIN1713949 IF (p) IHC (p) WB Rabbit IgG pThr487 Polyclonal 0
1 ABIN1713948 IF (p) IHC (p) WB Rabbit IgG pSer577 Polyclonal 0
1 ABIN1915473 IF IHC IHC (p) IP Rabbit IgG AA 250-300 Polyclonal 0
1 ABIN1915475 IF IHC IHC (p) Rabbit IgG AA 450-500 Polyclonal 0
1 ABIN1915474 IF IHC IHC (p) IP Rabbit IgG AA 450-500 Polyclonal 0

General

Antigen V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2) Antibodies
Epitope AA 1-17, N-Term
(25), (16), (15), (9), (9), (6), (5), (4), (4), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Rat (Rattus)
(116), (87), (77), (10), (8), (7), (6), (6), (5), (5), (3), (2), (1), (1)
Host Rabbit
(101), (17), (11)
Clonality
Polyclonal
Conjugate This MYBL2 antibody is un-conjugated
(6), (4), (4), (4), (4), (4), (4), (4), (4), (2), (2), (2), (2), (2), (1), (1), (1)
Application Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(81), (53), (29), (26), (12), (11), (6), (5), (5), (2), (1)
Pubmed 1 reference available
Supplier

Product Details anti-MYBL2 Antibody

Target Details MYBL2 Application Details Handling References for anti-MYBL2 antibody (ABIN3044010) Images
Purpose Rabbit IgG polyclonal antibody for Myb-related protein B(MYBL2) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
Sequence MSRRTRCEDL DELHYQD
Cross-Reactivity (Details) Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
Characteristics Rabbit IgG polyclonal antibody for Myb-related protein B(MYBL2) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
Gene Name: v-myb myeloblastosis viral oncogene homolog(avian)-like 2
Protein Name: Myb-related protein B
Purification Immunogen affinity purified.
Immunogen A synthetic peptide corresponding to a sequence at the N-terminus of human B MyB(1-17aa MSRRTRCEDLDELHYQD), identical to the related mouse sequence and different from the related rat sequence by two amino acids.
Isotype IgG
Plasmids, Primers & others

Target Details MYBL2

Product Details anti-MYBL2 Antibody Application Details Handling References for anti-MYBL2 antibody (ABIN3044010) Images back to top
Antigen
Alternative Name MYBL2 (MYBL2 Antibody Abstract)
Background MYBL2(V-MYB avian myeloblastosis viral oncogene homolog-like 2), also called MYB-RELATED GENE BMYB, is a protein that in humans is encoded by the MYBL2 gene. The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. Barletta et al.(1991) assigned the MYBL2 gene to chromosome Xq13. However, Noben-Trauth et al.(1996) demonstrated that this assignment was an error. Using mouse Mybl2 cDNA clones as probes, they assigned Mybl2 in an interspecific backcross panel to distal mouse chromosome 2. Using human cDNA probes in combination with fluorescence in situ hybridization analysis, they localized MYBL2 to chromosome 20q13.1, a region that is commonly deleted in myeloid disorders and shows high homology of synteny to mouse chromosome 2. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Transcript variants may exist for this gene, but their full-length natures have not been determined.

Synonyms: B-Myb antibody|BMyB antibody|MGC15600 antibody|MYB L2 antibody|Myb related protein B antibody|Myb-like protein 2 antibody|Myb-related protein B antibody|MybB antibody|MYBB_HUMAN antibody|MYBL 2 antibody|MYBL2 antibody|v myb avian myeloblastosis viral oncogene homolog like 2 antibody|v myb myeloblastosis viral oncogene homolog(avian) like 2 antibody|v myb myeloblastosis viral oncogene homolog like 2 antibody
UniProt P10244
Pathways Cell Division Cycle, Mitotic G1-G1/S Phases, Chromatin Binding

Application Details

Product Details anti-MYBL2 Antibody Target Details MYBL2 Handling References for anti-MYBL2 antibody (ABIN3044010) Images back to top
Application Notes WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, The detection limit for MYBL2 is approximately 0.5 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
Comment

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

Restrictions For Research Use only

Handling

Product Details anti-MYBL2 Antibody Target Details MYBL2 Application Details References for anti-MYBL2 antibody (ABIN3044010) Images back to top
Format Lyophilized
Reconstitution Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
Concentration 500 μg/mL
Buffer Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
Preservative Thimerosal (Merthiolate), Sodium azide
Precaution of Use This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Expiry Date 12 months

References for anti-MYBL2 antibody (ABIN3044010)

Product Details anti-MYBL2 Antibody Target Details MYBL2 Application Details Handling Images back to top
Product cited in:

Tao, Wang, Xu, Li, Li, Xu, Fang, Li, Qian, Li, Li, Wu, Ren, Du, Lu, Feng, Wang, He, Hu, Pan: "Molecular mechanism of G1 arrest and cellular senescence induced by LEE011, a novel CDK4/CDK6 inhibitor, in leukemia cells." in: Cancer cell international, Vol. 17, pp. 35, 2017

Images

Product Details anti-MYBL2 Antibody Target Details MYBL2 Application Details Handling References for anti-MYBL2 antibody (ABIN3044010) back to top
Supplier Images
Western Blotting (WB) image for anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2) (AA 1-17), (N-Term) antibody (ABIN3044010) Anti-B MyB antibody, Western blotting Lane 1: Rat Spleen Tissue Lysate Lane 2: Rat Th...
Immunohistochemistry (IHC) image for anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2) (AA 1-17), (N-Term) antibody (ABIN3044010) Anti-B MyB antibody, ICC ICC: A549 Cell
Western Blotting (WB) image for anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2) (AA 1-17), (N-Term) antibody (ABIN3044010) Lane 3: Recombinant Human MYBL2 Protein 2.5ng
Immunohistochemistry (IHC) image for anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2) (AA 1-17), (N-Term) antibody (ABIN3044010) Anti-B MyB antibody, IHC(P) IHC(P): Human Tonsil Tissue
Immunohistochemistry (IHC) image for anti-V-Myb Myeloblastosis Viral Oncogene Homolog (Avian)-Like 2 (MYBL2) (AA 1-17), (N-Term) antibody (ABIN3044010) Anti-B MyB antibody, IHC(P) IHC(P): Rat Brain Tissue