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Human MAZ Protein expressed in Wheat germ - ABIN1310456
Maloney, Stearman, Bull, Calabrese, Tripp-Addison, Wick, Broeckel, Robbins, Wheeler, Cogan, Loyd: Loss-of-function thrombospondin-1 mutations in familial pulmonary hypertension. in American journal of physiology. Lung cellular and molecular physiology 2012
MAZ can promote the invasion and metastasis of hepatocellular carcinoma by inducing epithelial-mesenchymal transition (EMT (show ITK Proteins)).
A quantitative association between MAZ-autoantibody optical density on ELISA and the cumulative inflammatory burden of atherosclerosis on (18)F-FDG (show SMUG1 Proteins) PET/CT could be shown, suggesting MAZ-Ab as potential biomarker for atherosclerotic disease.
The data indicate that MAZ is essential to bypass MYB (show MYB Proteins) promoter repression by RB family members and to induce MYB (show MYB Proteins) expression.
MAZ/FOXF2 (show FOXF2 Proteins) axis can promote the proliferation of basal like breast cancer cells and suppress disease progression.
Data suggest that long noncoding RNA PlncRNA1 and microRNA miR (show MLXIP Proteins)-34c bound together to regulate the expressions of MAZ, ZO-1 (show TJP1 Proteins) and occludin (show OCLN Proteins).
a transcriptional factor, Myc-associated zinc finger protein (MAZ), plays an important role in ADAM10 (show ADAM10 Proteins) transcription in response to CT-1 (show CTF1 Proteins) in neural stem/progenitor cells.
Akt (show AKT1 Proteins) phosphorylates MAZ at Thr385, and the phosphorylated MAZ is released from the p53 (show TP53 Proteins) promoter, leading to transcriptional activation of p53 (show TP53 Proteins).
Myc-associated zinc-finger protein (MAZ) was identified as a direct target of miR (show MLXIP Proteins)-449a, mediating the tumor-suppressive effects.
Studies show a feed-forward regulatory pathway in breast cancer cells where SAF-1 acts as a transcriptional inducer of Ras which in turn increases DNA-binding and transcriptional activities of SAF-1 which in turn, increases transcription of Ras.
In conclusion, our present study indicated that miR (show MLXIP Proteins)-34c regulated the permeability of BTB via MAZ-mediated expression changes of ZO-1 (show TJP1 Proteins), occludin (show OCLN Proteins), and claudin-5 (show CLDN5 Proteins).
myc (show MYC Proteins)-associated zinc finger (MAZ) protein was essential for HIF2alpha (show EPAS1 Proteins) activation of the Cav1 (show CAV1 Proteins) promoter.
HNF4 (show HNF4A Proteins)-1 and MAZ-1 regulate the expression of Rho-GDIgamma and contribute to the differentiation of neural stem cells.
These data support a transcription mechanism for murine KRAS that involves MAZ, PARP-1 (show PARP1 Proteins) and duplex-quadruplex conformational changes in the promoter G-rich nuclease (show DCLRE1C Proteins) hypersensitive element.
SAF-1 induces VEGF (show VEGFA Proteins) transcription by directly binding to its promoter; markedly higher levels of SAF-1 interaction with the VEGF (show VEGFA Proteins) promoter was detected in the cartilage tissues of arthritic mice as well as human osteoarthritic patients.
These findings are consistent with a previously unrecognized role for MAZ in muscle gene regulation.
May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the MYC promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors.
, myc-associated zinc finger protein
, purine-binding transcription factor
, serum amyloid A activating factor 1
, serum amyloid A activating factor 2
, serum amyloid A-activating factor-1
, transcription factor Zif87
, zinc finger protein 801
, zinc-finger protein, 87 kilodaltons
, serum amyloid A-activating factor SAF-1