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Cone-Rod Homeobox Products

(Cone-Rod Homeobox (CRX))

Categories

The protein encoded by this gene is a photoreceptor-specific transcription factor which plays a role in the differentiation of photoreceptor cells. This homeodomain protein is necessary for the maintenance of normal cone and rod function. Mutations in this gene are associated with photoreceptor degeneration, Leber congenital amaurosis type III and the autosomal dominant cone-rod dystrophy 2. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008].

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Featured Cone-Rod Homeobox Categories

Cone-Rod Homeobox Antibodies

High quality antibodies with extensive validation data.

Cone-Rod Homeobox Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Cone-Rod Homeobox Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (10)
  • (4)
Cat. No. ABIN560473
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, RNAi
Validations
  • (1)
  • (4)
Cat. No. ABIN560472
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7148440
Quantity 100 μL
Datasheet Datasheet

Recommended Cone-Rod Homeobox ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6214128
Quantity 96 tests
Datasheet Datasheet

Recommended Cone-Rod Homeobox Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1350411
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350415
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3078261
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Cone-Rod Homeobox products

Khan, Walters, Li, Thomas, Miller, Zhang, Sciallis, Liu, Dlouhy, Fort, Archer, Demirci, Dou, Rao: "Characterization and pharmacologic targeting of EZH2, a fetal retinal protein and epigenetic regulator, in human retinoblastoma." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 95, Issue 11, pp. 1278-90, (2015) (PubMed).

Machalińska, Rogińska, Pius-Sadowska, Kawa, Paczkowska, Rudnicki, Lejkowska, Baumert, Wiszniewska, Machaliński: "Neuroprotective and antiapoptotic activity of lineage-negative bone marrow cells after intravitreal injection in a mouse model of acute retinal injury." in: Stem cells international, Vol. 2015, pp. 620364, (2015) (PubMed).

Reichman, Goureau: "Production of Retinal Cells from Confluent Human iPS Cells." in: Methods in molecular biology (Clifton, N.J.), Vol. 1357, pp. 339-51, (2015) (PubMed).

Tran, Zhang, Zhang, Huecker, Hennig, Chen: "Mechanistically distinct mouse models for CRX-associated retinopathy." in: PLoS genetics, Vol. 10, Issue 2, pp. e1004111, (2014) (PubMed).

Jayaram, Jones, Eastlake, Cottrill, Becker, Wiseman, Khaw, Limb: "Transplantation of photoreceptors derived from human Muller glia restore rod function in the P23H rat." in: Stem cells translational medicine, Vol. 3, Issue 3, pp. 323-33, (2014) (PubMed).

Reichman, Terray, Slembrouck, Nanteau, Orieux, Habeler, Nandrot, Sahel, Monville, Goureau: "From confluent human iPS cells to self-forming neural retina and retinal pigmented epithelium." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 23, pp. 8518-23, (2014) (PubMed).

Xie, Zhang, Hashimoto, Tien, Chen, Ge, Yang: "Differentiation of retinal ganglion cells and photoreceptor precursors from mouse induced pluripotent stem cells carrying an Atoh7/Math5 lineage reporter." in: PLoS ONE, Vol. 9, Issue 11, pp. e112175, (2014) (PubMed).

Terrell, Xie, Workman, Mahato, Zelhof, Gebelein, Cook: "OTX2 and CRX rescue overlapping and photoreceptor-specific functions in the Drosophila eye." in: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 241, Issue 1, pp. 215-28, (2011) (PubMed).

Carr, Vugler, Yu, Semo, Coffey, Moss, Greenwood: "The expression of retinal cell markers in human retinal pigment epithelial cells and their augmentation by the synthetic retinoid fenretinide." in: Molecular vision, Vol. 17, pp. 1701-15, (2011) (PubMed).

Sakagami, Gan, Yang: "Distinct effects of Hedgehog signaling on neuronal fate specification and cell cycle progression in the embryonic mouse retina." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 21, pp. 6932-44, (2009) (PubMed).

Synonyms and alternative names related to Cone-Rod Homeobox

cone-rod homeobox (crx), cone-rod homeobox (CRX), cone-rod homeobox (Crx), cone-rod homeobox L homeolog (crx.L), cone-rod homeobox S homeolog (crx.S), cord2, CORD2, crd, CRD, CRX, crx, Crx1, LCA7, OTX3, otx5, otx5-A, otx5-b, otx5b, rx, Xotx5, Xotx5b

Protein level used designations for Cone-Rod Homeobox

  • homeobox protein otx5
  • orthodenticle homolog 5
  • cone-rod homeobox protein
  • crx gene for cone-rod homeobox protein
  • photoreceptor-specific cone-rod homeobox protein
  • cone-rod homeobox
  • cone-rod homeobox containing
  • homeobox protein otx5-B
  • XOtx5b
  • orthodenticle homolog 5-B
  • orthodenticle homeobox 3
  • homeobox protein otx5-A
  • orthodenticle homolog 5-A
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