DAZL Products
(Deleted in Azoospermia-Like (DAZL))
Categories
The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010].
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Featured DAZL Categories
DAZL Antibodies
High quality antibodies with extensive validation data.
DAZL ELISA Kits
Reliable ELISA kits for a wide range of species.
DAZL Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended DAZL Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (5)
Cat. No.
ABIN6139416
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN185441
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
Cat. No.
ABIN7149640
Quantity
100 μg
Datasheet
Datasheet
Recommended DAZL ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1129363
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1129364
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Chicken
Analytical Method
Validations
Cat. No.
ABIN1129362
Quantity
96 tests
Datasheet
Datasheet
Recommended DAZL Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1777509
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3078670
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3123297
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our DAZL products
: "Decrease in male mouse fertility by hydrogen sulfide and/or ammonia can Be inheritable." in: Chemosphere, Vol. 194, pp. 147-157, (2018) (PubMed).: "A PAX5-OCT4-PRDM1 developmental switch specifies human primordial germ cells." in: Nature cell biology, Vol. 20, Issue 6, pp. 655-665, (2018) (PubMed).
: "Treosulfan induces distinctive gonadal toxicity compared with busulfan." in: Oncotarget, Vol. 9, Issue 27, pp. 19317-19327, (2018) (PubMed).
: "Abnormal gametogenesis induced by p53 deficiency promotes tumor progression and drug resistance." in: Cell discovery, Vol. 4, pp. 54, (2018) (PubMed).
: "Germ stem cells are active in postnatal mouse ovary under physiological conditions." in: Molecular human reproduction, Vol. 22, Issue 5, pp. 316-28, (2016) (PubMed).
: "Dexrazoxane exacerbates doxorubicin-induced testicular toxicity." in: Reproduction (Cambridge, England), Vol. 150, Issue 4, pp. 357-66, (2015) (PubMed).
: "Human germ cell formation in xenotransplants of induced pluripotent stem cells carrying X chromosome aneuploidies." in: Scientific reports, Vol. 4, pp. 6432, (2014) (PubMed).
: "The human testis-specific proteome defined by transcriptomics and antibody-based profiling." in: Molecular human reproduction, Vol. 20, Issue 6, pp. 476-88, (2014) (PubMed).
: "Isolation, genetic manipulation, and transplantation of canine spermatogonial stem cells: progress toward transgenesis through the male germ-line." in: Reproduction (Cambridge, England), Vol. 146, Issue 1, pp. 75-90, (2013) (PubMed).
: "Opposing effects of retinoic acid and FGF9 on Nanos2 expression and meiotic entry of mouse germ cells." in: Journal of cell science, Vol. 123, Issue Pt 6, pp. 871-80, (2010) (PubMed).
Synonyms and alternative names related to DAZL
deleted in azoospermia like (DAZL), deleted in azoospermia-like (DAZL), deleted in azoospermia-like (dazl), deleted in azoospermia-like (Dazl), deleted in azoospermia-like L homeolog (dazl.L), deleted in azoospermia like (dazl), deleted in azoospermia like (Dazl), Daz-like, DAZH, dazh, Dazh, DAZL, dazl-a, dazl-B, DAZL1, dazl1, Dazl1, DAZLA, dazla, Dazla, SPGYLA, spgyla, Tpx-2, Tpx2, XdazlProtein level used designations for DAZL
- DAZ homolog
- DAZ-like autosomal
- SPGY-like-autosomal
- deleted in azoospermia-like 1
- germline specific RNA binding protein
- spermatogenesis gene on the Y-like autosomal
- deleted in azoospermia-like
- DAZ-like protein
- deleted in azoospermia-like protein
- deleted in azoospermia protein 3
- xtdazl
- DAZ-like protein A
- DAZ-like protein B
- Deleted in azoospermia-like-B
- deleted in azoospermia-like-A
- xDazl-A
- xDazl-B
- Deleted in azoospermia-like 1
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