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(Deleted in Azoospermia 2 (DAZ2))

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This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications\\\\; one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat\\\\; the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified\\\\; this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains one copy of the 10.8 kb repeat. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

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Featured DAZ2 Categories

DAZ2 Antibodies

High quality antibodies with extensive validation data.

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Synonyms and alternative names related to DAZ2

deleted in azoospermia 2 (DAZ2), deleted in azoospermia protein 2 (LOC738583), DAZ2, pDP1678

Protein level used designations for DAZ2

  • deleted in azoospermia protein 2
  • deleted in azoospermia 2
  • deleted in azoospermia 4
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