anti-Mouse (Murine) ADCY4 antibody for Enzyme Immunoassay

Recommended ADCY4 Antibody (supplied by: Log in to see )

Antigen
Adenylate Cyclase 4 (ADCY4) Antibodies
  • ADCY4
  • mKIAA4004
  • AC4
  • adenylate cyclase 4
  • ADCY4
  • Adcy4
Reactivity
Human, Mouse (Murine), Rat (Rattus)
64
38
37
Host
Rabbit
67
Clonality
Polyclonal
Conjugate
This ADCY4 antibody is un-conjugated
4
4
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
48
34
17
13
12
5
4
4
3
1
1
1
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Catalog No. ABIN317941
$ 390.50
Plus shipping costs $45.00

General

Antigen Adenylate Cyclase 4 (ADCY4) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(64), (38), (37)
Host Rabbit
(67)
Clonality
Polyclonal
Conjugate This ADCY4 antibody is un-conjugated
(4), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(48), (34), (17), (13), (12), (5), (4), (4), (3), (1), (1), (1)
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Product Details anti-ADCY4 Antibody

Target Details ADCY4 Application Details Handling Images
Specificity A Cyclase IV antibody detects endogenous levels of A Cyclase IV protein.(region surrounding Leu226)
Purification Affinity chromatography
Plasmids, Primers & others

Target Details ADCY4

Product Details anti-ADCY4 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Adenylate Cyclase Type 4 (ADCY4 Antibody Abstract)
Background Adenylyl cyclases function to convert ATP to cyclic AMP in response to activation by a variety of hormones, neurotransmitters and other regulatory molecules. Cyclic AMP, in turn, activates several other target molecules to control a broad range of diverse phenomena such as metabolism, gene transcription and memory. Adenylyl cyclases respond to receptor-initiated signals, mediated by the Gs and Gi heterotrimeric G proteins. The binding of an agonist to a Gs-coupled receptor catalyzes the exchange of GDP (bound to Gα s) for GTP, the dissociation of GTP-Gα s from Gβγ and Gα s-mediated activation of adenylyl cyclase. Adenylyl cyclase IV (AC IV) and IX mRNA are expressed in all kidney nephron segments. AC IV exhibits moderate staining in type II and type IV fibrocytes in rat cochlea and immunoreactivity is also observed in type I fibrocytes. Activation of the D2 dopaminergic and m4 muscarine receptors inhibits the activity of adenylyl cyclase isozymes I, V, VI and VIII, whereas type II, IV and VII are stimulated and type III is not affected.Synonyms: ADCY4, ATP pyrophosphate-lyase 4, Adenylate cyclase type IV, Adenylyl cyclase 4
Molecular Weight approx. 120 kDa
Gene ID 196883
NCBI Accession NP_001185497
UniProt Q8NFM4
Pathways EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma

Application Details

Product Details anti-ADCY4 Antibody Target Details ADCY4 Handling Images back to top
Application Notes ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-ADCY4 Antibody Target Details ADCY4 Application Details Images back to top
Concentration 1,0 mg/mL
Buffer Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-ADCY4 Antibody Target Details ADCY4 Application Details Handling back to top
Supplier Images
 image for anti-Adenylate Cyclase 4 (ADCY4) antibody (ABIN317941) anti-Adenylate Cyclase 4 (ADCY4) antibody