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FOXN1 Products

(Forkhead Box N1 (FOXN1))

Categories

The protein encoded by this gene is part of the forkhead family or 'winged-helix' transcription factors that are important in developmental processes, immune system regulation, metabolism, cancer and aging. This gene family has over 100 members, subdivided into classes (A-Q) based on phylogeny. The encoded protein is proposed to regulate development of the thymus and differentiation of keratinocytes. Mutations in this gene cause severe primary T-cell immunodeficiency and congenital alopecia. In mouse mutations of this gene underlie the phenotype of the nude mouse, which has been widely used as a model system in oncology, immunology, dermatology, and transplantation studies. In humans mutations in this gene have been correlated with T-cell immunodeficiency, the skin disorder congenital alopecia, and nail dystrophy. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Apr 2013].

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Featured FOXN1 Categories

FOXN1 Antibodies

High quality antibodies with extensive validation data.

FOXN1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended FOXN1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, FACS, IF (cc), IF (p), IHC (fro), IHC (p), WB
Validations
  • (1)
  • (4)
Cat. No. ABIN1387592
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, WB
Validations
  • (3)
Cat. No. ABIN7153070
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN185069
Quantity 100 μg
Datasheet Datasheet

Recommended FOXN1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3092648
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3135432
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1354377
Quantity 2 μg
Datasheet Datasheet

Latest Publications for our FOXN1 products

Volpi, Yamazaki, Brauer, van Rooijen, Hayashida, Slavotinek, Sun Kuehn, Di Rocco, Rivolta, Bortolomai, Du, Felgentreff, Ott de Bruin, Hayashida, Freedman, Marcovecchio, Capuder, Rath, Luche, Hagedorn et al.: "EXTL3 mutations cause skeletal dysplasia, immune deficiency, and developmental delay. ..." in: The Journal of experimental medicine, Vol. 214, Issue 3, pp. 623-637, (2017) (PubMed).

Schlake, Schorpp, Maul-Pavicic, Malashenko, Boehm: "Forkhead/winged-helix transcription factor Whn regulates hair keratin gene expression: molecular analysis of the nude skin phenotype." in: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 217, Issue 4, pp. 368-76, (2000) (PubMed).

Synonyms and alternative names related to FOXN1

forkhead box N1 (FOXN1), forkhead box N1 (foxn1), forkhead box N1 (foxN1), forkhead box protein N1 (LOC100125524), forkhead box N1 (Foxn1), D11Bhm185e, Fkh19, FKHL20, foxN, FOXN1, foxN1, foxn1, HFH-11, Hfh11, nu, nude, Rnu, RONU, WHN, Whn, whnb

Protein level used designations for FOXN1

  • forkhead box protein N1
  • forkhead box N1
  • forkhead box N protein
  • forkhead box protein N1-like
  • transcription factor Forkhead box protein N1
  • Rowett nude
  • winged helix nude
  • winged-helix nude
  • winged-helix transcription factor nude
  • HNF-3/forkhead homolog 11
  • hepatocyte nuclear factor 3 forkhead homolog 11
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