GABRD Products
(GABA A Receptor delta (GABRD))
Categories
Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].
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Featured GABRD Categories
GABRD Antibodies
High quality antibodies with extensive validation data.
GABRD Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GABRD Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Cow, Dog, Human, Mouse, Rabbit
Application
WB, IHC
Validations
- (5)
Cat. No.
ABIN2792262
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS, IHC (p)
Validations
- (3)
Cat. No.
ABIN653247
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Rat
Application
WB, IHC (p)
Validations
- (3)
Cat. No.
ABIN5578576
Quantity
100 μL
Datasheet
Datasheet
Recommended GABRD ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6209852
Quantity
96 tests
Datasheet
Datasheet
Recommended GABRD Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN3080671
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN3133344
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
- (1)
Cat. No.
ABIN3109619
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our GABRD products
: "Maternal care-related differences in males and females rats' sensitivity to ethanol and the associations between the GABAergic system and steroids in males." in: Developmental psychobiology, Vol. 60, Issue 4, pp. 380-394, (2018) (PubMed).: "Alleviation of Mechanical Allodynia by 14,15-Epoxyeicosatrienoic Acid in a Central Poststroke Pain Model: Possible Role of Allopregnanolone and δ-Subunit-Containing Gamma-Aminobutyric Acid A ..." in: The journal of pain : official journal of the American Pain Society, (2018) (PubMed).
: "Strain-specific programming of prenatal ethanol exposure across generations." in: Alcohol (Fayetteville, N.Y.), Vol. 60, pp. 191-199, (2017) (PubMed).
: "Maternal care and affective behavior in female offspring: Implication of the neurosteroid/GABAergic system." in: Psychoneuroendocrinology, Vol. 76, pp. 29-37, (2016) (PubMed).
: "Alterations in Brain Inflammation, Synaptic Proteins, and Adult Hippocampal Neurogenesis during Epileptogenesis in Mice Lacking Synapsin2." in: PLoS ONE, Vol. 10, Issue 7, pp. e0132366, (2015) (PubMed).
: "Adolescent alcohol exposure alters GABAA receptor subunit expression in adult hippocampus." in: Alcoholism, clinical and experimental research, Vol. 38, Issue 11, pp. 2800-8, (2014) (PubMed).
: "Repeated intermittent alcohol exposure during the third trimester-equivalent increases expression of the GABA(A) receptor δ subunit in cerebellar granule neurons and delays motor development in rats." in: Neuropharmacology, Vol. 79, pp. 262-74, (2014) (PubMed).
: "Loss of Gabrd in CRH neurons blunts the corticosterone response to stress and diminishes stress-related behaviors." in: Psychoneuroendocrinology, Vol. 41, pp. 75-88, (2014) (PubMed).
: "Development of layer 1 neurons in the mouse neocortex." in: Cerebral cortex (New York, N.Y. : 1991), Vol. 24, Issue 10, pp. 2604-18, (2014) (PubMed).
: "Altered GABAA receptor expression and seizure threshold following acute ethanol challenge in mice lacking the RIIβ subunit of PKA." in: Neurochemical research, Vol. 39, Issue 6, pp. 1079-87, (2014) (PubMed).
Synonyms and alternative names related to GABRD
gamma-aminobutyric acid type A receptor delta subunit (GABRD), gamma-aminobutyric acid type A receptor delta subunit (Gabrd), gamma-aminobutyric acid (GABA) A receptor, subunit delta (Gabrd), AI853201, EIG10, EJM7, GABAA-RD, GABRD, GEFSP5Protein level used designations for GABRD
- gamma-aminobutyric acid (GABA) A receptor, delta
- gamma-aminobutyric acid receptor subunit delta-like
- GABA(A) receptor subunit delta
- GABA(A) receptor, delta
- GABA-A receptor, delta polypeptide
- gamma-aminobutyric acid receptor subunit delta
- GABA-A receptor delta-subunit
- GABAA receptor delta subunit
- gamma-aminobutyric acid A receptor, delta
- gamma-aminobutyric acid (GABA-A) receptor, subunit delta
- gamma-aminobutyric acid A receptor, delta
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