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Human Monoclonal HPSE2 Primary Antibody for ICC, FACS - ABIN438798
Bonner, Kerr-Conte, Gmyr, Queniat, Moerman, Thévenet, Beaucamps, Delalleau, Popescu, Malaisse, Sener, Deprez, Abderrahmani, Staels, Pattou: Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion. in Nature medicine 2015
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This gene encodes a heparanase enzyme. The encoded protein is a endoglycosidase that degrades heparin sulfate proteoglycans located on the extracellular matrix and cell surface. This protein may be involved in biological processes involving remodeling of the extracellular matrix including angiogenesis and tumor progression. Alternate splicing results in multiple transcript variants.
, heparanase 3
, heparanase-like protein
, inactive heparanase-2