anti-Mammalian CGRP antibody for Immunofluorescence

Recommended CGRP Antibody (supplied by: Log in to see )

Antigen
Calcitonin-Related Polypeptide alpha (CALCA) Antibodies
  • CALC1
  • CGRP
  • CGRP-I
  • CGRP1
  • CT
  • KC
  • CALC
  • CALCA
  • CALC3
  • ci-ct
  • calca
  • CA
  • CGRP-1
  • Calc
  • Calc1
  • Cgrp
  • Ct
  • Ctn
  • calcitonin
  • CAL6
  • Cal1
  • RATCAL6
  • CGRPI
  • calc
  • cgrp
  • zgc:92886
  • calcitonin related polypeptide alpha
  • calcitonin related polypeptide beta
  • calcitonin-related polypeptide alpha
  • calcitonin
  • calcitonin/calcitonin-related polypeptide, alpha
  • calcitonin gene-related peptide 2
  • CALCA
  • CALCB
  • ci-ct
  • calca
  • Calca
  • LOC100008771
Reactivity
Human, Mammalian, Rat (Rattus)
117
93
32
3
2
2
2
2
1
1
1
1
1
1
1
1
1
Host
Mouse
76
50
9
8
3
Clonality
Monoclonal
Conjugate
This CGRP antibody is un-conjugated
10
7
7
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
80
56
56
45
33
17
13
12
10
6
3
2
2
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Catalog No. ABIN5550808
$ 484.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN285696 IHC (fro) IF IHC (p) Rabbit IgG1 Log in to see Polyclonal 0

General

Antigen Calcitonin-Related Polypeptide alpha (CALCA) Antibodies
Reactivity Human, Mammalian, Rat (Rattus)
(117), (93), (32), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Host Mouse
(76), (50), (9), (8), (3)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CGRP antibody is un-conjugated
(10), (7), (7), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
(80), (56), (56), (45), (33), (17), (13), (12), (10), (6), (3), (2), (2), (1)
Supplier Log in to see

Product Details anti-CGRP Antibody

Target Details CGRP Application Details Handling Images
Specificity This antibody is specific for Calcitonin Gene Related Peptide. Also recognizes rat beta-CGRP and human alpha-CGRP (10-fold less sensitivity compared to rat alpha-CGRP). Suggested Positive Controls: Dorsal root ganglia, pancreas and gut.
Cross-Reactivity (Details) Species reactivity (expected):most Mammals.
Species reactivity (tested):Human and Rat.
Characteristics Synonyms: Calcitonin gene-related peptide I, Alpha-type CGRP, CALC1, CGRP-I
Purification Protein G Chromatography.
Clone 4901
Isotype IgG2a

Target Details CGRP

Product Details anti-CGRP Antibody Application Details Handling Images back to top
Antigen
Alternative Name CGRP / CALCA (CALCA Antibody Abstract)
Background Calcitonin Gene Related Peptide [CGRP] is a 37 amino acid peptide and is the most potent endogenous vasodilator currently known (Brain et al.,1985). CGRP is primarily produced in nervous tissue, however, its receptors are expressed throughout the body. CGRP is also strongly implicated in the vasodilatory effect of endogenous cannabinoid anandamide in the brain. This effect was found to be antagonized by capsazepine. CGRP is also currently a major target of research in regards to factors effecting the onset of migraine headaches (Edvinsson L., 2003). CGRP antibodies have been used successfully in Immunoneutralization (Wong et al., 1993)Synonyms: Alpha-type CGRP, CALC1, CGRP-I, Calcitonin gene-related peptide I
Gene ID 796
UniProt P06881
Pathways Hormone Activity, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, Feeding Behaviour

Application Details

Product Details anti-CGRP Antibody Target Details CGRP Handling Images back to top
Application Notes Immunocytochemistry: 1/50-1/100. Immunofluorescence and Immunohistochemistry: This antibody is an excellent tool forImmunohistochemistry and for multiple labeling immunofluorescence of peripheral tissuelike stomach, intestine, pancreas, sensory ganglia, and all the regions of the body that areinnervated by primary afferent neurons as well as central nervous tissue. Suggested Positive Controls: Dorsal root ganglia, pancreas and gut. Not recommended for Western blotting.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-CGRP Antibody Target Details CGRP Application Details Images back to top
Format Liquid
Buffer 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol
Storage -20 °C
Storage Comment Store the antibody undiluted (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Expiry Date 12 months