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|Antigen||Insulin-Like Growth Factor 2 (IGF2) Antibodies|
|Reactivity||Cow (Bovine), Human Alternatives|
|Conjugate||This IGF2 antibody is un-conjugated Alternatives|
Western Blotting (WB)
|Supplier||Log in to see|
Product Details anti-IGF2 AntibodyTarget Details IGF2 Application Details Handling Images
|Specificity||This antibody recognizes IGF-2.|
|Immunogen||Human Insulin-like Growth Factor-2 (Somatomedin A)|
|Plasmids, Primers & others|
Target Details IGF2Product Details anti-IGF2 Antibody Application Details Handling Images back to top
|Alternative Name||Insulin-Like Growth Factor II / IGF2 (IGF2 Antibody Abstract)|
|Background||Insulin-like growth factor II (also known as multiplication stimulating activity or MSA) and insulin-like growth factor I (IGF-I) belong to the family of insulin-like growth factors which are structurally homologous to proinsulin. Mature IGF-I and IGF-II are highly conserved and share approx imately 70 % amino acid sequence identity. Mouse IGF-II, a 67 amino acid protein, has a predicted molecular mass of approximately 7.4 kDa. Mouse and human IGF-II share 91 % sequence identity. Insulin-like growth factor II has autocrine, paracrine, and endocrine functions. It is a potent mitogenic growth factor that mediates growth-promoting activities in embryonic development. IGF-II binds the IGF-II receptor with high affinity. IGF-I and IGF II are expressed in many tissues and cell types. IGF-II is mitogenic for a variety of cultured cells including human or chicken fibroblasts, mouse 3T3 cells, normal rat kidney cells, and MCF-7 human breast carcinoma cells.Synonyms: IGF-II, Somatomedin-A|
|Pathways||Hormone Activity, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Activated T Cell Proliferation|
Application DetailsProduct Details anti-IGF2 Antibody Target Details IGF2 Handling Images back to top
Western blot: 1/1000-1/2000. Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-IGF2 Antibody Target Details IGF2 Application Details Images back to top
|Reconstitution||Restore in aqua bidest to initial volume.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store lyophilized at 2-8 °C and reconstituted at -20 °C.|