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HSD17B6 Products

(Hydroxysteroid (17-Beta) Dehydrogenase 6 (HSD17B6))

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The protein encoded by this gene has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. This gene is a member of the retinol dehydrogenase family. Transcript variants utilizing alternative polyadenylation signals exist. [provided by RefSeq, Jul 2008].

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Featured HSD17B6 Categories

HSD17B6 Antibodies

High quality antibodies with extensive validation data.

HSD17B6 ELISA Kits

Reliable ELISA kits for a wide range of species.

HSD17B6 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended HSD17B6 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Application IHC, WB
Validations
  • (2)
  • (2)
Cat. No. ABIN2776865
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, WB
Validations
  • (2)
Cat. No. ABIN7129746
Quantity 100 μL
Datasheet Datasheet
Reactivity Dog, Human, Mouse
Application IHC, WB
Validations
  • (2)
Cat. No. ABIN629831
Quantity 100 μg
Datasheet Datasheet

Recommended HSD17B6 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Chicken
Analytical Method
Validations
Cat. No. ABIN1772453
Quantity 96 tests
Datasheet Datasheet
Reactivity Guinea Pig
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1747655
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1743994
Quantity 96 tests
Datasheet Datasheet

Recommended HSD17B6 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3081196
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3119848
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN5648435
Quantity 2 μg
Datasheet Datasheet

Latest Publications for our HSD17B6 products

Hooks, Audoux, Fazli, Lesjean, Ernault, Senant, Leste-Lasserre, Hagedorn, Rousseau, Danet, Branchereau, Brugières, Taque, Guettier, Fabre, Rullier, Buendia, Commes, Grosset, Raymond: "New insights into diagnosis and therapeutic options for proliferative hepatoblastoma." in: Hepatology (Baltimore, Md.), (2017) (PubMed).

Mohler, Titus, Bai, Kennerley, Lih, Tomer, Wilson: "Activation of the androgen receptor by intratumoral bioconversion of androstanediol to dihydrotestosterone in prostate cancer." in: Cancer research, Vol. 71, Issue 4, pp. 1486-96, (2011) (PubMed).

Muthusamy, Andersson, Kim, Butler, Waage, Bergerheim, Gustafsson: "Estrogen receptor ? and 17?-hydroxysteroid dehydrogenase type 6, a growth regulatory pathway that is lost in prostate cancer." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 50, pp. 20090-4, (2011) (PubMed).

Huang, Luu-The: "Gene structure, chromosomal localization and analysis of 3-ketosteroid reductase activity of the human 3(alpha-->beta)-hydroxysteroid epimerase." in: Biochimica et biophysica acta, Vol. 1520, Issue 2, pp. 124-30, (2001) (PubMed).

Synonyms and alternative names related to HSD17B6

hydroxysteroid 17-beta dehydrogenase 6 (HSD17B6), hydroxysteroid (17-beta) dehydrogenase 6 (Hsd17b6), hydroxysteroid (17-beta) dehydrogenase 6 (HSD17B6), 17betaHSD9, Hsd17b9, HSE, Rdh8, RODH, SDR9C6

Protein level used designations for HSD17B6

  • 17-beta-HSD 6
  • 17-beta-hydroxysteroid dehydrogenase type 6
  • 3(alpha->beta)-hydroxysteroid epimerase
  • 3(alpha->beta)-hydroxysteroid epimerasel
  • 3-alpha->beta-HSE
  • 3-alpha->beta-hydroxysteroid epimerase
  • 3-hydroxysteroid epimerase
  • NAD+ -dependent 3 alpha-hydroxysteroid dehydrogenase 3-hydroxysteroid epimerase
  • hydroxysteroid (17-beta) dehydrogenase 6 homolog
  • oxidative 3-alpha hydroxysteroid dehydrogenase
  • oxidative 3-alpha-hydroxysteroid-dehydrogenase
  • oxidoreductase
  • retinol dehydrogenase
  • short chain dehydrogenase/reductase family 9C, member 6
  • 17-beta-HSD6
  • 17-beta-HSD9
  • hydroxysteroid (17-beta) dehydrogenase 9
  • hydroxysteroid 17-beta dehydrogenase 9
  • oxidative 17 beta hydroxysteroid dehydrogenase type 6
  • hydroxysteroid 17-beta dehydrogenase 6
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