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Submit your validation data for this product and get a full refund. I want to validate this productRelevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Supplier | Clonality | References | Details |
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1 | ABIN1827663 | IF RNAi ELISA WB | Mouse | IgG2b, kappa | AA 204-303 | Log in to see | 4B5 | 0 |
General |
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Antigen | V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL) Antibodies |
Epitope | AA 204-303, partial Alternatives |
Reactivity | Human Alternatives |
Host | Mouse Alternatives |
Clonality (Clone) | |
Conjugate | This CrkL antibody is un-conjugated Alternatives |
Application |
Immunofluorescence (IF), Proximity Ligation Assay (PLA), RNA Interference (RNAi), ELISA, Western Blotting (WB)
Alternatives
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2 references available |
Supplier | Log in to see |
Product Details anti-CrkL AntibodyTarget Details CrkL Application Details Handling References for anti-CrkL antibody (ABIN514606) Images |
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Cross-Reactivity | Human |
Immunogen |
CRKL (NP_005198, 204 a.a. ~ 303 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Immunogen sequence: AHAYAQPQTT TPLPAVSGSP GAAITPLPST QNGPVFAKAI QKRVPCAYDK TALALEVGDI VKVTRMNING QWEGEVNGRK GLFPFTHVKI FDPQNPDENE |
Clone | 4B5 |
Isotype | IgG2b kappa |
Target Details CrkLProduct Details anti-CrkL Antibody Application Details Handling References for anti-CrkL antibody (ABIN514606) Images back to top |
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Antigen | |
Alternative Name | CRKL (CRKL Antibody Abstract) |
Background |
Full Gene Name: v-crk sarcoma virus CT10 oncogene homolog (avian)-like Synonyms: |
Gene ID | 1399 |
NCBI Accession | NP_005198, NM_005207 |
Pathways | Interferon-gamma Pathway, Neurotrophin Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor |
Application DetailsProduct Details anti-CrkL Antibody Target Details CrkL Handling References for anti-CrkL antibody (ABIN514606) Images back to top |
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Application Notes | Optimal working dilution should be determined by the investigator. |
Comment |
Product Quality tested by: Antibody Reactive Against Recombinant Protein. |
Restrictions | For Research Use only |
HandlingProduct Details anti-CrkL Antibody Target Details CrkL Application Details References for anti-CrkL antibody (ABIN514606) Images back to top |
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Buffer | In 1x PBS, pH 7.4 |
Handling Advice | Aliquot to avoid repeated freezing and thawing. |
Storage | -20 °C |
Storage Comment | Store at -20 °C or lower. Aliquot to avoid repeated freezing and thawing. |
References for anti-CrkL antibody (ABIN514606)Product Details anti-CrkL Antibody Target Details CrkL Application Details Handling Images back to top |
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Product cited in: |
Liu, Chen, Chau, Jan, Chen, Hsu, Lin, Juang, Lu, Cheng, Chen, Chang, Ting, Kao, Hsiao, Huang: "Analysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinoma." in: Molecular & cellular proteomics : MCP, Vol. 12, Issue 5, pp. 1335-49, 2013 Segovis, Schoon, Dick, Nacusi, Leibson, Billadeau: "PI3K links NKG2D signaling to a CrkL pathway involved in natural killer cell adhesion, polarity, and granule secretion." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 11, pp. 6933-42, 2009 |
ImagesProduct Details anti-CrkL Antibody Target Details CrkL Application Details Handling References for anti-CrkL antibody (ABIN514606) back to top |
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Supplier Images |
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