anti-Human CrkL antibody for RNA Interference

Recommended CrkL Antibody (supplied by: Log in to see )

Antigen
V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL) Antibodies
  • CRKL
  • wu:fa55g05
  • wu:fj60e01
  • zgc:63469
  • 1110025F07Rik
  • AA589403
  • AI325100
  • Crkol
  • CRK like proto-oncogene, adaptor protein
  • v-crk avian sarcoma virus CT10 oncogene homolog-like
  • CRKL
  • crkl
  • Crkl
Epitope
AA 204-303, partial
30
29
17
16
15
14
14
11
10
7
6
4
3
3
3
3
3
2
1
1
1
1
1
1
Reactivity
Human
178
96
69
4
2
2
1
Host
Mouse
134
42
23
1
Clonality
Monoclonal
Conjugate
This CrkL antibody is un-conjugated
10
9
9
7
6
5
4
4
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (IF), Proximity Ligation Assay (PLA), RNA Interference (RNAi), ELISA, Western Blotting (WB)
160
82
41
25
24
21
17
7
7
5
4
3
2
1
1
Supplier
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Pubmed
2 references available

Available images

ELISA image for anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL) (AA 204-303), (partial) antibody (ABIN514606)
Western Blotting (WB) image for anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL) (AA 204-303), (partial) antibody (ABIN514606)
Western Blotting (WB) image for anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL) (AA 204-303), (partial) antibody (ABIN514606)
Proximity Ligation Assay (PLA) image for anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL) (AA 204-303), (partial) antibody (ABIN514606)
Proximity Ligation Assay (PLA) image for anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL) (AA 204-303), (partial) antibody (ABIN514606)
Proximity Ligation Assay (PLA) image for anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL) (AA 204-303), (partial) antibody (ABIN514606)
Catalog No. ABIN514606
$ 440.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN1827663 IF RNAi ELISA WB Mouse IgG2b, kappa AA 204-303 Log in to see 4B5 0

General

Antigen V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL) Antibodies
Epitope AA 204-303, partial
(30), (29), (17), (16), (15), (14), (14), (11), (10), (7), (6), (4), (3), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1)
Reactivity Human
(178), (96), (69), (4), (2), (2), (1)
Host Mouse
(134), (42), (23), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CrkL antibody is un-conjugated
(10), (9), (9), (7), (6), (5), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (IF), Proximity Ligation Assay (PLA), RNA Interference (RNAi), ELISA, Western Blotting (WB)
(160), (82), (41), (25), (24), (21), (17), (7), (7), (5), (4), (3), (2), (1), (1)
Pubmed 2 references available
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Product Details anti-CrkL Antibody

Target Details CrkL Application Details Handling References for anti-CrkL antibody (ABIN514606) Images
Cross-Reactivity Human
Immunogen CRKL (NP_005198, 204 a.a. ~ 303 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunogen sequence: AHAYAQPQTT TPLPAVSGSP GAAITPLPST QNGPVFAKAI QKRVPCAYDK TALALEVGDI VKVTRMNING QWEGEVNGRK GLFPFTHVKI FDPQNPDENE
Clone 4B5
Isotype IgG2b kappa
Plasmids, Primers & others

Target Details CrkL

Product Details anti-CrkL Antibody Application Details Handling References for anti-CrkL antibody (ABIN514606) Images back to top
Antigen
Alternative Name CRKL (CRKL Antibody Abstract)
Background Full Gene Name: v-crk sarcoma virus CT10 oncogene homolog (avian)-like
Synonyms:
Gene ID 1399
NCBI Accession NP_005198, NM_005207
Pathways Interferon-gamma Pathway, Neurotrophin Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor

Application Details

Product Details anti-CrkL Antibody Target Details CrkL Handling References for anti-CrkL antibody (ABIN514606) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Comment

Product Quality tested by: Antibody Reactive Against Recombinant Protein.
Restrictions For Research Use only

Handling

Product Details anti-CrkL Antibody Target Details CrkL Application Details References for anti-CrkL antibody (ABIN514606) Images back to top
Buffer In 1x PBS, pH 7.4
Handling Advice Aliquot to avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store at -20 °C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-CrkL antibody (ABIN514606)

Product Details anti-CrkL Antibody Target Details CrkL Application Details Handling Images back to top
Product cited in:

Liu, Chen, Chau, Jan, Chen, Hsu, Lin, Juang, Lu, Cheng, Chen, Chang, Ting, Kao, Hsiao, Huang: "Analysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinoma." in: Molecular & cellular proteomics : MCP, Vol. 12, Issue 5, pp. 1335-49, 2013

Segovis, Schoon, Dick, Nacusi, Leibson, Billadeau: "PI3K links NKG2D signaling to a CrkL pathway involved in natural killer cell adhesion, polarity, and granule secretion." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 11, pp. 6933-42, 2009

Images

Product Details anti-CrkL Antibody Target Details CrkL Application Details Handling References for anti-CrkL antibody (ABIN514606) back to top
Supplier Images
ELISA image for anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL) (AA 204-303), (partial) antibody (ABIN514606) Detection limit for recombinant GST tagged CRKL is approximately 0.3ng/ml as a captur...
Western Blotting (WB) image for anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL) (AA 204-303), (partial) antibody (ABIN514606) Western blot analysis of CRKL over-expressed 293 cell line, cotransfected with CRKL V...
Western Blotting (WB) image for anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL) (AA 204-303), (partial) antibody (ABIN514606) Western Blot analysis of CRKL expression in transfected 293T cell line by CRKL monocl...
Proximity Ligation Assay (PLA) image for anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL) (AA 204-303), (partial) antibody (ABIN514606) Proximity Ligation Analysis of protein-protein interactions between PTK2 and CRKL. Hu...
Proximity Ligation Assay (PLA) image for anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL) (AA 204-303), (partial) antibody (ABIN514606) Proximity Ligation Analysis of protein-protein interactions between GAB1 and CRKL. He...
Proximity Ligation Assay (PLA) image for anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL) (AA 204-303), (partial) antibody (ABIN514606) Proximity Ligation Analysis of protein-protein interactions between HCK and CRKL. Mah...
Immunofluorescence (IF) image for anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL) (AA 204-303), (partial) antibody (ABIN514606) Immunofluorescence of monoclonal antibody to CRKL on HeLa cell. [antibody concentrati...
image for anti-V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL) (AA 204-303), (partial) antibody (ABIN514606) Western Blot detection against Immunogen (36.74 KDa) .