Browse our anti-EPOR (EPOR) Antibodies

Full name:: anti-Erythropoietin Receptor Antibodies (EPOR)

On www.antibodies-online.com are 235 Erythropoietin Receptor (EPOR) Antibodies from 27 different suppliers available. Additionally we are shipping EPOR Kits (64) and EPOR Proteins (30) and many more products for this protein. A total of 341 EPOR products are currently listed.

Synonyms:: EPO-R, epor

list all antibodies	Gene Name	GeneID	UniProt
	EPOR	2057	P19235
	EPOR	13857	P14753
	EPOR	24336
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Most Popular Reactivities for anti-EPOR (EPOR) Antibodies

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anti-Human EPOR Antibodies:

anti-Mouse (Murine) EPOR Antibodies:

anti-Rat (Rattus) EPOR Antibodies:

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Relevant Pathways for anti-EPOR Antibodies

JAK-STAT Signaling

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Top referenced anti-EPOR Antibodies

Human Monoclonal EPOR Primary Antibody for cELISA, FACS - ABIN1720915 : Winkelmann: The human erythropoietin receptor. in International journal of cell cloning 1993 (PubMed)
Show all 5 Pubmed References
Human Polyclonal EPOR Primary Antibody for IF (p), IHC (p) - ABIN686347 : Li, Chen, Shao, Tang, Chen, Chen, Xu: Oxidative stress induces the decline of brain EPO expression in aging rats. in Experimental gerontology 2016 (PubMed)
Show all 2 Pubmed References
Human Polyclonal EPOR Primary Antibody for ICC, IF - ABIN266926 : Fairchild Benyo, Conrad: Expression of the erythropoietin receptor by trophoblast cellsin the human placenta. in Biology of reproduction 1999 (PubMed)
Show all 2 Pubmed References
Human Monoclonal EPOR Primary Antibody for FACS - ABIN4896971 : Pontikoglou, Liapakis, Pyrovolaki, Papadakis, Bux, Eliopoulos, Papadaki: Evidence for downregulation of erythropoietin receptor in bone marrow erythroid cells of patients with chronic idiopathic neutropenia. in Experimental hematology 2006 (PubMed)
Show all 2 Pubmed References
Human Monoclonal EPOR Primary Antibody for FACS - ABIN4896970 : Farha, Asosingh, Xu, Sharp, George, Comhair, Park, Tang, Loyd, Theil, Tubbs, Hsi, Lichtin, Erzurum: Hypoxia-inducible factors in human pulmonary arterial hypertension: a link to the intrinsic myeloid abnormalities. in Blood 2011 (PubMed)
Show all 2 Pubmed References
Human Polyclonal EPOR Primary Antibody for ELISA, ICC - ABIN6261577 : Chen, Li, Quan, Zhou, Zhao, Zhang, Hu, Hu: The Effects of Curcumae Longae Radix, Curcuma phaeocaulis Radix and Their Processed Products on Epo/EpoR Pathway and CD62p. in Frontiers in pharmacology 2018 (PubMed)

More Antibodies against EPOR Interaction Partners

Human Erythropoietin Receptor (EPOR) interaction partners

EpoR role in the proliferation and survival of non-small cell lung cancer cells
Study reports for the first evidence that EPOR modulates breast cancer cell morphology changes upon tamoxifen treatment, which result in increased formation of cell protrusions and subsequent cell death and, proposes sustained AKT (show AKT1 Antibodies) phosphorylation in EPOR-overexpressing cells as a mechanism that can lead to EPOR-induced tamoxifen resistance.
Authors retrospectively investigated whether TFR2 (show TFR2 Antibodies) isoforms and EPOR are differentially expressed in MDS (show PAFAH1B1 Antibodies) patients and whether the expression is associated with patients' clinical outcomes.
High EPOR expression is associated with monoclonal gammopathy of undetermined significance and multiple myeloma.
EPO (show EPO Antibodies)-mediated EPOR signaling reduced the viability of myeloma cell lines and of malignant primary plasma cells in vitro
this study shows that EPO (show EPO Antibodies) could directly promote tumor progression via EPO (show EPO Antibodies) receptor-expressing macrophages
No evidence of in vivo activation of the Epo-R in WAT could be documented despite detectable levels of Epo-R mRNA. CONCLUSION: Thus, in contradiction to animal studies, Epo (show EPO Antibodies) treatment within a physiological relevant range in humans does not exert direct effects in a subcutaneous WAT.
Our results suggest that EPO (show EPO Antibodies)/EPOR pathway promotes gastric cancer formation, proliferation, migration, and decreases apoptosis
These results suggest that both EpoR-positive and EpoR-negative cancer cells could be regulated by exogenous Epo (show EPO Antibodies). However, an increased response to erythropoietin (show EPO Antibodies) was observed in the EpoR-positive cells. Thus, erythropoietin (show EPO Antibodies) increases the risk of tumor progression in colon cancer and should not be used to treat anemia in this type of cancer.
Overexpression of EPOR is associated with clear cell renal cell carcinoma (show MOK Antibodies).

Mouse (Murine) Erythropoietin Receptor (EPOR) interaction partners

CIS (show CISH Antibodies) interacted with phosphorylated EpoR at Y401, which was critical for the activation of STAT5 (show STAT5A Antibodies) and ERK (show EPHB2 Antibodies).
these results have revealed that phosphorylation of Tyr (show TYR Antibodies)-343, Tyr (show TYR Antibodies)-460, and Tyr (show TYR Antibodies)-464 in EpoR underlies JAK2 (show JAK2 Antibodies) V617F mutant-induced tumorigenesis.
A solution NMR study of the mouse erythropoietin receptor (mEpoR) comprising the transmembrane domain and the juxtamembrane regions reconstituted in dodecylphosphocholine (DPC) micelles.
These data indicate that EpoR signaling is associated with cardiac remodeling following chronic iron deficiency.
We propose that the CID (show CENPA Antibodies)-dependent dimerization system combined with the EpoR intracellular domain and the Gata1 (show GATA1 Antibodies) gene regulatory region generates a novel peroral strategy for the treatment of anemia.
transmembrane domain and the juxtamembrane region of the erythropoietin receptor in micelles
EpoR and its activity are downstream effectors of Klotho (show KL Antibodies) enabling it to function as a cytoprotective protein against oxidative injury.
Expression of EPOR in rod photoreceptors, Muller cells, and amacrine, horizontal, and ganglion cells of the peripheral retina is not required for the maturation, function, and survival of these cells in aging tissue.
Data indicate a Cbl (show CBL Antibodies)/p85 (show ECM1 Antibodies)/epsin-1 (show EPN1 Antibodies) pathway in erythropoietin receptor (EpoR) endocytosis.
Data from knockout mice suggest that adipose tissue-specific disruption of EPO (show EPO Antibodies) receptor does not alter adipose tissue expansion, adipocyte morphology, insulin (show INS Antibodies) resistance, inflammation, or angiogenesis.

EPOR Antigen Profile

Antigen Summary

This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.

Alternative names and synonyms associated with EPOR

erythropoietin receptor (EPOR) antibody
erythropoietin receptor (epor) antibody
erythropoietin receptor (Epor) antibody
erythropoietin receptor L homeolog (epor.L) antibody

EPO-R antibody
epor antibody

Protein level used designations for EPOR

erythropoietin receptor , Erythropoietin receptor , type I single-transmembrane cytokine receptor , erythropoietin receptor-like , EPO-R , xlEPOR

GENE ID	SPECIES
714546	Macaca mulatta
100195206	Salmo salar
455728	Pan troglodytes
751109	Danio rerio
100389634	Callithrix jacchus
100452294	Pongo abelii
2057	Homo sapiens
13857	Mus musculus
24336	Rattus norvegicus
484943	Canis lupus familiaris
397554	Sus scrofa
281144	Bos taurus
100721190	Cavia porcellus
443227	Ovis aries
734211	Xenopus laevis
100355350	Oryctolagus cuniculus

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Show all anti-Erythropoietin Receptor (EPOR) Antibodies with Pubmed References

Human Erythropoietin Receptor (EPOR) interaction partners

Mouse (Murine) Erythropoietin Receptor (EPOR) interaction partners

Antigen Summary

Alternative names and synonyms associated with EPOR

Protein level used designations for EPOR