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|Antigen||Interleukin 13 Receptor, alpha 1 (IL13RA1) Antibodies|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This IL13 Receptor alpha 1 antibody is un-conjugated Alternatives|
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Product Details anti-IL13 Receptor alpha 1 AntibodyTarget Details IL13 Receptor alpha 1 Application Details Handling Images
|Specificity||This antibody detects endogenous levels of IL-13R-alpha-1 protein. (region surrounding Lys401)|
Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
|Purification||Affinity Chromatography using epitope-specific immunogen|
Target Details IL13 Receptor alpha 1Product Details anti-IL13 Receptor alpha 1 Antibody Application Details Handling Images back to top
|Alternative Name||CD213a1 / IL13RA1 (IL13RA1 Antibody Abstract)|
|Background||The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.Synonyms: CT19, Cancer/testis antigen 19, IL-13R-alpha-1, IL-13RA-1, IL13 receptor alpha, IL13R, IL13RA, Interleukin-13 receptor alpha-1 chain|
|Molecular Weight||approx. 49 kDa|
|Pathways||JAK-STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response|
Application DetailsProduct Details anti-IL13 Receptor alpha 1 Antibody Target Details IL13 Receptor alpha 1 Handling Images back to top
Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-IL13 Receptor alpha 1 Antibody Target Details IL13 Receptor alpha 1 Application Details Images back to top
|Buffer||Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.|
ImagesProduct Details anti-IL13 Receptor alpha 1 Antibody Target Details IL13 Receptor alpha 1 Application Details Handling back to top