|Antigen||Interleukin 2 (IL2) Antibodies|
|Reactivity||Human, Monkey Alternatives|
|Conjugate||This IL2 antibody is un-conjugated Alternatives|
Functional Studies (Func), Enzyme Immunoassay (EIA), Western Blotting (WB)
|Supplier||Log in to see|
Product Details anti-IL2 AntibodyTarget Details IL2 Application Details Handling Images
|Immunogen||Recombinant human IL-2|
Target Details IL2Product Details anti-IL2 Antibody Application Details Handling Images back to top
|Alternative Name||Interleukin-2 / IL2 (IL2 Antibody Abstract)|
|Background||Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies. This is probably mediated by cytotoxic effector cells.Synonyms: IL-2, T-cell growth factor, TCGF|
|Pathways||JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation|
Application DetailsProduct Details anti-IL2 Antibody Target Details IL2 Handling Images back to top
ELISA: 5g/mL - 10g/mL. Western Blot. Functional Assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-IL2 Antibody Target Details IL2 Application Details Images back to top
|Buffer||Phosphate buffered saline|
|Handling Advice||Avoid repeated freezing and thawing.|