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|Antigen||Interleukin 21 Receptor (IL21R) Antibodies|
|Conjugate||This IL21 Receptor antibody is un-conjugated Alternatives|
ELISA, Fluorescence Microscopy (FM), Immunohistochemistry (IHC), Western Blotting (WB)
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Product Details anti-IL21 Receptor AntibodyTarget Details IL21 Receptor Application Details Handling Images
|Cross-Reactivity||Human, Mouse (Murine), Rat (Rattus)|
|Cross-Reactivity (Details)||Cross reactivity with IL-21 Receptor from other sources has not been determined.|
|Purification||Anti-IL-21 Receptor Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography.|
Immunogen: Anti-IL-21 receptor antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 97 to 111 of human IL-21 receptor precursor.
Immunogen Type: Peptide
|Plasmids, Primers & others|
Target Details IL21 ReceptorProduct Details anti-IL21 Receptor Antibody Application Details Handling Images back to top
|Alternative Name||IL-21 Receptor (IL21R Antibody Abstract)|
Synonyms: IL-21 Receptor Antibody, NILR, CD360, NILR, UNQ3121/PRO10273, Interleukin-21 receptor, Novel interleukin receptor, IL-21 receptor
Background: A novel cytokine related to IL-2 and IL-15 was recently identified and designated IL-21. The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family. IL-21R forms a complex with the common cytokine receptor gamma chain, gammac, and mediates IL-21 signaling. Both IL-21R and the gammac are necessary for the IL-21 function. IL-21 and its receptor activate JAK-STAT signaling pathway. IL-21R is expressed in spleen, thymus, natural killer (NK), T and B cell lines. IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations.
Gene Name: IL21R
Application DetailsProduct Details anti-IL21 Receptor Antibody Target Details IL21 Receptor Handling Images back to top
Immunohistochemistry Dilution: 10 μg/mL
Application Note: Anti-IL-21 Receptor Antibody has been tested for use in ELISA, Western Blotting, Immunohistochemistry and Immunofluorescence. Specific conditions for reactivity should be optimized by the end user. Expect a band at approximately 59 kDa in Western Blots of specific cell lysates and tissues.
ELISA Dilution: 1:10,000
Western Blot Dilution: 1 μg/mL
IF Microscopy Dilution: 20 μg/mL
|Restrictions||For Research Use only|
HandlingProduct Details anti-IL21 Receptor Antibody Target Details IL21 Receptor Application Details Images back to top
Buffer: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage||RT,4 °C,-20 °C|
|Storage Comment||Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.|
ImagesProduct Details anti-IL21 Receptor Antibody Target Details IL21 Receptor Application Details Handling back to top