anti-Human IL7R antibody for Cytometry by Time of Flight

Recommended IL7R Antibody (supplied by: Log in to see )

Antigen
Interleukin 7 Receptor (IL7R) Antibodies
  • IL7R
  • CD127
  • IL-7Ralpha
  • CDW127
  • IL-7R-alpha
  • IL7RA
  • ILRA
  • IL-7RA
  • interleukin 7 receptor
  • IL7R
  • Il7r
Reactivity
Human
237
207
48
5
2
2
1
Host
Goat
144
138
92
16
7
4
1
Clonality
Polyclonal
Conjugate
This IL7R antibody is un-conjugated
30
28
24
19
16
14
12
8
7
7
7
6
6
5
5
5
4
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
Application
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Western Blotting (WB)
179
175
82
73
45
26
20
12
12
10
9
8
5
4
3
3
2
2
2
1
1
1
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Catalog No. ABIN4900788
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN4900541 CyTOF FACS WB Mouse IgG1 Extracellular Domain Log in to see 40131 5
1 ABIN2659645 BR CyTOF FACS IHC IP St PE/Dazzle™ 594 Mouse IgG1 kappa Log in to see A019D5 6
1 ABIN4325442 CyTOF FACS IHC IHC (p) WB Mouse IgG2b lambda Log in to see 22F3D9 0
1 ABIN2659646 BR CyTOF FACS IHC IP St PE/Dazzle™ 594 Mouse IgG1 kappa Log in to see A019D5 6
1 ABIN4325441 CyTOF FACS IHC IHC (p) WB Mouse IgG2b lambda Log in to see 22F3D9 0

General

Antigen Interleukin 7 Receptor (IL7R) Antibodies
Reactivity Human
(237), (207), (48), (5), (2), (2), (1)
Host Goat
(144), (138), (92), (16), (7), (4), (1)
Clonality
Polyclonal
Conjugate This IL7R antibody is un-conjugated
(30), (28), (24), (19), (16), (14), (12), (8), (7), (7), (7), (6), (6), (5), (5), (5), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Application Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Western Blotting (WB)
(179), (175), (82), (73), (45), (26), (20), (12), (12), (10), (9), (8), (5), (4), (3), (3), (2), (2), (2), (1), (1), (1)
Pubmed 6 references available
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Product Details anti-IL7R Antibody

Target Details IL7R Application Details Handling References for anti-IL7R antibody (ABIN4900788) Images
Specificity Detects human IL-7 R alpha in direct ELISAs and Western blots. In direct ELISAs, less than 15 % cross-reactivity with recombinant rat IL-7 R alpha and less than 5 % cross-reactivity with recombinant mouse IL-7 R alpha is observed.
Purification Antigen Affinity-purified
Sterility 0.2 μm filtered
Immunogen Mouse myeloma cell line NS0-derived recombinant human IL-7 R alpha/CD127
Isotype IgG
Plasmids, Primers & others

Target Details IL7R

Product Details anti-IL7R Antibody Application Details Handling References for anti-IL7R antibody (ABIN4900788) Images back to top
Antigen
Alternative Name IL-7 R alpha/cd127 (IL7R Antibody Abstract)
Background Alternative Names: CD127, CD127 antigen, CD127ILRA, CDW127, IL-7 receptor subunit alpha, IL7R, IL7R alpha, IL-7R subunit alpha, IL7RA, IL-7RA, IL-7R-alpha, interleukin 7 receptor, interleukin 7 receptor alpha chain, interleukin 7 receptor isoform H5-6, interleukin-7 receptor subunit alpha
Gene ID 3575
Pathways JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size

Application Details

Product Details anti-IL7R Antibody Target Details IL7R Handling References for anti-IL7R antibody (ABIN4900788) Images back to top
Application Notes Western Blot 0.1 μg/mL
Flow Cytometry 0.25 μg/10^6 cells
CyTOF-ready
Restrictions For Research Use only

Handling

Product Details anti-IL7R Antibody Target Details IL7R Application Details References for anti-IL7R antibody (ABIN4900788) Images back to top
Reconstitution Reconstitute at 0.2 mg/mL in sterile PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative Without preservative
Storage 4 °C,-20 °C,-80 °C
Storage Comment Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Expiry Date 12 months

References for anti-IL7R antibody (ABIN4900788)

Product Details anti-IL7R Antibody Target Details IL7R Application Details Handling Images back to top
Product cited in:

Steele, Carrasco-Medina, Sodora, Crawley: "Increased soluble IL-7 receptor concentrations associate with improved IL-7 therapy outcomes in SIV-infected ART-treated Rhesus macaques." in: PLoS ONE, Vol. 12, Issue 12, pp. e0188427, 2018 Method employed by authors: Luminex Assay (LMNX) (Sample species: Rhesus Monkey).

Lundtoft, Afum-Adjei Awuah, Rimpler, Harling, Nausch, Kohns, Adankwah, Lang, Olbrich, Mayatepek, Owusu-Dabo, Jacobsen: "Aberrant plasma IL-7 and soluble IL-7 receptor levels indicate impaired T-cell response to IL-7 in human tuberculosis." in: PLoS pathogens, Vol. 13, Issue 6, pp. e1006425, 2017 Method employed by authors: Flow Cytometry (FACS), Flow Cytometry (FACS) (Sample species: Human).

Shin, You, Kang, Lee, Yoo, Park, Kang, Kim, Mohanty, Shaw, Montgomery, Hwang, Kang: "DNA Methylation Regulates the Differential Expression of CX3CR1 on Human IL-7Rαlow and IL-7Rαhigh Effector Memory CD8+ T Cells with Distinct Migratory Capacities to the Fractalkine." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 6, pp. 2861-9, 2015 Method employed by authors: Flow Cytometry (FACS), Flow Cytometry (FACS), Flow Cytometry (FACS) (Sample species: Human).

Takao, Asanoma, Kato, Fukushima, Tsunematsu, Hirakawa, Matsumura, Seki, Takeda, Wake: "Isolation and characterization of human trophoblast side-population (SP) cells in primary villous cytotrophoblasts and HTR-8/SVneo cell line." in: PLoS ONE, Vol. 6, Issue 7, pp. e21990, 2011 Method employed by authors: Magnetic Beads (MB), Magnetic Beads (MB), Magnetic Beads (MB) (Sample species: Human).

Mengshol, Golden-Mason, Arikawa, Smith, Niki, McWilliams, Randall, McMahan, Zimmerman, Rangachari, Dobrinskikh, Busson, Polyak, Hirashima, Rosen: "A crucial role for Kupffer cell-derived galectin-9 in regulation of T cell immunity in hepatitis C infection." in: PLoS ONE, Vol. 5, Issue 3, pp. e9504, 2010 Method employed by authors: Flow Cytometry (FACS), Flow Cytometry (FACS), Flow Cytometry (FACS) (Sample species: Human).

Faller, Sugden, McVey, Kakal, MacPherson: "Soluble HIV Tat protein removes the IL-7 receptor alpha-chain from the surface of resting CD8 T cells and targets it for degradation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 5, pp. 2854-66, 2010 Method employed by authors: Immunoprecipitation (IP), Immunoprecipitation (IP), Immunoprecipitation (IP) (Sample species: Human).