anti-Human IL7R antibody for Cytometry by Time of Flight

Recommended IL7R Antibody (supplied by: Log in to see )

Antigen
Interleukin 7 Receptor (IL7R) Antibodies
  • IL7R
  • CD127
  • IL-7Ralpha
  • CDW127
  • IL-7R-alpha
  • IL7RA
  • ILRA
  • IL-7RA
  • interleukin 7 receptor
  • IL7R
  • Il7r
Epitope
Extracellular Domain
29
28
18
15
15
13
10
8
7
7
6
6
5
5
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Human
267
238
48
6
2
2
1
Host
Mouse
163
149
117
18
7
4
1
Clonality
Monoclonal
Conjugate
This IL7R antibody is un-conjugated
32
30
28
23
18
17
13
12
9
9
9
7
6
6
6
6
5
5
5
5
5
5
5
4
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
Application
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Western Blotting (WB)
221
203
86
78
49
26
20
13
12
12
9
8
5
4
3
3
2
2
2
1
1
1
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Catalog No. ABIN4900541
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN4900788 CyTOF FACS WB Goat IgG Log in to see Polyclonal 5
1 ABIN2659645 BR CyTOF FACS IHC IP St PE/Dazzle™ 594 Mouse IgG1 kappa Log in to see A019D5 6
1 ABIN4325442 CyTOF FACS IHC IHC (p) WB Mouse IgG2b lambda Log in to see 22F3D9 0
1 ABIN2659646 BR CyTOF FACS IHC IP St PE/Dazzle™ 594 Mouse IgG1 kappa Log in to see A019D5 6
1 ABIN4325441 CyTOF FACS IHC IHC (p) WB Mouse IgG2b lambda Log in to see 22F3D9 0
1 ABIN4226078 CyTOF FACS WB Mouse IgG1 Log in to see MM0411-10V5 0

General

Antigen Interleukin 7 Receptor (IL7R) Antibodies
Epitope Extracellular Domain
(29), (28), (18), (15), (15), (13), (10), (8), (7), (7), (6), (6), (5), (5), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(267), (238), (48), (6), (2), (2), (1)
Host Mouse
(163), (149), (117), (18), (7), (4), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IL7R antibody is un-conjugated
(32), (30), (28), (23), (18), (17), (13), (12), (9), (9), (9), (7), (6), (6), (6), (6), (5), (5), (5), (5), (5), (5), (5), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Application Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Western Blotting (WB)
(221), (203), (86), (78), (49), (26), (20), (13), (12), (12), (9), (8), (5), (4), (3), (3), (2), (2), (2), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-IL7R Antibody

Target Details IL7R Application Details Handling References for anti-IL7R antibody (ABIN4900541) Images
Specificity Detects human IL-7 R alpha in Western blots. In Western blots, approximately 5 % cross-reactivity was observed with recombinant human (rh) IL-10 R, rhIL-2 R beta , rhIL-5 R alpha , and rhIL-6 R.
Purification Protein A or G purified from ascites
Sterility 0.2 μm filtered
Immunogen Mouse myeloma cell line NS0-derived recombinant human IL-7 R alpha , Extracellular domain
Clone 40131
Isotype IgG1
Plasmids, Primers & others

Target Details IL7R

Product Details anti-IL7R Antibody Application Details Handling References for anti-IL7R antibody (ABIN4900541) Images back to top
Antigen
Alternative Name IL-7 R alpha/cd127 (IL7R Antibody Abstract)
Background Alternative Names: CD127, CD127 antigen, CD127ILRA, CDW127, IL-7 receptor subunit alpha, IL7R, IL7R alpha, IL-7R subunit alpha, IL7RA, IL-7RA, IL-7R-alpha, interleukin 7 receptor, interleukin 7 receptor alpha chain, interleukin 7 receptor isoform H5-6, interleukin-7 receptor subunit alpha
Gene ID 3575
Pathways JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size

Application Details

Product Details anti-IL7R Antibody Target Details IL7R Handling References for anti-IL7R antibody (ABIN4900541) Images back to top
Application Notes Western Blot 1 μg/mL
Flow Cytometry 2.5 μg/10^6 cells
CyTOF-ready
Restrictions For Research Use only

Handling

Product Details anti-IL7R Antibody Target Details IL7R Application Details References for anti-IL7R antibody (ABIN4900541) Images back to top
Reconstitution Reconstitute at 0.5 mg/mL in sterile PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative Without preservative
Storage 4 °C,-20 °C,-80 °C
Storage Comment Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Expiry Date 12 months

References for anti-IL7R antibody (ABIN4900541)

Product Details anti-IL7R Antibody Target Details IL7R Application Details Handling Images back to top
Product cited in:

Kreft, Verbraak, Wierenga-Wolf, van Meurs, Oostra, Laman, Hintzen: "Decreased systemic IL-7 and soluble IL-7Rα in multiple sclerosis patients." in: Genes and immunity, Vol. 13, Issue 7, pp. 587-92, 2012 Method employed by authors: ELISA (ELISA) (Sample species: Human).

Hoe, McKay, Schibeci, Gandhi, Heard, Stewart, Booth: "Functionally significant differences in expression of disease-associated IL-7 receptor alpha haplotypes in CD4 T cells and dendritic cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 5, pp. 2512-7, 2010 Method employed by authors: ELISA (ELISA) (Sample species: Human).

Rose, Pillet, Lavergne, Tamarit, Lenormand, Rousselle, Namane, Thèze: "Interleukin-7 compartmentalizes its receptor signaling complex to initiate CD4 T lymphocyte response." in: The Journal of biological chemistry, Vol. 285, Issue 20, pp. 14898-908, 2010 Method employed by authors: Immunoprecipitation (IP) (Sample species: Human).

Rose, Lambotte, Pallier, Delfraissy, Colle: "Identification and biochemical characterization of human plasma soluble IL-7R: lower concentrations in HIV-1-infected patients." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 12, pp. 7389-97, 2009 Method employed by authors: ELISA (ELISA) (Sample species: Human).

Srivastava, Srivastava: "Establishment and characterization of SRIK-NKL: a novel CD8+ natural killer/T cell line derived from a patient with leukemic phase of acute lymphoblastic lymphoma." in: Leukemia research, Vol. 29, Issue 7, pp. 771-83, 2005 Method employed by authors: Immunocytochemistry (ICC) (Sample species: Human).

Images

Product Details anti-IL7R Antibody Target Details IL7R Application Details Handling References for anti-IL7R antibody (ABIN4900541) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-Interleukin 7 Receptor (IL7R) (Extracellular Domain) antibody (ABIN4900541) Detection of IL-7 R alpha/CD127 in Human Blood Lymphocytes by Flow Cytometry. Human p...