anti-Mouse (Murine) IL7R antibody for ELISA

Recommended IL7R Antibody

Antigen
Interleukin 7 Receptor (IL7R) Antibodies
  • IL7R
  • CD127
  • IL-7Ralpha
  • CDW127
  • IL-7R-alpha
  • IL7RA
  • ILRA
  • IL-7RA
  • interleukin 7 receptor
  • IL7R
  • Il7r
Epitope
pTyr449
30
16
15
13
11
8
8
7
6
6
5
5
4
3
3
3
3
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Mouse (Murine)
177
173
42
7
5
2
2
1
Host
Rabbit
155
82
30
14
7
2
1
Clonality
Polyclonal
Conjugate
This IL7R antibody is un-conjugated
24
21
16
12
8
8
7
7
4
4
4
4
4
4
4
2
2
2
2
2
2
2
2
2
1
Application
Immunoprecipitation (IP), ELISA, Western Blotting (WB)
121
114
80
32
26
15
12
11
9
7
4
3
1
1
Options

Available images

Catalog No. ABIN233847
$ 598.50
Plus shipping costs $45.00 and $22.60 dry ice
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
19.59232 ABIN3185181 ELISA WB Rabbit IgG Ser552 Polyclonal 0
13.59232 ABIN768570 ELISA WB Goat Internal Region Polyclonal 0
13.59232 ABIN3182449 ELISA IF WB Rabbit IgG pTyr449 Polyclonal 0
10 ABIN6262569 ELISA ICC IF IHC WB Rabbit IgG Polyclonal 0
7 ABIN1531668 IF ELISA WB Rabbit IgG AA 410-459, pTyr449 Polyclonal 0
7 ABIN351552 ELISA IHC IHC (p) WB Rabbit C-Term Polyclonal 0
7 ABIN351553 ELISA IHC IHC (p) WB Rabbit pTyr449 Polyclonal 0
4 ABIN2664193 CyTOF ELISA IF IHC ICFC WB Rat IgG2b kappa SB-199 9
4 ABIN1532692 ELISA WB Rabbit IgG AA 410-459 Polyclonal 1
4 ABIN2464495 ELISA WB Goat Internal Region Polyclonal 0
4 ABIN793354 ELISA WB Goat AA 36-47 Polyclonal 0
4 ABIN5958590 ELISA WB Rabbit IgG Tyr449 Polyclonal 0
4 ABIN1735890 IHC (p) ELISA WB Rabbit IgG pTyr449 Polyclonal 0
4 ABIN2470756 IHC ELISA WB Rabbit pTyr449 Polyclonal 0
4 ABIN2935551 ELISA WB Rabbit IgG Polyclonal 0
4 ABIN1735889 IHC (p) ELISA WB Rabbit IgG C-Term Polyclonal 0
4 ABIN5889186 ELISA Goat Polyclonal 0
4 ABIN5580911 ELISA WB Goat Polyclonal 0
4 ABIN2561663 ELISA WB Goat IgG Internal Region Polyclonal 0
4 ABIN4951456 ELISA WB Goat Ig Fraction Polyclonal 0

General

Antigen Interleukin 7 Receptor (IL7R) Antibodies
Epitope pTyr449
(30), (16), (15), (13), (11), (8), (8), (7), (6), (6), (5), (5), (4), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Mouse (Murine)
(177), (173), (42), (7), (5), (2), (2), (1)
Host Rabbit
(155), (82), (30), (14), (7), (2), (1)
Clonality
Polyclonal
Conjugate This IL7R antibody is un-conjugated
(24), (21), (16), (12), (8), (8), (7), (7), (4), (4), (4), (4), (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application Immunoprecipitation (IP), ELISA, Western Blotting (WB)
(121), (114), (80), (32), (26), (15), (12), (11), (9), (7), (4), (3), (1), (1)
Pubmed 1 reference available
Supplier

Product Details anti-IL7R Antibody

Target Details IL7R Application Details Handling References for anti-IL7R antibody (ABIN233847) Images
Cross-Reactivity Mouse (Murine), Rat (Rattus)
Characteristics Concentration Definition: by UV absorbance at 280 nm
Immunogen This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to residues near Y449 of mouse IL-7 protein.
Isotype IgG
Plasmids, Primers & others

Target Details IL7R

Product Details anti-IL7R Antibody Application Details Handling References for anti-IL7R antibody (ABIN233847) Images back to top
Antigen
Alternative Name IL-7 Receptor Alpha Chain (IL7R Antibody Abstract)
Background This antibody is designed, produced, and is suitable for Cancer, Immunology and Nuclear Signaling research. Interleukin-7 is a glycoprotein involved in the regulation of lymphopoiesis. Response of cells to IL7 is dependent on the presence of the interleukin 7 receptor (IL7R); the active receptor is an alpha/gamma chain heterodimer. The gamma(c) chain, which also associates with the interleukin-2 receptor, serves primarily to activate signal transduction by the IL7R complex, while the alpha chain of IL7R determines specific signaling events through its association with cytoplasmic signaling molecules.  The human and mouse sequence is nearly identical.  In humans, severe combined immunodeficiency is caused by genetic defects in IL-7 receptor. The tyrosine residue at the 449 position is a critical signaling site of the intracellular domain of IL-7 receptor. This site is rapidly phosphorylated by janus kinases after the IL-7 receptor is engaged. IL-7 Receptor Alpha Chain phospho Y449 Antibody is ideal for investigators involved in Cell Signaling, Signal Transduction and Immunology research.
Synonyms: IL7Ralpha antibody, Interleukin 7 receptor alpha chain antibody, Interleukin 7 receptor antibody
Gene ID 16197, 45269152
UniProt P16872
Pathways JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size

Application Details

Product Details anti-IL7R Antibody Target Details IL7R Handling References for anti-IL7R antibody (ABIN233847) Images back to top
Application Notes This affinity purified antibody has been tested for use in ELISA, immunoprecipitation, and western blotting.  Specific conditions for reactivity should be optimized by the end user.  Expect a band approximately 55 kDa in size corresponding to phosphorylated IL-7 by western blotting in the appropriate cell lysate or extract.  This phospho-specific polyclonal antibody reacts with mouse IL-7 pY449 and shows minimal reactivity by ELISA against the non-phosphorylated form of the immunizing peptide.
Restrictions For Research Use only

Handling

Product Details anti-IL7R Antibody Target Details IL7R Application Details References for anti-IL7R antibody (ABIN233847) Images back to top
Format Liquid
Concentration 0.82 mg/mL
Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C

References for anti-IL7R antibody (ABIN233847)

Product Details anti-IL7R Antibody Target Details IL7R Application Details Handling Images back to top
Product cited in:

Osborne, Dhanji, Snow, Priatel, Ma, Miners, Teh, Goldsmith, Abraham: "Impaired CD8 T cell memory and CD4 T cell primary responses in IL-7R alpha mutant mice." in: The Journal of experimental medicine, Vol. 204, Issue 3, pp. 619-31, 2007

Images

Product Details anti-IL7R Antibody Target Details IL7R Application Details Handling References for anti-IL7R antibody (ABIN233847) back to top
Supplier Images
Western Blotting (WB) image for anti-Interleukin 7 Receptor (IL7R) (pTyr449) antibody (ABIN233847) Western Blot and immunoprecipitation of Rabbit anti- IL-7-Receptor-alpha-chain-pY449 ...
 image for anti-Interleukin 7 Receptor (IL7R) (pTyr449) antibody (ABIN233847) anti-Interleukin 7 Receptor (IL7R) (pTyr449) antibody (Image 2)