anti-Mouse (Murine) MPL antibody for Flow Cytometry

Recommended MPL Antibody (supplied by: Log in to see )

Antigen
Myeloproliferative Leukemia Virus Oncogene (MPL) Antibodies
  • C-MPL
  • CD110
  • MPLV
  • THCYT2
  • TPOR
  • TPO-R
  • c-mpl
  • c-mpl-I
  • c-mpl-II
  • hlb219
  • MPL
  • mpll
  • tpor
  • tpor.b
  • MPL proto-oncogene, thrombopoietin receptor
  • myeloproliferative leukemia virus oncogene
  • MPL
  • Mpl
  • mpl
Reactivity
Human, Mouse (Murine), Rat (Rattus)
61
38
31
1
1
Host
Rabbit
50
16
Clonality
Polyclonal
Conjugate
This MPL antibody is un-conjugated
4
4
4
2
2
2
2
2
2
2
2
2
2
2
2
1
Application
Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
34
29
25
14
6
5
4
2
1
Options
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Catalog No. ABIN1387832
$ 306.90
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN1390517 FACS IF (p) Alexa Fluor 555 Rabbit IgG Log in to see Polyclonal 0
1 ABIN1390520 FACS IF (p) FITC Rabbit IgG Log in to see Polyclonal 0
1 ABIN1390516 FACS IF (p) Alexa Fluor 488 Rabbit IgG Log in to see Polyclonal 0
1 ABIN1390515 FACS IF (p) Alexa Fluor 350 Rabbit IgG Log in to see Polyclonal 0
1 ABIN1390518 FACS IF (p) Alexa Fluor 647 Rabbit IgG Log in to see Polyclonal 0
1 ABIN1425855 FACS PE Rabbit IgG Log in to see Polyclonal 0
1 ABIN1408407 FACS IF (p) Cy3 Rabbit IgG Log in to see Polyclonal 0
1 ABIN1408409 FACS IF (p) Cy5.5 Rabbit IgG Log in to see Polyclonal 0
1 ABIN1408410 FACS IF (p) Cy7 Rabbit IgG Log in to see Polyclonal 0
1 ABIN1408408 FACS IF (p) Cy5 Rabbit IgG Log in to see Polyclonal 0
1 ABIN2809014 FACS IF (p) Alexa Fluor 594 Rabbit IgG Log in to see Polyclonal 0
1 ABIN5011834 FACS IF (p) Alexa Fluor 750 Rabbit IgG Log in to see Polyclonal 0
1 ABIN5011833 FACS IF (p) Alexa Fluor 680 Rabbit IgG Log in to see Polyclonal 0

General

Antigen Myeloproliferative Leukemia Virus Oncogene (MPL) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(61), (38), (31), (1), (1)
Host Rabbit
(50), (16)
Clonality
Polyclonal
Conjugate This MPL antibody is un-conjugated
(4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(34), (29), (25), (14), (6), (5), (4), (2), (1)
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Product Details anti-MPL Antibody

Target Details MPL Application Details Handling Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human TPOR
Isotype IgG

Target Details MPL

Product Details anti-MPL Antibody Application Details Handling Images back to top
Antigen
Alternative Name Tpor (MPL Antibody Abstract)
Background

Thrombopoietin (TPO or THPO), also known as c-Mpl ligand (c-Mpl L), is a cytokine that plays a central role in megakaryopoiesis by influencing the development and maturation of megakaryocytes and platelet production from hematopoietic stem cells. TPO exerts its biological effects through the TPO receptor, c-Mpl. c-Mpl is a member of the cytokine receptor superfamily. Expression of c-Mpl is restricted to hematopoietic tissues and cells, such as bone marrow, spleen, fetal liver and CD34+ cells. Stimulation of c-Mpl with TPO results in the activation of the Janus tyrosine kinase family members, Tyk 2 and JAK2, which in turn phosphorylate Stat5 and Stat3, causing their nuclear translocation and the transcription of Stat responsive genes. Muta-tions in c-Mpl have been implicated as the cause of certain human disorders, including congenital amegakaryocytic thrombocytopenia (CAMT) and thrombocytopenia with absent radii (TAR) syndrome.

Subcellular location: Extracellular

Synonyms: C MPL, C-MPL, CMPL, CD110, CD 110, MPL, MPLV, Myeloprolerative leukemia protein, Myeloprolerative leukemia virus oncogene, Proto-oncogene c-Mpl, THCYT2, Thrombopoietin receptor, TPO R, TPO-R, TPOR, TPOR_HUMAN.

Pathways JAK-STAT Signaling

Application Details

Product Details anti-MPL Antibody Target Details MPL Handling Images back to top
Application Notes WB 1:100-1000
FCM 1:20-100
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only

Handling

Product Details anti-MPL Antibody Target Details MPL Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

Images

Product Details anti-MPL Antibody Target Details MPL Application Details Handling back to top
Supplier Images
Flow Cytometry (FACS) image for anti-Myeloproliferative Leukemia Virus Oncogene (MPL) antibody (ABIN1387832) Human Raji cells probed with TPOR Polyclonal Antibody, Unconjugated (green) at 1:100...