anti-Human PTPN6 antibody for Immunohistochemistry (Frozen Sections)

Recommended PTPN6 Antibody (supplied by: Log in to see )

Antigen
Protein-tyrosine Phosphatase 1C (PTPN6) Antibodies
  • HCPH
  • HPTP1C
  • PTP-1C
  • SH-PTP1
  • SHP-1
  • SHP-1L
  • SHP1
  • DRPLA
  • Hcph
  • Ptp1C
  • me
  • motheaten
  • Ptph6
  • Shp-1
  • fj22f05
  • wu:fj22f05
  • zgc:55501
  • ptpn6
  • protein tyrosine phosphatase, non-receptor type 6
  • protein tyrosine phosphatase, non-receptor type 6 L homeolog
  • PTPN6
  • Ptpn6
  • ptpn6
  • ptpn6.L
Reactivity
Human
231
101
92
5
4
2
2
2
1
1
1
1
1
Host
Mouse
157
40
35
Clonality
Monoclonal
Conjugate
This PTPN6 antibody is un-conjugated
9
9
8
3
3
3
3
3
3
3
3
3
3
3
3
3
2
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Western Blotting (WB)
169
104
73
40
39
36
22
11
8
7
7
4
2
1
Supplier
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Catalog No. ABIN452175
$ 544.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN452174 EIA IHC (fro) IF WB Mouse IgG1 Log in to see PTY11 0
1 ABIN114551 EIA IHC (fro) IF WB Mouse IgG2a Log in to see PTY10 0
1 ABIN114552 IHC (fro) IP WB Mouse IgG2a Log in to see PTY13 0
1 ABIN114550 EIA IHC (fro) IF WB Mouse IgG1 Log in to see PTY6 0

General

Antigen Protein-tyrosine Phosphatase 1C (PTPN6) Antibodies
Reactivity Human
(231), (101), (92), (5), (4), (2), (2), (2), (1), (1), (1), (1), (1)
Host Mouse
(157), (40), (35)
Clonality (Clone)
Monoclonal   ( )
Conjugate This PTPN6 antibody is un-conjugated
(9), (9), (8), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Western Blotting (WB)
(169), (104), (73), (40), (39), (36), (22), (11), (8), (7), (7), (4), (2), (1)
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Product Details anti-PTPN6 Antibody

Target Details PTPN6 Application Details Handling Images
Specificity This antibody recognizes single 67 kDa PTP1-C in Human cells that express the enzyme and the SH2(C) domain
Characteristics Synonyms: PTPN-6, HCP, PTP1C, EC=3.1.3.48, Protein-tyrosine phosphatase 1C, PTP-1C, SH-PTP1,Protein-tyrosine phosphatase SHP-1, Hematopoietic cell protein-tyrosine phosphatase,Tyrosine-protein phosphatase non-receptor type 6
Purification Affinity chromatography on Protein G
Immunogen Purified recombinant protein corresponding to full-length PTP1-C
Clone PTY15
Isotype IgG1
Plasmids, Primers & others

Target Details PTPN6

Product Details anti-PTPN6 Antibody Application Details Handling Images back to top
Antigen
Alternative Name PTPN6 (PTPN6 Antibody Abstract)
Background The phosphorylation state of receptors and signal transduction molecules influences almost every cell activities. The phosphorylation rate is regulated by kinases which add phosphate group and by phosphatases which remove phosphate group form the amino acid residues on protein molecules. Protein tyrosine phosphatase 1 C (PTP1C) is a tyrosine phosphatase highly expressed in heomatopoietic cells. PTP1C was found to co-precipitate with B lymphocytespecific cell surface glycoprotein CD22, after anti-immunoglobulin stimulation. Study with PTP1C deficient mice showed that the phosphatase may implicate with negative selection in B cell immunity.Synonyms: HCP, Hematopoietic cell protein-tyrosine phosphatase, PTP-1C, PTP1C, PTPN-6, Protein-tyrosine phosphatase 1C, Protein-tyrosine phosphatase SHP-1, SH-PTP1, Tyrosine-protein phosphatase non-receptor type 6
Gene ID 5777
UniProt P29350
Pathways JAK-STAT Signaling, TCR Signaling, TLR Signaling, Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2

Application Details

Product Details anti-PTPN6 Antibody Target Details PTPN6 Handling Images back to top
Application Notes ELISA. Western Blot. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-PTPN6 Antibody Target Details PTPN6 Application Details Images back to top
Reconstitution Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL.
Buffer 0.01 M PBS, pH 7.2 without preservatives
Preservative Without preservative
Storage -20 °C
Storage Comment Prior to and following reconstitution store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Expiry Date 12 months