anti-Human PTPN6 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended PTPN6 Antibody (supplied by: Log in to see )

Antigen
Protein-tyrosine Phosphatase 1C (PTPN6) Antibodies
  • HCPH
  • HPTP1C
  • PTP-1C
  • SH-PTP1
  • SHP-1
  • SHP-1L
  • SHP1
  • DRPLA
  • Hcph
  • Ptp1C
  • me
  • motheaten
  • Ptph6
  • Shp-1
  • fj22f05
  • wu:fj22f05
  • zgc:55501
  • ptpn6
  • protein tyrosine phosphatase, non-receptor type 6
  • protein tyrosine phosphatase, non-receptor type 6 L homeolog
  • PTPN6
  • Ptpn6
  • ptpn6
  • ptpn6.L
Epitope
AA 247-277, Center
37
26
15
10
9
5
4
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human
231
101
92
5
4
2
2
2
1
1
1
1
1
Host
Rabbit
156
41
35
Clonality
Polyclonal
Conjugate
This PTPN6 antibody is un-conjugated
9
9
8
3
3
3
3
3
3
3
3
3
3
3
3
3
2
1
Application
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
169
104
73
39
39
36
22
11
8
8
7
5
2
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Available images

Catalog No. ABIN1882123
$ 335.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
11.5 ABIN5586488 IF IHC (p) Rabbit pTyr536 Log in to see Polyclonal 1
11.117387 ABIN711626 IF (p) IHC (p) WB Rabbit IgG pTyr536 Log in to see Polyclonal 0
10 ABIN197592 IF IHC (p) WB Rabbit Tyr536 Log in to see Polyclonal 4
10 ABIN5531900 IF IHC (p) WB Rabbit Ig Fraction AA 247-277 Log in to see Polyclonal 0
10 ABIN5586497 IF IHC (p) WB Rabbit IgG Log in to see Polyclonal 0
7 ABIN319255 IF IHC (p) Rabbit pTyr536 Log in to see Polyclonal 4
7 ABIN957753 ELISA IHC IHC (p) WB Mouse IgG1, kappa Log in to see 14D5 0
7 ABIN271911 IHC (p) WB Rabbit Log in to see Polyclonal 0
7 ABIN5586495 ELISA IHC (p) WB Rabbit Log in to see Polyclonal 0
7 ABIN5774108 ELISA IHC (p) WB Mouse IgG1 kappa Log in to see 14D5 0
7 ABIN5586496 IF IHC (p) WB Rabbit Log in to see Polyclonal 0
4 ABIN1103855 ELISA IHC IHC (p) WB Goat AA 553-564 Log in to see Polyclonal 0
4 ABIN957800 ELISA IHC IHC (p) WB Mouse IgG1, kappa Log in to see 0
4 ABIN954377 EIA IHC (p) WB Mouse IgG1 Log in to see 14D5 0
4 ABIN1804594 IHC IHC (p) WB Mouse IgG2b, kappa Log in to see 1SH01 0
4 ABIN711641 IF (p) IHC (p) WB Rabbit IgG pSer591 Log in to see Polyclonal 0
4 ABIN1738601 IHC (p) ELISA WB Goat Internal Region Log in to see Polyclonal 0
4 ABIN1724482 IHC (p) ELISA WB Mouse IgG1 kappa Log in to see 14D5 0
4 ABIN1724483 IHC (p) ELISA WB Mouse IgG1 kappa Log in to see 0
1 ABIN264440 IHC (p) IP WB Mouse IgG2b Log in to see 1SH01 5

General

Antigen Protein-tyrosine Phosphatase 1C (PTPN6) Antibodies
Epitope AA 247-277, Center
(37), (26), (15), (10), (9), (5), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(231), (101), (92), (5), (4), (2), (2), (2), (1), (1), (1), (1), (1)
Host Rabbit
(156), (41), (35)
Clonality (Clone)
Polyclonal   ( )
Conjugate This PTPN6 antibody is un-conjugated
(9), (9), (8), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (1)
Application Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(169), (104), (73), (39), (39), (36), (22), (11), (8), (8), (7), (5), (2), (1)
Pubmed 2 references available
Supplier Log in to see

Product Details anti-PTPN6 Antibody

Target Details PTPN6 Application Details Handling References for anti-PTPN6 antibody (ABIN1882123) Images
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. Purified Rabbit Polyclonal Antibody (Pab)
Immunogen This PTPN6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 247-277 amino acids from the Central region of human PTPN6.
Clone RB17225
Plasmids, Primers & others

Target Details PTPN6

Product Details anti-PTPN6 Antibody Application Details Handling References for anti-PTPN6 antibody (ABIN1882123) Images back to top
Antigen
Alternative Name PTPN6 (PTPN6 Antibody Abstract)
Background PTPN6 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling.

Synonyms: PTPN6, HCP, PTP1C, Tyrosine-protein phosphatase non-receptor type 6, Hematopoietic cell protein-tyrosine phosphatase, Protein-tyrosine phosphatase 1C, Protein-tyrosine phosphatase SHP-1, SH-PTP1
NCBI Accession NP_002822, NP_536859, NP_536858
UniProt P29350
Pathways JAK-STAT Signaling, TCR Signaling, TLR Signaling, Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2

Application Details

Product Details anti-PTPN6 Antibody Target Details PTPN6 Handling References for anti-PTPN6 antibody (ABIN1882123) Images back to top
Application Notes IF: 1:100,WB: 1:1000,IHC (p): 1:10-50
Restrictions For Research Use only

Handling

Product Details anti-PTPN6 Antibody Target Details PTPN6 Application Details References for anti-PTPN6 antibody (ABIN1882123) Images back to top
Format Liquid
Concentration 2 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

References for anti-PTPN6 antibody (ABIN1882123)

Product Details anti-PTPN6 Antibody Target Details PTPN6 Application Details Handling Images back to top
Product cited in:

Korporaal, Koekman, Verhoef, van der Wal, Bezemer, Van Eck, Akkerman: "Downregulation of platelet responsiveness upon contact with LDL by the protein-tyrosine phosphatases SHP-1 and SHP-2." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 29, Issue 3, pp. 372-9, 2009

Cho, Oh, Zhu: "Tyrosine phosphatase SHP-1 in oxidative stress and development of allergic airway inflammation." in: American journal of respiratory cell and molecular biology, Vol. 39, Issue 4, pp. 412-9, 2008

Images

Product Details anti-PTPN6 Antibody Target Details PTPN6 Application Details Handling References for anti-PTPN6 antibody (ABIN1882123) back to top
Supplier Images
Immunofluorescence (IF) image for anti-Protein-tyrosine Phosphatase 1C (PTPN6) (AA 247-277), (Center) antibody (ABIN1882123) Western blot analysis of PTPN6 Antibody (Center) (ABIN1882123) in HL-60 cell line lys...
Western Blotting (WB) image for anti-Protein-tyrosine Phosphatase 1C (PTPN6) (AA 247-277), (Center) antibody (ABIN1882123) Western blot analysis of PTPN6 Antibody (Center) (ABIN1882123) in HL-60 cell line lys...
Western Blotting (WB) image for anti-Protein-tyrosine Phosphatase 1C (PTPN6) (AA 247-277), (Center) antibody (ABIN1882123) Western blot analysis of PTPN6 Antibody (Center) (ABIN1882123) in HL-60 cell line lys...