KIR2DL5B Products
(Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 5B (KIR2DL5B))
Categories
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules\\; thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq, Jul 2008].
antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.
Featured KIR2DL5B Categories
KIR2DL5B Antibodies
High quality antibodies with extensive validation data.
KIR2DL5B Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended KIR2DL5B Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, FACS, IHC (p)
Validations
- (3)
Cat. No.
ABIN652855
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IF
Validations
- (1)
Cat. No.
ABIN7183707
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB, IF
Validations
Cat. No.
ABIN7186155
Quantity
100 μg
Datasheet
Datasheet
Recommended KIR2DL5B Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
Cat. No.
ABIN3082500
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
Cat. No.
ABIN3082501
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Insect Cells
Validations
Cat. No.
ABIN3104063
Quantity
1 mg
Datasheet
Datasheet
Synonyms and alternative names related to KIR2DL5B
killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 5B (KIR2DL5B), KIR2DL5, KIR2DL5.2, KIR2DLXProtein level used designations for KIR2DL5B
- CD158 antigen-like family member F2
- killer cell Ig-like receptor
- killer cell immunoglobulin-like receptor 2DL5B
- killer cell immunoglobulin-like receptor 2DLX
You are here:
