TRKB ELISA Kit

Catalog No. ABIN2042712

Product Details TRKB ELISA Kit

Target: TRKB (NTRK2) (Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2))

Reactivity: Mouse

Detection Method: Colorimetric

Method Type: Sandwich ELISA

Detection Range: 93.8-6000 pg/mL

Minimum Detection Limit: 93.8 pg/mL

Application: ELISA

Brand: BioAssay™

Cross-Reactivity (Details): There is no detectable cross-reactivity with other relevant proteins.

Sensitivity: < 5 pg/mL

Components: 96-well plate pre-coated with anti-TrkB, Mouse
Lyophilized recombinant TrkB, Mouse standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL

Application Details

Plate: Pre-coated

Protocol: Sandwich ELISA quantitative detection kit for Mouse trkB in cell culture supernates, cell lysates and tissue homogenates.TrkB receptor also known as TrkB tyrosine kinase or BDNF/NT-3 growth factors receptor or neurotrophic tyrosine kinase, receptor, type 2 is a protein that in humans is encoded by the NTRK2 gene.[1] TrkB is the high affinity catalytic receptor for several "neurotrophins", which are small protein growth factors that induce the survival and differentiation of distinct cell populations. The TrkB receptor is part of the large family of receptor tyrosine kinases. A "tyrosine kinase" is an enzyme which is capable of adding a phosphate group to certain tyrosines on target proteins, or "substrates".Soppet et al. [2] demonstrated that the gp145 gene product of the TRKB gene is rapidly phosphorylated on tyrosine residues upon exposure to BDNF and NTF3. The standard product used in this kit is recombinant TrkB, a 49.5kD glycoprotein, C32-H439.

Restrictions: For Research Use only

Handling

Storage: 4 °C/-20 °C

Target Details for TRKB

Target: TRKB (NTRK2) (Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2))

Alternative Name: TrkB (NTRK2 Products)

Synonyms: trkb ELISA Kit, trkb-b ELISA Kit, xtrkb ELISA Kit, si:ch211-220b11.1 ELISA Kit, trkB2 ELISA Kit, NTRK2 ELISA Kit, ntrk2 ELISA Kit, gp145-trkb ELISA Kit, TRKB ELISA Kit, GP145-TrkB ELISA Kit, trk-B ELISA Kit, AI848316 ELISA Kit, C030027L06Rik ELISA Kit, Tkrb ELISA Kit, trkB ELISA Kit, RATTRKB1 ELISA Kit, TRKB1 ELISA Kit, Trk-B ELISA Kit, TrkB ELISA Kit, neurotrophic receptor tyrosine kinase 2 ELISA Kit, neurotrophic receptor tyrosine kinase 2 L homeolog ELISA Kit, neurotrophic tyrosine kinase, receptor, type 2b ELISA Kit, neurotrophic receptor tyrosine kinase 2 S homeolog ELISA Kit, neurotrophic tyrosine kinase, receptor, type 2 ELISA Kit, NTRK2 ELISA Kit, ntrk2.L ELISA Kit, ntrk2b ELISA Kit, ntrk2.S ELISA Kit, ntrk2 ELISA Kit, Ntrk2 ELISA Kit

Gene ID: 18212

UniProt: P15209

Pathways: RTK Signaling, Neurotrophin Signaling Pathway, cAMP Metabolic Process, Skeletal Muscle Fiber Development, Feeding Behaviour, Dicarboxylic Acid Transport