Interferon gamma ELISA Kit
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- Target See all Interferon gamma (IFNG) ELISA Kits
- Interferon gamma (IFNG)
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Reactivity
- Mouse
- Detection Method
- Colorimetric
- Method Type
- Sandwich ELISA
- Minimum Detection Limit
- 0.762 pg/mL
- Application
- ELISA
- Purpose
- The Mouse IFN-γ ELISA Kit II is for the quantitative determination of mouse IFN-γ in serum, plasma, and cell culture supernatant.
- Brand
- BD OptEIA™
- Sample Type
- Serum, Plasma, Cell Culture Supernatant
- Analytical Method
- Quantitative
- Featured
- Discover our best selling IFNG ELISA Kit
- Top Product
- Discover our top product IFNG ELISA Kit
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- Application Notes
- The BD Biosciences Pharmingen recombinant mouse IFN-γ presents as a 30 kD homodimeric protein, as shown by SDS-PAGE analysis.
- Comment
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BD OptEIA™ Mouse IFN-γ ELISA Kit II
- Plate
- Pre-coated
- Restrictions
- For Research Use only
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- Handling Advice
- Interferon-γ (IFN-γ) is a potent multifunctional cytokine which is secreted by activated NK cells and CD4+TCRαβ+, CD8+TCRαβ+, and TCRγδ+ T cells and exerts its biological effects through specific binding to a single class of high affinity receptors. In addition to its antiviral effects, IFN-γ can upregulate a number of lymphoid cell functions including the antimicrobial and antitumor responses of macrophages, NK cells, and neutrophils. IFN-γ exerts strong regulatory influences on the proliferation, differentiation, and effector responses of B cell and T cell subsets. These influences can involve IFN-γ's capacity to boost MHC class I and II expression MHC class I and II expression by antigen-presenting cells as well as direct effects on B cells and T cells themselves.
- Storage
- 4 °C
- Storage Comment
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1. Store unopened kit at 2 - 8°C. Do not use kit after expiration date.
2. Before use, bring all reagents to room temperature (18 - 25°C). Immediately after use, return to proper storage conditions.
3. Lyophilized standards are stable until kit expiration date. After reconstitution, use freshly reconstituted standard within 12 hours (stored at 2 - 8°C).
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The molecular cell biology of interferon-gamma and its receptor." in: Annual review of immunology, Vol. 11, pp. 571-611, (1993) (PubMed).
: "Cloning and expression of murine immune interferon cDNA." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 80, Issue 19, pp. 5842-6, (1983) (PubMed).
: "Rapid, quantitative, semiautomated assay for virus-induced and immune human interferons." in: Journal of clinical microbiology, Vol. 12, Issue 3, pp. 433-8, (1981) (PubMed).
: "
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The molecular cell biology of interferon-gamma and its receptor." in: Annual review of immunology, Vol. 11, pp. 571-611, (1993) (PubMed).
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- Target See all Interferon gamma (IFNG) ELISA Kits
- Interferon gamma (IFNG)
- Alternative Name
- IFN-gamma (IFNG Products)
- Synonyms
- IFG ELISA Kit, IFI ELISA Kit, IFN-g ELISA Kit, Ifg ELISA Kit, IFNG2 ELISA Kit, IFN-gamma ELISA Kit, IFN-G ELISA Kit, IFNG ELISA Kit, IFNgamma ELISA Kit, TCRalpha ELISA Kit, INF-G ELISA Kit, ifng ELISA Kit, interferon gamma ELISA Kit, interferon, gamma 1-2 ELISA Kit, IFNG ELISA Kit, Ifng ELISA Kit, ifng1-2 ELISA Kit
- Background
- Interferon-γ (IFN-γ) is a potent multifunctional cytokine which is secreted by activated NK cells and CD4+TCRαβ+, CD8+TCRαβ+, and TCRγδ+ T cells and exerts its biological effects through specific binding to a single class of high affinity receptors. In addition to its antiviral effects, IFN-γ can upregulate a number of lymphoid cell functions including the antimicrobial and antitumor responses of macrophages, NK cells, and neutrophils. IFN-γ exerts strong regulatory influences on the proliferation, differentiation, and effector responses of B cell and T cell subsets. These influences can involve IFN-γ's capacity to boost MHC class I and II expression MHC class I and II expression by antigen-presenting cells as well as direct effects on B cells and T cells themselves.
- Pathways
- Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy
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