KLC1 Products
(Kinesin Light Chain 1 (KLC1))
Categories
Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named 'kinesin 2', this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos\; however, the full-length nature and/or biological validity of most of these variants have not been determined. [provided by RefSeq, Jul 2008].
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Featured KLC1 Categories
KLC1 Antibodies
High quality antibodies with extensive validation data.
KLC1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended KLC1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7434992
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS, IHC (p)
Validations
- (1)
- (4)
Cat. No.
ABIN652577
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (2)
- (3)
Cat. No.
ABIN2854634
Quantity
100 μL
Datasheet
Datasheet
Recommended KLC1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6957313
Quantity
96 tests
Datasheet
Datasheet
Recommended KLC1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3082565
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3132110
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7396514
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our KLC1 products
: "Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle." in: Scientific reports, Vol. 9, Issue 1, pp. 14202, (2019) (PubMed).: "Vaccinia virus protein complex F12/E2 interacts with kinesin light chain isoform 2 to engage the kinesin-1 motor complex." in: PLoS pathogens, Vol. 11, Issue 3, pp. e1004723, (2015) (PubMed).
: "Alterations in axonal transport motor proteins in sporadic and experimental Parkinson's disease." in: Brain : a journal of neurology, Vol. 135, Issue Pt 7, pp. 2058-73, (2012) (PubMed).
Synonyms and alternative names related to KLC1
kinesin family member 2A (KIF2A), kinesin light chain 1 (KLC1), kinesin light chain 1 (Klc1), kinesin light chain 1b (klc1b), kinesin light chain 1a (klc1a), kinesin light chain 1 (klc1), kinesin light chain 1 L homeolog (klc1.L), AI874768, HK2, KIF2, kinesin-II, KLC, klc, klc1, Klc2, KNS2, Kns2, kns2, KNS2A, kns2a, wu:fj17e04, zgc:55666, zgc:66299, zgc:77660Protein level used designations for KLC1
- Kinesin, heavy chain, 2
- kinesin-2
- kinesin-like protein KIF2A
- KLC 1
- kinesin 2 60/70kDa
- medulloblastoma antigen MU-MB-2.50
- kinesin 2
- kinesin light chain 1
- kinesin light chain 2
- kinesin light chain 4
- kinesin ii
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