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Human Polyclonal CNTRL Primary Antibody for IP, WB - ABIN253205
DAngiolella, Donato, Vijayakumar, Saraf, Florens, Washburn, Dynlacht, Pagano: SCF(Cyclin F) controls centrosome homeostasis and mitotic fidelity through CP110 degradation. in Nature 2010
Show all 3 Pubmed References
CNTRL and FGFR1 have roles in myeloid and lymphoid malignancies in both human and mouse models
CEP110 is essential for the reformation of specific aspects of the interphase centrosome architecture following mitosis as well as being required for the centrosome to function as a MTOC.
We propose that centriolin anchors protein complexes required for vesicle targeting and fusion and integrates membrane-vesicle fusion with abscission.
Centriolin depletion affects spindle size and peripheral spindle migration in oocytes.
This gene encodes a centrosomal protein required for the centrosome to function as a microtubule organizing center. The gene product is also associated with centrosome maturation. One version of stem cell myeloproliferative disorder is the result of a reciprocal translocation between chromosomes 8 and 9, with the breakpoint associated with fibroblast growth factor receptor 1 and centrosomal protein 1.
centrosomal protein 110kDa
, 110 kDa centrosomal protein
, bA165P4.1 (ortholog of mouse Ma2a8)
, bA165P4.2 (centrosomal protein 1)
, centriole associated protein
, centrosomal protein of 110 kDa
, centrosomal protein 1
, centrosomal protein 110
, antigen identified by monoclonal antibody 2A8