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Hhex (show HHEX Antibodies) and Cer1 are indispensable components of the Sox17 (show SOX17 Antibodies) pathway for cardiopoiesis.
regulates the Nodal/Bone Morphogenetic Protein antagonist Cerberus and the Baf60c/Smarcd3 (show SMARCD3 Antibodies) subunit of the Brg1 (show SMARCA4 Antibodies)/Brm (show SMARCA2 Antibodies)-associated factors (BAF (show BANF1 Antibodies)) chromatin-remodelling complex
a good marker for quantification of definitive endoderm differentiation of mouse and human ES/iPS cells
Role of Cerberus-like in mouse embryogenesis
Cerberus-like and Lefty-1 (show LEFTY1 Antibodies) function redundantly to modulate Nodal signaling during gastrulation and regulate patterning of the primitive streak
Some early Cer1-expressing cells do contribute to the AVE when it becomes established at E5.5.
successful identification of an association with CER1 in humans together with our mouse study suggests that CER1 may play a role in the development of bone or its metabolism
Cerberus binds and inhibits Nodal, Activin B (show Actbeta Antibodies), BMP-6 (show BMP6 Antibodies), and BMP-7 (show BMP7 Antibodies) but not BMP-2 (show BMP2 Antibodies) or Activin A (show INHBA Antibodies).
No significant association between the studied DKK1 (show DKK1 Antibodies) variations and osteoporosis was found, while CER1 variations seem to play a significant role in the determination of osteoporosis, combined with bone markers, in postmenopausal osteoporotic women.
results show that Cer1 (or CER1) serves as a good marker for quantification of definitive endoderm differentiation of mouse and human ES/iPS (show SLC27A4 Antibodies) cells
CER1 gene variations play a significant role in determining BMD (show BEST1 Antibodies) and vertebral or hip fractures, which might be helpful in clinical practice to identify patients with increased fracture risk
Chordin (show CHRD Antibodies), Noggin (show NOG Antibodies), beta-Catenin (show CTNNB1 Antibodies), and Cerberus have roles in neural induction in Xenopus
Cardiogenesis in mesoderm depends on Nodal-mediated induction of Cerberus in underlying endoderm.
This gene encodes a cytokine member of the cysteine knot superfamily, characterized by nine conserved cysteines and a cysteine knot region. The cerberus-related cytokines, together with Dan and DRM/Gremlin, represent a group of bone morphogenetic protein (BMP) antagonists that can bind directly to BMPs and inhibit their activity.
cerberus-related protein 1
, cerberus 1, cysteine knot superfamily
, cerberus 1, cysteine knot superfamily, homolog (Xenopus laevis)
, cerberus 1, cysteine knot superfamily, homolog
, Cerberus-related protein
, U-box protein
, cerberus homolog
, cerberus-like protein
, cerberus-related protein
, cerberus 1 homolog, cysteine knot superfamily
, DAN domain family member 4
, cerberus-related 1