Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
Alternative names and synonyms associated with HDAC3
Histone deacetylase 3 (HDAC3) ELISA Kit
histone deacetylase 3 (hdac3) ELISA Kit
histone deacetylase 3 (CNL05260) ELISA Kit
histone deacetylase 3 (HDAC3) ELISA Kit
histone deacetylase 3 (Hdac3) ELISA Kit
histone deacetylase 3 S homeolog (hdac3.S) ELISA Kit