anti-Primate CD40 Ligand antibody for Functional Studies

Recommended CD40 Ligand Antibody (supplied by: Log in to see )

Antigen
CD40 Ligand (CD40LG) Antibodies
  • CD154
  • cd40l
  • CD40L
  • HIGM1
  • IGM
  • IMD3
  • T-BAM
  • TNFSF5
  • TRAP
  • gp39
  • hCD40L
  • CD40-L
  • Cd40l
  • Ly-62
  • Ly62
  • Tnfsf5
  • CD40 ligand
  • TNF superfamily member 5
  • CD40LG
  • cd40l
  • Cd40lg
  • LOC100358388
  • CD154
Reactivity
Human, Primate
493
252
55
20
20
10
8
8
6
5
4
3
3
3
2
2
2
1
Host
Mouse
302
175
111
51
45
28
2
1
Clonality
Monoclonal
Conjugate
This CD40 Ligand antibody is un-conjugated
75
61
46
17
17
15
15
11
9
9
9
9
9
9
9
8
8
7
7
7
7
6
4
4
4
2
2
2
2
2
2
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Functional Studies (Func), Immunocytochemistry (ICC), Immunofluorescence (IF)
434
298
173
109
68
64
50
42
33
20
17
17
13
13
9
9
6
5
4
4
2
2
2
1
1
1
1
1
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Catalog No. ABIN5540106
$ 242.55
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN5540105 FACS Func ICC IF Mouse IgG1 Log in to see 24-31

General

Antigen CD40 Ligand (CD40LG) Antibodies
Reactivity Human, Primate
(493), (252), (55), (20), (20), (10), (8), (8), (6), (5), (4), (3), (3), (3), (2), (2), (2), (1)
Host Mouse
(302), (175), (111), (51), (45), (28), (2), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This CD40 Ligand antibody is un-conjugated
(75), (61), (46), (17), (17), (15), (15), (11), (9), (9), (9), (9), (9), (9), (9), (8), (8), (7), (7), (7), (7), (6), (4), (4), (4), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Functional Studies (Func), Immunocytochemistry (ICC), Immunofluorescence (IF)
(434), (298), (173), (109), (68), (64), (50), (42), (33), (20), (17), (17), (13), (13), (9), (9), (6), (5), (4), (4), (2), (2), (2), (1), (1), (1), (1), (1)
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Product Details anti-CD40 Ligand Antibody

Target Details CD40 Ligand Application Details Handling Images
Specificity This antibody detects CD154 / CD40L (CD40-ligand), a 39 kDa cell surface type II glycoprotein expressed predominantly on activated CD4+ lymphocytes.
Purification Protein-A affinity chromatography (> 95% pure by SDS-PAGE)
Immunogen Human CD154 fusion protein
Clone 24-31
Isotype IgG1

Target Details CD40 Ligand

Product Details anti-CD40 Ligand Antibody Application Details Handling Images back to top
Antigen
Alternative Name cd154,cd40l (CD40LG Antibody Abstract)
Background CD154 / CD40L (CD40 ligand) is a member of the tumor necrosis factor family, and is expressed primarily on activated CD4+ lymphocytes, but also on mast cells, basophils, eosinophils and human dendritic cells. Its counter-receptor CD40 is expressed on antigen presenting cells, including dendritic cells, macrophages, and B cells, and also on fibroblasts. Triggering of CD40 by CD40L causes maturation of dendritic cells and upregulation of antigen presentation in functions of the MHC and costimulatory molecules. CD40L also functions as a direct stimulating factor for T cells. CD40L plays also roles e.g. in antibody class switching and modulation of apoptosis in the germinal center.
UniProt P29965
Pathways NF-kappaB Signaling, Production of Molecular Mediator of Immune Response

Application Details

Product Details anti-CD40 Ligand Antibody Target Details CD40 Ligand Handling Images back to top
Application Notes Flow cytometry. Immunocytochemistry. Functional application: blocking.
Restrictions For Research Use only

Handling

Product Details anti-CD40 Ligand Antibody Target Details CD40 Ligand Application Details Images back to top
Format Liquid
Buffer 95 % pure by SDS-PAGE) Buffer System: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
Expiry Date 12 months