anti-Human IKBKB antibody for Dot Blot

Recommended IKBKB Antibody (supplied by: Log in to see )

Antigen
Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) Antibodies
  • ikk-beta
  • ikk2
  • ikkb
  • ikkbeta
  • IKBKB
  • IKKB
  • CG4201
  • DIK
  • DLAK
  • DmIKK
  • DmIKKBeta
  • DmIKKb
  • DmIKKbeta
  • DmIkkbeta
  • Dmel\\CG4201
  • Dmikkb
  • Dmikkbeta
  • IK
  • IKK
  • IKK-beta
  • IKKb
  • IKKbeta
  • IRD-5
  • IRD5
  • Ik
  • Ikkb
  • Ikkbeta
  • Ird-5
  • Ird5
  • LRK
  • Lak
  • anon-89Bd
  • dIKK
  • dIKK-beta
  • dIKKbeta
  • dLak
  • dmIKKbeta
  • ikk
  • ird
  • ird5/DmIkk[beta]
  • IKK2
  • NFKBIKB
  • AIM-1
  • AI132552
  • IKK-2
  • IKK[b]
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta L homeolog
  • inhibitor of nuclear factor kappa B kinase subunit beta
  • I-kappaB kinase beta
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
  • inhibitor of kappaB kinase beta
  • ikbkb.L
  • IKBKB
  • ikbkb
  • IKKbeta
  • Ikbkb
Epitope
pSer177
58
33
29
23
21
20
20
20
20
20
20
20
20
19
19
19
19
17
17
17
15
8
8
7
7
7
6
6
5
4
4
4
3
3
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
685
227
159
22
13
7
7
6
5
4
1
1
Host
Rabbit
577
122
9
2
Clonality
Polyclonal
Conjugate
This IKBKB antibody is un-conjugated
38
37
37
33
33
31
9
7
5
5
5
5
5
5
5
5
5
2
2
2
2
2
2
2
2
2
2
Application
Dot Blot (DB)
341
308
263
107
82
78
68
43
37
33
6
6
6
5
3
3
3
2
1
Options
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Catalog No. ABIN1881450
$ 324.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
28.901054 ABIN1881451 DB Rabbit pThr180 Log in to see Polyclonal 5
28.901054 ABIN1539709 DB Rabbit Ig pSer675 Log in to see Polyclonal 0
28.901054 ABIN1539705 DB Rabbit Ig pSer466 Log in to see Polyclonal 0
28.901054 ABIN1539707 DB Rabbit Ig pSer670 Log in to see Polyclonal 0
28.901054 ABIN1881453 DB Rabbit pTyr609 Log in to see Polyclonal 5
28.901054 ABIN1881449 DB Rabbit pSer733 Log in to see Polyclonal 5
28.901054 ABIN1539710 DB Rabbit Ig pSer689 Log in to see Polyclonal 0
28.901054 ABIN1539772 DB Rabbit Ig pSer697 Log in to see Polyclonal 0
28.901054 ABIN3031303 DB ELISA Rabbit Ig Fraction pSer670 Log in to see Polyclonal 0
28.901054 ABIN3031302 DB ELISA Rabbit Ig Fraction pSer466 Log in to see Polyclonal 0
28.901054 ABIN3031312 DB ELISA Rabbit Ig Fraction pSer675 Log in to see Polyclonal 0
28.901054 ABIN3031304 DB ELISA Rabbit Ig Fraction pSer672 Log in to see Polyclonal 0
28.901054 ABIN3031311 DB ELISA Rabbit Ig Fraction pSer177 Log in to see Polyclonal 0
28.901054 ABIN3031317 DB ELISA Rabbit Ig Fraction pThr180 Log in to see Polyclonal 0
28.901054 ABIN3031308 DB ELISA Rabbit Ig Fraction pTyr609 Log in to see Polyclonal 0
28.901054 ABIN3031305 DB ELISA Rabbit Ig Fraction pSer682 Log in to see Polyclonal 0
28.901054 ABIN3031313 DB ELISA Rabbit Ig Fraction pSer689 Log in to see Polyclonal 0
28.901054 ABIN3031315 DB ELISA Rabbit Ig Fraction pSer697 Log in to see Polyclonal 0
28.901054 ABIN3031307 DB ELISA Rabbit Ig Fraction pSer733 Log in to see Polyclonal 0
28.901054 ABIN3031306 DB ELISA Rabbit Ig Fraction pSer705 Log in to see Polyclonal 0

General

Antigen Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) Antibodies
Epitope pSer177
(58), (33), (29), (23), (21), (20), (20), (20), (20), (20), (20), (20), (20), (19), (19), (19), (19), (17), (17), (17), (15), (8), (8), (7), (7), (7), (6), (6), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(685), (227), (159), (22), (13), (7), (7), (6), (5), (4), (1), (1)
Host Rabbit
(577), (122), (9), (2)
Clonality (Clone)
Polyclonal   ( )
Conjugate This IKBKB antibody is un-conjugated
(38), (37), (37), (33), (33), (31), (9), (7), (5), (5), (5), (5), (5), (5), (5), (5), (5), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Dot Blot (DB)
(341), (308), (263), (107), (82), (78), (68), (43), (37), (33), (6), (6), (6), (5), (3), (3), (3), (2), (1)
Pubmed 5 references available
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Product Details anti-IKBKB Antibody

Target Details IKBKB Application Details Handling References for anti-IKBKB antibody (ABIN1881450) Images
Predicted Reactivity Cow (Bovine),Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Immunogen This IKKB Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S177 of human IKKB.
Clone RB40664

Target Details IKBKB

Product Details anti-IKBKB Antibody Application Details Handling References for anti-IKBKB antibody (ABIN1881450) Images back to top
Antigen
Alternative Name IKKB (IKBKB Antibody Abstract)
Background NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008, or NFKBIB, MIM 604495), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664, or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T, R is an A or G purine, and Y is a C or T pyrimidine).

Synonyms: IKBKB, IKKB, Inhibitor of nuclear factor kappa-B kinase subunit beta, I-kappa-B kinase 2, Nuclear factor NF-kappa-B inhibitor kinase beta
NCBI Accession NP_001547, NP_001177649, NP_001229707
UniProt O14920
Pathways NF-kappaB Signaling, RTK Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Hepatitis C, Toll-Like Receptors Cascades

Application Details

Product Details anti-IKBKB Antibody Target Details IKBKB Handling References for anti-IKBKB antibody (ABIN1881450) Images back to top
Application Notes DB: 1:500
Restrictions For Research Use only

Handling

Product Details anti-IKBKB Antibody Target Details IKBKB Application Details References for anti-IKBKB antibody (ABIN1881450) Images back to top
Format Liquid
Concentration 0.45 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

References for anti-IKBKB antibody (ABIN1881450)

Product Details anti-IKBKB Antibody Target Details IKBKB Application Details Handling Images back to top
Product cited in:

Yatherajam, Banerjee, McCorkell, Solt, Hanson, Madge, Kang, Worley, Orange, May: "Cutting edge: association with I kappa B kinase beta regulates the subcellular localization of Homer3." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 5, pp. 2665-9, 2010

Kenneth, Mudie, Rocha: "IKK and NF-kappaB-mediated regulation of Claspin impacts on ATR checkpoint function." in: The EMBO journal, Vol. 29, Issue 17, pp. 2966-78, 2010

Zhao, Li, Chen: "CC2D1A, a DM14 and C2 domain protein, activates NF-kappaB through the canonical pathway." in: The Journal of biological chemistry, Vol. 285, Issue 32, pp. 24372-80, 2010

Niida, Tanaka, Kamitani: "Downregulation of active IKK beta by Ro52-mediated autophagy." in: Molecular immunology, Vol. 47, Issue 14, pp. 2378-87, 2010

Schuurhof, Bont, Siezen, Hodemaekers, van Houwelingen, Kimman, Hoebee, Kimpen, Janssen: "Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls." in: Pediatric pulmonology, Vol. 45, Issue 6, pp. 608-13, 2010

Images

Product Details anti-IKBKB Antibody Target Details IKBKB Application Details Handling References for anti-IKBKB antibody (ABIN1881450) back to top
Supplier Images
Dot Blot (DB) image for anti-Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB) (pSer177) antibody (ABIN1881450) Dot blot analysis of IKKB Antibody (Phospho S177) Phospho-specific Pab (ABIN1881450) ...