anti-Horse (Equine) IL1A antibody for Western Blotting

Recommended IL1A Antibody (supplied by: Log in to see )

Antigen
Interleukin 1 alpha (IL1A) Antibodies
  • IL-1A
  • IL1
  • IL1-ALPHA
  • IL1F1
  • Il-1a
  • IL-1 alpha
  • IL-1alpha
  • L1A
  • interleukin 1 alpha
  • IL1A
  • Il1a
Epitope
N-Term
31
10
10
10
10
10
9
8
7
7
6
5
5
5
5
5
4
4
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Goat, Horse (Equine), Human, Mouse (Murine), Rat (Rattus), Sheep (Ovine)
258
100
61
15
12
11
11
8
7
6
6
3
2
Host
Rabbit
250
140
35
9
9
6
3
2
1
Clonality
Polyclonal
Conjugate
This IL1A antibody is un-conjugated
80
30
15
13
10
8
2
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
352
243
129
55
46
40
39
27
25
23
23
19
9
7
2
2
2
2
1
1
1
1
1
1
1
1
1
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Catalog No. ABIN2785653
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.1357021 ABIN1172160 ICC IHC WB Rabbit IgG AA 95-269 Log in to see Polyclonal 0
3.1357021 ABIN3201252 ICC IHC (fro) IHC (p) ELISA WB Mouse IgG Log in to see 0
3.1357021 ABIN2935265 IF/ICC IHC IP WB Rabbit AA 95-269 Log in to see Polyclonal 0
3.1357021 ABIN6002451 IF/ICC IHC IP WB Mouse AA 95-269 Log in to see 0
3.1357021 ABIN6002453 IF/ICC IHC IP WB Mouse AA 95-269 Log in to see 0
3.1357021 ABIN6002445 IF/ICC IHC IP WB Mouse AA 95-269 Log in to see 0
3.1357021 ABIN5662285 WB Mouse AA 95-269 Log in to see 0
3.1357021 ABIN5662286 WB Mouse AA 95-269 Log in to see 0
1 ABIN2609599 WB Rabbit IgG AA 95-269 Log in to see Polyclonal 0
1 ABIN2609608 WB Biotin Rabbit IgG AA 95-269 Log in to see Polyclonal 0
1 ABIN2623958 WB FITC Rabbit IgG AA 95-269 Log in to see Polyclonal 0
1 ABIN1172162 IHC ELISA WB Biotin Rabbit IgG Log in to see Polyclonal 0
1 ABIN6050361 IF/ICC IHC WB Biotin Rabbit IgG Log in to see Polyclonal 0
1 ABIN6055783 IF/ICC IHC WB Biotin Mouse IgG Log in to see 0
1 ABIN6055719 IF/ICC IHC WB Biotin Mouse IgG Log in to see 0

General

Antigen Interleukin 1 alpha (IL1A) Antibodies
Epitope N-Term
(31), (10), (10), (10), (10), (10), (9), (8), (7), (7), (6), (5), (5), (5), (5), (5), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Goat, Horse (Equine), Human, Mouse (Murine), Rat (Rattus), Sheep (Ovine)
(258), (100), (61), (15), (12), (11), (11), (8), (7), (6), (6), (3), (2)
Host Rabbit
(250), (140), (35), (9), (9), (6), (3), (2), (1)
Clonality
Polyclonal
Conjugate This IL1A antibody is un-conjugated
(80), (30), (15), (13), (10), (8), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Western Blotting (WB)
(352), (243), (129), (55), (46), (40), (39), (27), (25), (23), (23), (19), (9), (7), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-IL1A Antibody

Target Details IL1A Application Details Handling References for anti-IL1A antibody (ABIN2785653) Images
Blocking Peptide Blocking peptide for this product available: ABIN978484
Sequence VSYGPLHEGC MDQSVSLSIS ETSKTSKLTF KESMVVVATN GKVLKKRRLS
Predicted Reactivity Cow: 92%, Dog: 85%, Goat: 85%, Horse: 93%, Human: 100%, Mouse: 79%, Rat: 79%, Sheep: 85%
Characteristics This is a rabbit polyclonal antibody against IL1A. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human IL1A
Plasmids, Primers & others

Target Details IL1A

Product Details anti-IL1A Antibody Application Details Handling References for anti-IL1A antibody (ABIN2785653) Images back to top
Antigen
Alternative Name IL1A (IL1A Antibody Abstract)
Background The IL1A protein is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. The gene encoding IL1A and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: IL-1A, IL1, IL1-ALPHA, IL1F1
Protein Interaction Partner: HFI1, AHC1, GCN5, SPT7, ADA2, NGG1, SPT8, HAX1, NFKBIE, IL1RAP, NDN, S100A13, IL1R2, IL1R1, IL1A, CAPN1,
Protein Size: 271
Molecular Weight 18 kDa
Gene ID 3552
NCBI Accession NM_000575, NP_000566
UniProt P01583
Pathways NF-kappaB Signaling, Autophagy

Application Details

Product Details anti-IL1A Antibody Target Details IL1A Handling References for anti-IL1A antibody (ABIN2785653) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 271 AA

Restrictions For Research Use only

Handling

Product Details anti-IL1A Antibody Target Details IL1A Application Details References for anti-IL1A antibody (ABIN2785653) Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-IL1A antibody (ABIN2785653)

Product Details anti-IL1A Antibody Target Details IL1A Application Details Handling Images back to top
Product cited in:

Wang, Jiang, Li, He, Zhao, Yang, Zhu, Yin, Li, Wang, Liu, Shang, Yang, Wang, Zhen, Zhang, Yu, Zhong, Ye, Huang, Yuan: "Shigella flexneri T3SS effector IpaH4.5 modulates the host inflammatory response via interaction with NF-?B p65 protein." in: Cellular microbiology, Vol. 15, Issue 3, pp. 474-85, 2013

Zheng, Humphry, Maguire, Bennett, Clarke: "Intracellular interleukin-1 receptor 2 binding prevents cleavage and activity of interleukin-1?, controlling necrosis-induced sterile inflammation." in: Immunity, Vol. 38, Issue 2, pp. 285-95, 2013

Background publications

Ikeda, Sasazuki, Natsukawa, Shaura, Koizumi, Kasuga, Ohnami, Sakamoto, Yoshida, Iwasaki, Tsugane: "Screening of 214 single nucleotide polymorphisms in 44 candidate cancer susceptibility genes: a case-control study on gastric and colorectal cancers in the Japanese population." in: The American journal of gastroenterology, Vol. 103, Issue 6, pp. 1476-87, 2008

Images

Product Details anti-IL1A Antibody Target Details IL1A Application Details Handling References for anti-IL1A antibody (ABIN2785653) back to top
Supplier Images
Western Blotting (WB) image for anti-Interleukin 1 alpha (IL1A) (N-Term) antibody (ABIN2785653) WB Suggested Anti-IL1A Antibody Titration: 0.2-1 ug/ml
Positive Control:...