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|Antigen||Interleukin 1 alpha (IL1A) Antibodies|
|Conjugate||This IL1A antibody is un-conjugated Alternatives|
Blocking Antibody (Inhibition), ELISA, Western Blotting (WB)
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Product Details anti-IL1A AntibodyTarget Details IL1A Application Details Handling Images
|Immunogen||IL1 alpha antibody was raised in rabbit using highly pure recombinant human IL-1-alpha as the immunogen.|
|Plasmids, Primers & others|
Target Details IL1AProduct Details anti-IL1A Antibody Application Details Handling Images back to top
|Alternative Name||IL1 alpha (IL1A Antibody Abstract)|
|Background||IL1a is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL1a and IL1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL2 release, B-cell maturation and proliferation, mitogenic FGFlike activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL1beta is a secreted cytokine, IL1a is predominantly a cell-associated cytokine.|
|Molecular Weight||17.7 kDa (predicted detection band MW)|
|Pathways||NF-kappaB Signaling, Autophagy|
Application DetailsProduct Details anti-IL1A Antibody Target Details IL1A Handling Images back to top
ELISA: 0.5-2 µg/mL, Inhibition: 1-2 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator.
|Restrictions||For Research Use only|
HandlingProduct Details anti-IL1A Antibody Target Details IL1A Application Details Images back to top
|Reconstitution||Reconstitute in sterile water at a concentration of >0.2 mg/mL.|
|Buffer||Lyophilized from PBS, pH 7.2.|
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.
|Storage Comment||Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.|