anti-Ferret Insulin antibody for Enzyme Immunoassay

Recommended Insulin Antibody (supplied by: Log in to see )

Antigen
Insulin (INS) Antibodies
  • ins1
  • xins
  • ins1-a
  • Insulin
  • IDDM2
  • ILPR
  • IRDN
  • MODY10
  • AA986540
  • Ins-2
  • InsII
  • Mody
  • Mody4
  • proinsulin
  • zgc:109842
  • insulin
  • insulin precursor
  • insulin II
  • preproinsulin
  • ins
  • PIN
  • INS
  • Ins
  • INS-IGF2
  • Ins2
Reactivity
Ferret, Human, Pig (Porcine), Rat (Rattus)
987
495
381
374
234
188
47
9
7
6
5
5
4
2
1
1
1
1
1
1
1
1
Host
Rabbit
818
195
50
16
3
1
Clonality
Polyclonal
Conjugate
This Insulin antibody is un-conjugated
53
43
38
28
27
22
22
19
17
17
15
14
14
14
14
14
14
14
9
9
9
8
8
8
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
5
2
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
501
389
279
278
251
235
188
118
106
67
66
31
25
23
21
8
7
6
5
4
4
3
2
1
1
1
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Catalog No. ABIN113504
$ 467.50
Plus shipping costs $45.00

General

Antigen Insulin (INS) Antibodies
Reactivity Ferret, Human, Pig (Porcine), Rat (Rattus)
(987), (495), (381), (374), (234), (188), (47), (9), (7), (6), (5), (5), (4), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Host Rabbit
(818), (195), (50), (16), (3), (1)
Clonality
Polyclonal
Conjugate This Insulin antibody is un-conjugated
(53), (43), (38), (28), (27), (22), (22), (19), (17), (17), (15), (14), (14), (14), (14), (14), (14), (14), (9), (9), (9), (8), (8), (8), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (2), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(501), (389), (279), (278), (251), (235), (188), (118), (106), (67), (66), (31), (25), (23), (21), (8), (7), (6), (5), (4), (4), (3), (2), (1), (1), (1), (1), (1), (1)
Pubmed 1 reference available
Supplier Log in to see

Product Details anti-Insulin Antibody

Target Details Insulin Application Details Handling References for anti-Insulin antibody (ABIN113504) Images
Specificity The antibody detects Insulin which is produced by the B-cells of the pancreatic islets. Antibody BP5053 can be used for the diagnosis of pancreatic B-cell tumors. Antigen localization: cytoplasm, extracellular.
Purification Serum
Immunogen Porcine insulin
Plasmids, Primers & others

Target Details Insulin

Product Details anti-Insulin Antibody Application Details Handling References for anti-Insulin antibody (ABIN113504) Images back to top
Antigen
Alternative Name Insulin (INS Antibody Abstract)
Background Insulin is one of the major regulatory hormones of intermediate metabolism throughout the body. The biological actions of this hormone involve integration of carbohydrate, protein, and lipid metabolism. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Immunocytochemical investigations have localized insulin in the B cells of pancreatic islets of Langerhans. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of B cell origin such as insulinoma.Synonyms: INS
Gene ID 3630
NCBI Accession NP_000198
UniProt P01308
Pathways NF-kappaB Signaling, RTK Signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation

Application Details

Product Details anti-Insulin Antibody Target Details Insulin Handling References for anti-Insulin antibody (ABIN113504) Images back to top
Application Notes ELISA. Immunohistochemistry on frozen and paraffin sections: proteolytic treatment is notrequired, optimal results have been obtained by using the autoclave or microwave retrievalmethod (with citrate buffer). For immunohistochemistry dilute 1: 50 - 1: 100 (with PBS or TBS immediately before use),based on the indirect method, with a normal ABC method the dilution can be up to 5xhigher when using the microwave retrieval method. Recommended positive control: Pancreas.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Insulin Antibody Target Details Insulin Application Details References for anti-Insulin antibody (ABIN113504) Images back to top
Format Liquid
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-Insulin antibody (ABIN113504)

Product Details anti-Insulin Antibody Target Details Insulin Application Details Handling Images back to top
Background publications

Luts, Sundler: "Peptide-containing nerve fibers in the respiratory tract of the ferret." in: Cell and tissue research, Vol. 258, Issue 2, pp. 259-67, 1990