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|Antigen||Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR) Antibodies|
|Epitope||AA 28-218 Alternatives|
|Reactivity||Mouse (Murine) Alternatives|
|Conjugate||This LTBR antibody is un-conjugated Alternatives|
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB)
|5 references available|
|Supplier||Log in to see|
Product Details anti-LTBR AntibodyTarget Details LTBR Application Details Handling References for anti-LTBR antibody (ABIN4900063) Images
|Specificity||Detects mouse Lymphotoxin beta R/TNFRSF3 in direct ELISA and Western blots. In direct ELISAs, approximately 5 % cross-reactivity with recombinant human (rh) LT beta R is observed, and less than 1 % cross-reactivity with recombinant mouse (rm) 4-1BB, rmCD27, rmOPG, rmRANK, rmCD30, rmCD40, rhDR6, rmTNF RI, rmTNF RII, rmEDAR, rmFas and rmGITR is observed.|
|Sterility||0.2 μm filtered|
|Immunogen||Mouse myeloma cell line NS0-derived recombinant mouse Lymphotoxin beta R/TNFRSF3, Ser28-Pro218, Accession # P50284|
Target Details LTBRProduct Details anti-LTBR Antibody Application Details Handling References for anti-LTBR antibody (ABIN4900063) Images back to top
|Alternative Name||LTBR (LTBR Antibody Abstract)|
|Background||Alternative Names: CD18, D12S370, ltbetar, LT-BETA-R, LTBR, lymphotoxin B receptor, lymphotoxin beta receptor (TNFR superfamily, member 3), Lymphotoxin-beta receptor, LymphotoxinbR, TNF RIII, TNF Rrp, TNFCRTNF-RIII, TNFR superfamily, member 3, TNFR2-RP, TNFR3, TNF-R-III, TNFR-RP, TNFRSF3, TNFRSF3TNFR-III, Tumor necrosis factor C receptor, Tumor necrosis factor receptor 2-related protein, tumor necrosis factor receptor superfamily member 3, tumor necrosis factor receptor superfamily, member 3, Tumor necrosis factor receptor type III|
|Research Area||Chromatin and Nuclear Signaling, Apoptosis/Necrosis|
Application DetailsProduct Details anti-LTBR Antibody Target Details LTBR Handling References for anti-LTBR antibody (ABIN4900063) Images back to top
Western Blot 0.1 μg/mL
Flow Cytometry 0.25 μg/10^6 cells
Immunohistochemistry 5-15 μg/mL
|Restrictions||For Research Use only|
HandlingProduct Details anti-LTBR Antibody Target Details LTBR Application Details References for anti-LTBR antibody (ABIN4900063) Images back to top
|Reconstitution||Reconstitute at 0.2 mg/mL in sterile PBS.|
|Buffer||Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.|
|Storage||4 °C,-20 °C,-80 °C|
|Storage Comment||Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.|
|Expiry Date||12 months|
References for anti-LTBR antibody (ABIN4900063)Product Details anti-LTBR Antibody Target Details LTBR Application Details Handling Images back to top
|Product cited in:||
Kumar, Dasoveanu, Chyou, Tzeng, Rozo, Liang, Stohl, Fu, Ruddle, Lu: "A dendritic-cell-stromal axis maintains immune responses in lymph nodes." in: Immunity, Vol. 42, Issue 4, pp. 719-30, 2015 Method employed by authors: Neutralization (Neut) (Sample species: Mouse (Murine)).
Baluk, Yao, Feng, Romano, Jung, Schreiter, Yan, Shealy, McDonald: "TNF-alpha drives remodeling of blood vessels and lymphatics in sustained airway inflammation in mice." in: The Journal of clinical investigation, Vol. 119, Issue 10, pp. 2954-64, 2009 Method employed by authors: Immunohistochemistry (Frozen Sections) (IHC (fro)) (Sample species: Mouse (Murine)).
Suto, Katakai, Sugai, Kinashi, Shimizu: "CXCL13 production by an established lymph node stromal cell line via lymphotoxin-beta receptor engagement involves the cooperation of multiple signaling pathways." in: International immunology, Vol. 21, Issue 4, pp. 467-76, 2009 Method employed by authors: Neutralization (Neut) (Sample species: Mouse (Murine)).
Katakai, Suto, Sugai, Gonda, Togawa, Suematsu, Ebisuno, Katagiri, Kinashi, Shimizu: "Organizer-like reticular stromal cell layer common to adult secondary lymphoid organs." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 9, pp. 6189-200, 2008 Method employed by authors: Biochemical Assay (BCA) (Sample species: Mouse (Murine)).
Katakai, Hara, Sugai, Gonda, Shimizu: "Lymph node fibroblastic reticular cells construct the stromal reticulum via contact with lymphocytes." in: The Journal of experimental medicine, Vol. 200, Issue 6, pp. 783-95, 2004 Method employed by authors: Flow Cytometry (FACS) (Sample species: Mouse (Murine)).
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