anti-Rat (Rattus) MAP3K7 antibody for Immunohistochemistry

Recommended MAP3K7 Antibody (supplied by: Log in to see )

Antigen
Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) Antibodies
  • si:ch211-225h9.1
  • zgc:110612
  • Tak1
  • MEKK7
  • TAK1
  • TGF1a
  • B430101B05
  • C87327
  • mitogen-activated protein kinase kinase kinase 7
  • mitogen activated protein kinase kinase kinase 7
  • map3k7
  • Map3k7
  • MAP3K7
Epitope
pThr187
34
20
14
13
11
10
10
10
8
7
6
5
4
4
4
4
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
199
81
66
5
5
4
4
4
3
3
3
2
2
1
1
1
1
Host
Rabbit
172
15
14
Clonality
Polyclonal
Conjugate
This MAP3K7 antibody is un-conjugated
10
10
10
9
9
9
Application
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
161
126
72
39
20
7
5
5
3
1
1
1
Supplier
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Catalog No. ABIN6256492
$ 390.77
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
16.13255 ABIN462440 IHC IHC (p) WB Rabbit AA 563-579 Log in to see Polyclonal 0
16.13255 ABIN6263109 ELISA ICC IF IHC WB Rabbit IgG Log in to see Polyclonal 0
16.13255 ABIN1848228 IHC ELISA WB Rabbit Thr187 Log in to see Polyclonal 0
13.25679 ABIN2140881 IHC ELISA WB Rabbit IgG pSer439 Log in to see Polyclonal 0
10.132549 ABIN1532056 IHC ELISA WB Rabbit IgG AA 411-460, pSer439 Log in to see Polyclonal 2
10.132549 ABIN1533087 IHC ELISA WB Rabbit IgG AA 161-210 Log in to see Polyclonal 1
10.132549 ABIN214285 IF IHC IHC (p) WB Rabbit IgG N-Term Log in to see Polyclonal 0
7.1325493 ABIN5959664 ELISA IHC Rabbit IgG Log in to see Polyclonal 0
7.1325493 ABIN5959665 ELISA IHC Rabbit IgG Log in to see Polyclonal 0
4 ABIN2878762 ELISA IHC IHC (p) WB Rabbit IgG AA 161-210 Log in to see Polyclonal 0
4 ABIN1842722 IHC WB Rabbit Log in to see Polyclonal 0
1 ABIN1450650 IHC ELISA WB Rabbit IgG AA 411-460 Log in to see Polyclonal 1
1 ABIN2887710 ELISA IHC IHC (p) WB Rabbit IgG AA 411-460 Log in to see Polyclonal 0
1 ABIN2884019 ELISA IHC IHC (p) WB Rabbit IgG pSer439 Log in to see Polyclonal 0
1 ABIN2893086 IHC IHC (p) WB Rabbit Asp181 Log in to see Polyclonal 0
1 ABIN2742744 IHC IHC (p) WB Rabbit Internal Region Log in to see Polyclonal 0
1 ABIN6104334 ELISA IHC WB Rabbit IgG pThr184 Log in to see Polyclonal 0
1 ABIN6105080 ELISA IHC WB Rabbit IgG pSer439 Log in to see Polyclonal 0
1 ABIN6104570 ELISA IHC WB Rabbit IgG Ser439 Log in to see Polyclonal 0
1 ABIN6104766 ELISA IHC WB Rabbit IgG Thr187 Log in to see Polyclonal 0

General

Antigen Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) Antibodies
Epitope pThr187
(34), (20), (14), (13), (11), (10), (10), (10), (8), (7), (6), (5), (4), (4), (4), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(199), (81), (66), (5), (5), (4), (4), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1)
Host Rabbit
(172), (15), (14)
Clonality
Polyclonal
Conjugate This MAP3K7 antibody is un-conjugated
(10), (10), (10), (9), (9), (9)
Application ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
(161), (126), (72), (39), (20), (7), (5), (5), (3), (1), (1), (1)
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Product Details anti-MAP3K7 Antibody

Target Details MAP3K7 Application Details Handling Images
Specificity Phospho-MAP3K7 (Thr187) Antibody detects endogenous levels of MAP3K7 only when phosphorylated at Threonine 187
Cross-Reactivity Human, Mouse (Murine), Rat (Rattus)
Purification The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Immunogen A synthesized peptide derived from human MAP3K7 around the phosphorylation site of Threonine 187
Isotype IgG
Plasmids, Primers & others

Target Details MAP3K7

Product Details anti-MAP3K7 Antibody Application Details Handling Images back to top
Antigen
Alternative Name MAP3K7 (MAP3K7 Antibody Abstract)
Background

Description: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signal transduction of TRAF6, various cytokines including interleukin-1 (IL-1), transforming growth factor-beta (TGFB), TGFB-related factors like BMP2 and BMP4, toll-like receptors (TLR), tumor necrosis factor receptor CD40 and B-cell receptor (BCR). Ceramides are also able to activate MAP3K7/TAK1. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade and the p38 MAPK signal transduction cascade through the phosphorylation and activation of several MAP kinase kinases like MAP2K1/MEK1, MAP2K3/MKK3, MAP2K6/MKK6 and MAP2K7/MKK7. These MAP2Ks in turn activate p38 MAPKs, c-jun N-terminal kinases (JNKs) and I-kappa-B kinase complex (IKK). Both p38 MAPK and JNK pathways control the transcription factors activator protein-1 (AP-1), while nuclear factor-kappa B is activated by IKK. MAP3K7 activates also IKBKB and MAPK8/JNK1 in response to TRAF6 signaling and mediates BMP2-induced apoptosis. In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK1, but not that of NF-kappa-B. Promotes TRIM5 capsid-specific restriction activity.

Gene: MAP3K7

Molecular Weight 70kDa
Gene ID 6885
UniProt O43318
Pathways NF-kappaB Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Toll-Like Receptors Cascades

Application Details

Product Details anti-MAP3K7 Antibody Target Details MAP3K7 Handling Images back to top
Application Notes WB 1:500-1:2000 IHC 1:50-1:500, IF/ICC 1:100-1:500
Restrictions For Research Use only

Handling

Product Details anti-MAP3K7 Antibody Target Details MAP3K7 Application Details Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20 °C.Stable for 12 months from date of receipt
Expiry Date 12 months

Images

Product Details anti-MAP3K7 Antibody Target Details MAP3K7 Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (pThr187) antibody (ABIN6256492) Western blot analysis of MAP3K7 phosphorylation expression in NIH-3T3 whole cell lysa...
Immunofluorescence (fixed cells) (IF/ICC) image for anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (pThr187) antibody (ABIN6256492) ABIN6267236 staining HepG2 by IF/ICC. The sample were fixed with PFA and permeabilize...
Immunohistochemistry (IHC) image for anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (pThr187) antibody (ABIN6256492) ABIN6267236 at 1/100 staining mouse spleen tissue sections by IHC-P. The tissue was f...
Immunohistochemistry (IHC) image for anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (pThr187) antibody (ABIN6256492) ABIN6267236 at 1/100 staining mouse brain tissue sections by IHC-P. The tissue was fo...
Immunohistochemistry (IHC) image for anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (pThr187) antibody (ABIN6256492) ABIN6267236 at 1/100 staining mouse testis tissue sections by IHC-P. The tissue was f...
Immunohistochemistry (IHC) image for anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (pThr187) antibody (ABIN6256492) ABIN6267236 at 1/100 staining human pancreas tissue sections by IHC-P. The tissue was...
Immunohistochemistry (IHC) image for anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (pThr187) antibody (ABIN6256492) ABIN6267236 at 1/100 staining human appendiceal tissue sections by IHC-P. The tissue ...
Immunohistochemistry (IHC) image for anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (pThr187) antibody (ABIN6256492) ABIN6267236 at 1/100 staining rat uterine tissue sections by IHC-P. The tissue was fo...
Immunohistochemistry (IHC) image for anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (pThr187) antibody (ABIN6256492) ABIN6267236 at 1/100 staining rat spleen tissue sections by IHC-P. The tissue was for...
Immunohistochemistry (IHC) image for anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (pThr187) antibody (ABIN6256492) ABIN6267236 at 1/100 staining rat ovarian tissue sections by IHC-P. The tissue was fo...