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|Antigen||Nerve Growth Factor beta (NGFB) Antibodies|
|Epitope||Middle Region Alternatives|
|Conjugate||This NGFB antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
|3 references available|
|Supplier||Log in to see|
Product Details anti-NGFB AntibodyTarget Details NGFB Application Details Handling References for anti-NGFB antibody (ABIN360076) Images
|Specificity||This antibody reacts to NGFB.|
|Purification||Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS|
|Immunogen||This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human NGFB.|
Target Details NGFBProduct Details anti-NGFB Antibody Application Details Handling References for anti-NGFB antibody (ABIN360076) Images back to top
|Alternative Name||NGF (NGFB Antibody Abstract)|
|Background||NGFB is a member of the NGF-beta family. It is a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in the gene encoding NGFB have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of the gene's expression is associated with allergic rhinitis.Synonyms: Beta-NGF, Beta-nerve growth factor, NGFB|
|Gene ID||4803, 9606|
|Research Area||Neurology, Growth Factors|
|Pathways||NF-kappaB Signaling, RTK Signaling, Regulation of Cell Size|
Application DetailsProduct Details anti-NGFB Antibody Target Details NGFB Handling References for anti-NGFB antibody (ABIN360076) Images back to top
ELISA: 1/1,000. Immunohistochemistry: 1/10 - 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
|Restrictions||For Research Use only|
HandlingProduct Details anti-NGFB Antibody Target Details NGFB Application Details References for anti-NGFB antibody (ABIN360076) Images back to top
|Buffer||PBS with 0.09 % (W/V) sodium azide|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.|
References for anti-NGFB antibody (ABIN360076)Product Details anti-NGFB Antibody Target Details NGFB Application Details Handling Images back to top
Lang, Hellweg, Bajbouj, Gaus, Sander, Gallinat: "Gender-dependent association of a functional NGF polymorphism with anxiety-related personality traits." in: Pharmacopsychiatry, Vol. 41, Issue 5, pp. 196-9, 2008
Truzzi, Marconi, Lotti, Dallaglio, French, Hempstead, Pincelli: "Neurotrophins and their receptors stimulate melanoma cell proliferation and migration." in: The Journal of investigative dermatology, Vol. 128, Issue 8, pp. 2031-40, 2008
MacGrogan, Saint-André, Dicou: "Expression of nerve growth factor and nerve growth factor receptor genes in human tissues and in prostatic adenocarcinoma cell lines." in: Journal of neurochemistry, Vol. 59, Issue 4, pp. 1381-91, 1992
ImagesProduct Details anti-NGFB Antibody Target Details NGFB Application Details Handling References for anti-NGFB antibody (ABIN360076) back to top