anti-Mouse (Murine) Estrogen-Related Receptor alpha antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended Estrogen-Related Receptor alpha Antibody (supplied by: Log in to see )

Antigen
Estrogen-Related Receptor alpha (ESRRA) Antibodies
  • err1
  • erra
  • esrral
  • erralpha
  • nr3b1
  • MGC80854
  • ESRRA
  • esrl1
  • LOC100125507
  • ERRalpha
  • Err1
  • Estrra
  • Nr3b1
  • Errra
  • ERR1
  • ERRa
  • ESRL1
  • NR3B1
  • ESTRRA
  • estrogen-related receptor alpha
  • estrogen related receptor alpha L homeolog
  • estrogen related receptor alpha
  • catsper channel auxiliary subunit zeta
  • estrogen related receptor, alpha
  • esrra
  • esrra.L
  • ESRRA
  • LOC100125507
  • CATSPERZ
  • Esrra
Epitope
AA 1-50, N-Term
11
10
10
9
8
7
5
4
3
3
2
2
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
93
30
27
11
8
5
5
3
2
2
2
1
Host
Rabbit
75
21
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
1
1
1
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
81
29
24
13
13
11
10
9
5
2
1
1
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Catalog No. ABIN4309527
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
10.613991 ABIN4309525 ChIP IHC (p) Rabbit Log in to see Polyclonal 3
7 ABIN1048580 ChIP IHC IHC (p) Rabbit Internal Region Log in to see Polyclonal 0
7 ABIN1048581 IHC IHC (p) Rabbit Ligand Binding Domain Log in to see Polyclonal 0
3.1139913 ABIN271168 IHC (p) Rabbit Log in to see Polyclonal 0
1 ABIN5556817 IHC (p) Rabbit Log in to see Polyclonal 0
1 ABIN5556818 IHC (p) Rabbit Log in to see Polyclonal 0
-10.419104 ABIN4309526 ICC IF IHC IHC (p) WB Rabbit AA 1-50, N-Term Log in to see Polyclonal 0
-10.419104 ABIN4270558 ICC IF IHC IHC (p) FITC Rabbit AA 1-50, N-Term Log in to see Polyclonal 0
-10.419104 ABIN4309528 ICC IF IHC IHC (p) WB Biotin Rabbit AA 1-50, N-Term Log in to see Polyclonal 0
-10.419104 ABIN4309529 ICC IF IHC IHC (p) WB DyLight 650 Rabbit AA 1-50, N-Term Log in to see Polyclonal 0
-10.419104 ABIN4309531 ICC IF IHC IHC (p) WB DyLight 550 Rabbit AA 1-50, N-Term Log in to see Polyclonal 0
-10.419104 ABIN4309533 ICC IF IHC IHC (p) WB DyLight 405 Rabbit AA 1-50, N-Term Log in to see Polyclonal 0
-10.419104 ABIN4309536 ICC IF IHC IHC (p) WB Alexa Fluor 488 Rabbit AA 1-50, N-Term Log in to see Polyclonal 0
-10.419104 ABIN4309538 ICC IF IHC IHC (p) WB Alexa Fluor 700 Rabbit AA 1-50, N-Term Log in to see Polyclonal 0
-10.419104 ABIN4309530 ICC IF IHC IHC (p) WB DyLight 488 Rabbit AA 1-50, N-Term Log in to see Polyclonal 0
-10.419104 ABIN4270555 IHC IHC (p) WB HRP Rabbit AA 1-50, N-Term Log in to see Polyclonal 0

General

Antigen Estrogen-Related Receptor alpha (ESRRA) Antibodies
Epitope AA 1-50, N-Term
(11), (10), (10), (9), (8), (7), (5), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(93), (30), (27), (11), (8), (5), (5), (3), (2), (2), (2), (1)
Host Rabbit
(75), (21)
Clonality
Polyclonal
Conjugate Un-conjugated
(2), (2), (2), (2), (2), (2), (1), (1), (1)
Application Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(81), (29), (24), (13), (13), (11), (10), (9), (5), (2), (1), (1)
Pubmed 5 references available
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Product details

Target Details Application Details Handling References Images
Purification Immunogen affinity purified
Immunogen Synthetic peptide made to an N-terminal portion of human Estrogen Related Receptor alpha (within residues 1-50). [Swiss-Prot# P11474]

Target Details

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Antigen
Alternative Name ERR alpha/nr3b1 (ESRRA Antibody Abstract)
Background Gene Symbol: ESRRA
Molecular Weight Theoretical MW: 50 kDa
Gene ID 2101
UniProt P11474
Pathways Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha

Application Details

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Application Notes Western Blot 2 μg/mL, Immunohistochemistry 2 μg/mL, Immunocytochemistry/Immunofluorescence 1:100, Immunohistochemistry-Paraffin 2 μg/mLThis Estrogen Related Receptor alpha antibody is useful for Western Blot, Immunohistochemistry-Paraffin and Immunocytochemistry/Immunofluorescence applications. ERR alpha/ ESRRA localize mainly to the nucleus, but there are reports on its cytoplasmic presence also, especially in cells with high nuclear expression. In a feedback loop mechanism, it has been shown that ERK8/MAPK15 interacts with ERR alpha to induce its CRM1-dependent translocation to cytoplasm for inhibiting its transcriptional activity via regulation of its cellular localization (PMIDs 21190936, 18070081). The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only

Handling

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Format Liquid
Concentration 1 mg/mL
Buffer PBS and 30 % Glycerol
Buffer contains: 0.1 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

References

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Product cited in:

Hauck, Stanley-Hasnain, Fung, Grothe, Rao, Mak, Billia: "Cardiac-specific ablation of the E3 ubiquitin ligase Mdm2 leads to oxidative stress, broad mitochondrial deficiency and early death." in: PLoS ONE, Vol. 12, Issue 12, pp. e0189861, 2018 Method employed by authors: Western Blotting (WB) (Sample species: Mouse (Murine)).

Mak, Hauck, Grothe, Billia: "p53 regulates the cardiac transcriptome." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 114, Issue 9, pp. 2331-2336, 2017

Hwang, Purdy, Wu, Rabinowitz, Shenk: "Estrogen-related receptor α is required for efficient human cytomegalovirus replication." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 52, pp. E5706-15, 2014 (Sample species: Human). Further details: Western Blotting

Silvennoinen, Rinnankoski-Tuikka, Vuento, Hulmi, Torvinen, Lehti, Kivelä, Kainulainen: "High-fat feeding induces angiogenesis in skeletal muscle and activates angiogenic pathways in capillaries." in: Angiogenesis, Vol. 16, Issue 2, pp. 297-307, 2013 (Sample species: Human). Further details: Western Blotting

Rinnankoski-Tuikka, Silvennoinen, Torvinen, Hulmi, Lehti, Kivelä, Reunanen, Kainulainen: "Effects of high-fat diet and physical activity on pyruvate dehydrogenase kinase-4 in mouse skeletal muscle." in: Nutrition & metabolism, Vol. 9, Issue 1, pp. 53, 2012 (Sample species: Mouse (Murine)). Further details: Western Blotting

Images

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Supplier Images
Western Blotting (WB) image for anti-Estrogen-Related Receptor alpha (ESRRA) (AA 1-50), (N-Term) antibody (ABIN4309527) Western Blot: ERR alpha/NR3B1 Antibody [NBP1-47254] - Analysis of ERR alpha in A431 c...
Immunofluorescence (IF) image for anti-Estrogen-Related Receptor alpha (ESRRA) (AA 1-50), (N-Term) antibody (ABIN4309527) Immunocytochemistry/Immunofluorescence: ERR alpha/NR3B1 Antibody [NBP1-47254] - ERR a...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Estrogen-Related Receptor alpha (ESRRA) (AA 1-50), (N-Term) antibody (ABIN4309527) Immunohistochemistry-Paraffin: ERR alpha/NR3B1 Antibody [NBP1-47254] - IHC-P detectio...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Estrogen-Related Receptor alpha (ESRRA) (AA 1-50), (N-Term) antibody (ABIN4309527) Immunohistochemistry-Paraffin: ERR alpha/NR3B1 Antibody [NBP1-47254] - IHC-P detectio...