anti-Human Progesterone Receptor antibody for Enzyme Immunoassay

Recommended Progesterone Receptor Antibody (supplied by: Log in to see )

Antigen
Progesterone Receptor (PGR) Antibodies
  • NR3C3
  • PR
  • 9930019P03Rik
  • BB114106
  • ENSMUSG00000074510
  • PR-A
  • PR-B
  • XPR-1
  • pgr
  • xpr-2
  • LOC443444
  • PGR
  • pg
  • pr
  • gb:dq017620
  • progesterone receptor
  • progesterone receptor L homeolog
  • PGR
  • Pgr
  • pgr.L
  • pgr
Epitope
AA 348-377, Middle Region
53
52
40
33
26
19
19
18
18
17
16
15
10
10
9
8
8
8
7
7
7
5
5
4
4
4
3
3
3
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
524
93
89
20
11
11
9
6
6
5
4
4
2
1
1
1
1
1
1
1
Host
Rabbit
315
219
3
1
Clonality
Polyclonal
Conjugate
This Progesterone Receptor antibody is un-conjugated
17
17
14
9
9
9
2
2
2
2
2
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
411
175
145
142
95
48
41
27
21
9
8
5
3
2
2
1
1
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Catalog No. ABIN954305
$ 390.50
Plus shipping costs $45.00

General

Antigen Progesterone Receptor (PGR) Antibodies
Epitope AA 348-377, Middle Region
(53), (52), (40), (33), (26), (19), (19), (18), (18), (17), (16), (15), (10), (10), (9), (8), (8), (8), (7), (7), (7), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(524), (93), (89), (20), (11), (11), (9), (6), (6), (5), (4), (4), (2), (1), (1), (1), (1), (1), (1), (1)
Host Rabbit
(315), (219), (3), (1)
Clonality
Polyclonal
Conjugate This Progesterone Receptor antibody is un-conjugated
(17), (17), (14), (9), (9), (9), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(411), (175), (145), (142), (95), (48), (41), (27), (21), (9), (8), (5), (3), (2), (2), (1), (1)
Pubmed 2 references available
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Product Details anti-Progesterone Receptor Antibody

Target Details Progesterone Receptor Application Details Handling References for anti-Progesterone Receptor antibody (ABIN954305) Images
Specificity This antibody recognizes Human Progesterone receptor (Center).
Purification Protein A column, followed by peptide affinity purification
Immunogen KLH conjugated synthetic peptide between 348-377 amino acids from the Central region of human Progesterone receptor Genename: PGR
Isotype Ig Fraction

Target Details Progesterone Receptor

Product Details anti-Progesterone Receptor Antibody Application Details Handling References for anti-Progesterone Receptor antibody (ABIN954305) Images back to top
Antigen
Alternative Name Progesterone Receptor (PGR Antibody Abstract)
Background This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform A has not been clearly determined.Synonyms: NR3C3, Nuclear Receptor Subfamily 3 Group C Member 3, PGR, PR
Molecular Weight 98981 Da
Gene ID 5241
NCBI Accession NP_000917
Pathways Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration

Application Details

Product Details anti-Progesterone Receptor Antibody Target Details Progesterone Receptor Handling References for anti-Progesterone Receptor antibody (ABIN954305) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-Progesterone Receptor Antibody Target Details Progesterone Receptor Application Details References for anti-Progesterone Receptor antibody (ABIN954305) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-Progesterone Receptor antibody (ABIN954305)

Product Details anti-Progesterone Receptor Antibody Target Details Progesterone Receptor Application Details Handling Images back to top
Background publications

Tang, Wang, Hicks, Wang, Schiffhauer, McMahon, Yang, Shayne, Huston, Skinner, Griggs, Lyman: "A lower Allred score for progesterone receptor is strongly associated with a higher recurrence score of 21-gene assay in breast cancer." in: Cancer investigation, Vol. 28, Issue 9, pp. 978-82, 2010

Geradts, Bean, Bentley, Barry: "The oncotype DX recurrence score is correlated with a composite index including routinely reported pathobiologic features." in: Cancer investigation, Vol. 28, Issue 9, pp. 969-77, 2010

Images

Product Details anti-Progesterone Receptor Antibody Target Details Progesterone Receptor Application Details Handling References for anti-Progesterone Receptor antibody (ABIN954305) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Progesterone Receptor (PGR) (AA 348-377), (Middle Region) antibody (ABIN954305) Immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus ti...
Western Blotting (WB) image for anti-Progesterone Receptor (PGR) (AA 348-377), (Middle Region) antibody (ABIN954305) Western blot analysis of PGR Antibody (Center) in T47D cell line lysates (35ug/lane)....