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|Antigen||Carboxypeptidase E (CPE) Antibodies|
Immunoprecipitation (IP), ELISA, Western Blotting (WB)
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|Immunogen||Carboxypeptidase E antibody was raised in mouse using purified, NSO-derived, recombinant human CPE as the immunogen.|
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|Alternative Name||Carboxypeptidase E (CPE Antibody Abstract)|
|Background||Carboxypeptidase E (CPE) is a peripheral membrane protein that cleaves C-terminal amino acid residues and is involved in the processing of numerous peptide hormones and neurotransmitters. CPE knockout mice live but become obese due to impaired glucose clearance and insulin resistance. The CPE precursor includes a signal peptide (aa 1 - 25), a propeptide (aa 26 - 42) and a mature chain (aa 43 - 476). The amino acid sequence of human CPE is 99.8%, 96.6%, 96.3%, and 90.2% identical to that of chimpanzee, mouse, dog and chicken. Synonyms: Monoclonal Carboxypeptidase E antibody, Anti-Carboxypeptidase E antibody.|
|Pathways||Peptide Hormone Metabolism, Synaptic Membrane|
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ELISA: 0.5-1.0 µg/mL, IP: 25 µg/mL, WB: 1-2 µg/mL
Optimal conditions should be determined by the investigator.
|Restrictions||For Research Use only|
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|Reconstitution||Reconstitute with sterile PBS. If 0.2 mL of PBS is used, the antibody concentration will be 0.5 mg/mL.|
|Buffer||Supplied lyophilized from a 0.2 µm filtered solution in PBS, with 5 % Trehalose.|
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.
|Storage Comment||Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.|