anti-Human GATA4 antibody for Western Blotting

Recommended GATA4 Antibody (supplied by: Log in to see )

Antigen
GATA Binding Protein 4 (GATA4) Antibodies
  • gata-4
  • xgata4
  • xGATA-4
  • MGC81427
  • GATA4
  • GATA-4
  • Gata4
  • gata4
  • ASD2
  • VSD1
  • Gata-4
  • gata
  • GATA binding protein 4
  • GATA binding protein 4 L homeolog
  • glutamyl-tRNA(Gln) amidotransferase subunit A
  • gata4 transcription factor
  • GATA binding protein 4 S homeolog
  • GATA4
  • gata4.L
  • gata4
  • gatA4
  • Gata4
  • gata4.S
Reactivity
Human, Rat (Rattus)
178
121
100
11
8
3
3
3
2
2
1
1
1
Host
Mouse
136
33
16
1
Clonality
Monoclonal
Conjugate
This GATA4 antibody is un-conjugated
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
161
72
46
40
22
18
13
9
7
5
2
2
1
Options
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Catalog No. ABIN969169
$ 442.20
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
19.802612 ABIN6256227 ELISA ICC IF IHC WB Rabbit IgG pSer262 Log in to see Polyclonal 0
19.802612 ABIN6256094 ELISA ICC IF IHC WB Rabbit IgG pSer105 Log in to see Polyclonal 0
19.558292 ABIN3184753 ELISA IHC WB Rabbit IgG Internal Region Log in to see Polyclonal 0
19 ABIN1491352 IF IHC IHC (p) WB Mouse IgG3 AA 296-442 Log in to see 9F9 0
16.558292 ABIN3184752 ELISA IF WB Rabbit IgG Ser422 Log in to see Polyclonal 0
16.558292 ABIN3184751 ELISA IF IHC WB Rabbit IgG Ser422 Log in to see Polyclonal 0
16.558292 ABIN5596711 ELISA WB Mouse IgG1 N-Term Log in to see 10D8-B10-D4 0
16.558292 ABIN933061 ELISA WB Mouse IgG2b Log in to see 6H10 0
16.558292 ABIN5664351 WB Rabbit Log in to see Polyclonal 0
12.755681 ABIN3182442 ELISA IF WB Rabbit IgG pSer262 Log in to see Polyclonal 0
12.755681 ABIN4901592 ELISA WB Mouse IgG2b Log in to see 6H10 0
12.755681 ABIN5619730 ICC IF IHC WB Rabbit Center Log in to see Polyclonal 0
12.755681 ABIN5619729 IHC WB Rabbit Center Log in to see Polyclonal 0
12.755681 ABIN871142 WB Rabbit IgG Log in to see Polyclonal 0
12.755681 ABIN2140187 WB Mouse IgG2b AA 296-442 Log in to see 1H8 0
12.755681 ABIN2140188 IF IHC WB Mouse IgG3 AA 296-442 Log in to see 9F9 0
12.755681 ABIN2141216 IF ELISA WB Rabbit IgG Ser262 Log in to see Polyclonal 0
12.755681 ABIN2140784 IF ELISA WB Rabbit IgG pSer262 Log in to see Polyclonal 0
12.755681 ABIN2141176 IF ELISA WB Rabbit IgG Ser105 Log in to see Polyclonal 0
12.755681 ABIN2142371 ELISA WB Rabbit IgG Log in to see Polyclonal 0

General

Antigen GATA Binding Protein 4 (GATA4) Antibodies
Reactivity Human, Rat (Rattus)
(178), (121), (100), (11), (8), (3), (3), (3), (2), (2), (1), (1), (1)
Host Mouse
(136), (33), (16), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This GATA4 antibody is un-conjugated
(3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application ELISA, Western Blotting (WB)
(161), (72), (46), (40), (22), (18), (13), (9), (7), (5), (2), (2), (1)
Pubmed 3 references available
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Product Details anti-GATA4 Antibody

Target Details GATA4 Application Details Handling References for anti-GATA4 antibody (ABIN969169) Images
Purification Ascites
Immunogen Purified recombinant fragment of human GATA4 expressed in E. Coli.
Clone 6H10
Isotype IgG2b
Plasmids, Primers & others

Target Details GATA4

Product Details anti-GATA4 Antibody Application Details Handling References for anti-GATA4 antibody (ABIN969169) Images back to top
Antigen
Alternative Name GATA4 (GATA4 Antibody Abstract)
Background GATA binding protein 4, also known as GATA4, it is a 46 kDa member of the GATA family of zinc-finger transcription factors. Members of this family is involved in the development of cardiac hypertrophy and remodeling, and plays a critical role in regulating basal and agonist or stress induced gene expression in cardiac and smooth muscle cell types. These factors recognize the GATA motif which is present in the promoters of many genes. GATA4 contains a conserved MAPK phosphorylation site at serine 105 within the transcriptional activation domain. Serine 105 of GATA4 is phosphorylated in response to agonist stimulation through MEK 1 ERK1 / 2, and weakly through JNK or p38 MAPKs. GATA4 is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function. Mutations in this gene have been associated with cardiac septal defects.
Molecular Weight 46 kDa
Gene ID 2626
HGNC 2626
Pathways Peptide Hormone Metabolism, Carbohydrate Homeostasis

Application Details

Product Details anti-GATA4 Antibody Target Details GATA4 Handling References for anti-GATA4 antibody (ABIN969169) Images back to top
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000
Restrictions For Research Use only

Handling

Product Details anti-GATA4 Antibody Target Details GATA4 Application Details References for anti-GATA4 antibody (ABIN969169) Images back to top
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage

References for anti-GATA4 antibody (ABIN969169)

Product Details anti-GATA4 Antibody Target Details GATA4 Application Details Handling Images back to top
Product cited in:

Rajagopal, Ma, Obler, Shen, Manichaikul, Tomita-Mitchell, Boardman, Briggs, Garg, Srivastava, Goldmuntz, Broman, Benson, Smoot, Pu: "Spectrum of heart disease associated with murine and human GATA4 mutation." in: Journal of molecular and cellular cardiology, Vol. 43, Issue 6, pp. 677-85, 2007

Belaguli, Sepulveda, Nigam, Charron, Nemer, Schwartz: "Cardiac tissue enriched factors serum response factor and GATA-4 are mutual coregulators." in: Molecular and cellular biology, Vol. 20, Issue 20, pp. 7550-8, 2000

Background publications

Durocher, Charron, Warren, Schwartz, Nemer: "The cardiac transcription factors Nkx2-5 and GATA-4 are mutual cofactors." in: The EMBO journal, Vol. 16, Issue 18, pp. 5687-96, 1997

Images

Product Details anti-GATA4 Antibody Target Details GATA4 Application Details Handling References for anti-GATA4 antibody (ABIN969169) back to top
Supplier Images
Western Blotting (WB) image for anti-GATA Binding Protein 4 (GATA4) antibody (ABIN969169) Figure 1: Western blot analysis using GATA4 mouse mAb against rat fetal heart (1) and...